Pharmacodynamics. The properties of the preparation are due to the action of its three active ingredients - hexetidine, choline salicylate, chlorobutanol hemihydrate.
The antibacterial and antifungal effect is due to hexetidine, which exhibits antibacterial activity against gram-positive and gram-negative microorganisms (both aerobes and anaerobes). In relation to aerobic microorganisms, it has mainly a bacteriostatic effect and a weak bactericidal effect. Heksetidine has a pronounced bactericidal effect on anaerobic microorganisms. The mechanism of action of hexetidine is based on the competitive substitution of thiamine: the structure of hexetidine is similar to that of thiamine, which is necessary for the growth of microorganisms.
The anti-inflammatory effect is due to choline salicylate, which belongs to the group of NSAIDs and has analgesic, antipyretic and anti-inflammatory effects.
The analgesic activity is also due to the local anesthetic chlorobutanol, which is used in otolaryngology (nasal drops, rinsing) and dentistry (applications and irrigation), mainly as a pain reliever.
Pharmacokinetics. The active substances are fixed on the mucous membrane of the oral cavity, from where they are then gradually released.
Local treatment of diseases and inflammatory processes of the oral cavity and pharynx in adults and children over 2.5 years of age: gingivitis, stomatitis; periodontitis; aphthae and teething pain; postoperative oral care; angina, acute and chronic tonsillitis, pharyngitis, laryngitis.
R – r is used as a local mouth rinse.
For one mouthwash: Dissolve 2 teaspoons of the preparation in ¼ glass of warm water. 2 to 4 rinses per day. Do not swallow.
The spray is used to irrigate the oral cavity.
Adults: 1 spray 4-6 times a day
Children aged 2.5 to 15 years: 1 spray 2-3 times a day.
The course of treatment is no more than 5 days.
Do not use in children under the age of 2.5 years. do not use in case of detection of allergy to the components of the preparation.
Allergic reactions: irritation, skin reactions. in this case, treatment must be discontinued.
Long-term use is not recommended, as this can lead to an imbalance in the microbial balance in the mouth and throat.
Application during pregnancy or lactation. During pregnancy and lactation, the preparation is used only as directed by a doctor and only if the benefits of using the preparation for the mother outweigh the risk to the fetus.
The ability to influence the reaction rate when driving or working with other mechanisms. Does not affect.
Children. Used in children over the age of 2.5 years. The safety of using the preparation in children under 2.5 years of age has not been studied.
Do not use simultaneously with preparations containing antiseptics.
There have been no reports of preparation overdose.
At a temperature not higher than 25 ° C. do not freeze.
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