Acetal Soluble is indicated for the treatment of acute and chronic diseases of the bronchopulmonary system, accompanied by increased production of sputum.
Active ingredient: acetylcysteine.
1 tablet contains acetylcysteine 200 mg.
Excipients: sodium bicarbonate, citric acid, aspartame (E951), lemon flavoring containing maltodextrin; gum arabic (E414) citric acid.
Hypersensitivity to acetylcysteine or to any of the excipients. Peptic ulcer and duodenal ulcer in the acute stage, hemoptysis, pulmonary hemorrhage.
Children aged 2 to 5 years take ½ tablets of 200 mg (100 mg of acetylcysteine) 2-3 times a day (200-300 mg of acetylcysteine per day).
Children aged 6 to 14 years, take 1 tablet 200 mg 2 times a day (400 mg of acetylcysteine per day).
Adults and children over 14 years of age take 1 tablet of 200 mg 2-3 times a day (400 mg - 600 mg of acetylcysteine per day).
Effervescent tablets dissolve in a glass of water and apply after meals.
The doctor determines the duration of the course of treatment individually, depending on the nature of the disease (acute or chronic).
Pregnant
Clinical data on the use of acetylcysteine in pregnant women are limited. Animal studies have shown no direct or indirect adverse effects on pregnancy, embryofetal development, childbirth and postnatal development.
Children
For use in children over 2 years of age.
Drivers
There is no confirmation that acetylcysteine affects the ability to drive a car and other mechanisms.
There are no data on cases of overdose of oral dosage forms of acetylcysteine.
It is known that the volunteers took 11.6 g of acetylcysteine for 3 months without any serious side effects.
Acetylcysteine, when used in doses of 500 mg / kg / day, does not cause an overdose.
Symptoms Overdose can present with gastrointestinal symptoms such as nausea, vomiting, and diarrhea.
Treatment. There is no specific antidote for acetylcysteine poisoning, therapy is symptomatic.
In very rare cases, skin reactions such as Stevens-Johnson syndrome and Lyell's syndrome have been reported in connection with the use of acetylcysteine. In most cases, at least one other drug may be more likely to cause mucocutaneous syndrome. Therefore, if any new changes appear on the skin or mucous membranes, you should consult a doctor and immediately stop taking acetylcysteine.
The use of antitussives with acetylcysteine can increase sputum congestion due to suppression of the cough reflex.
Activated carbon reduces the effectiveness of acetylcysteine.
With simultaneous use with antibiotics such as tetracycline (with the exception of doxycycline), ampicillin, amphotericin B, cephalosporins, aminoglycosides, their interaction with the thiol group of acetylcysteine is possible, which leads to a decrease in the activity of both drugs. Therefore, the interval between the use of these drugs should be at least 2 hours. This does not apply to cefixime and loracarbef.
With the simultaneous administration of nitroglycerin and acetylcysteine, significant hypotension and expansion of the temporal artery were found. If necessary, the simultaneous use of nitroglycerin and acetylcysteine in patients should be monitored for hypotension, which can be severe, and should be warned of the possibility of headache.
Acetylcysteine can donate cysteine and increase glutathione levels, which helps detoxify free oxygen radicals and certain toxic substances in the body.
Store in its original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
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