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    3. Barboval oral drops 2p x 25 ml — Made in Ukraine — Free Delivery

    Barboval oral drops 2p x 25 ml — Made in Ukraine — Free Delivery


    Brand: Farmak
    Product Code: Barboval
    Availability: In Stock
    $19.79
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    Indication

    Neuroses accompanied by increased excitability, insomnia, hysteria; as part of the complex treatment of mild attacks of angina pectoris, angina pectoris of the initial stage, tachycardia of functional genesis, with spasms of the stomach and intestines, flatulence.

    Application

    Barboval should be taken internally with a small amount of liquid or on a piece of sugar under the tongue.
    Doses and duration of treatment are set by the doctor individually. Adults usually take 10-15 drops 2-3 times a day for 10-15 days.
    It is better to take the preparation 20-30 minutes before meals.
    After a break of 10-15 days, the course of treatment can be repeated.

    Contraindication

    Hypersensitivity to any components of the preparation, liver and kidney failure, hepatic porphyria, severe heart failure, severe arterial hypotension, acute myocardial infarction, diabetes, depression, myasthenia gravis, alcoholism, preparation and medication addiction, respiratory diseases with shortness of breath, obstructive syndrome .

    Side effects

    Usually the preparation is well tolerated. the development of the following adverse reactions is possible:
    • from the side of the digestive system: constipation, a feeling of heaviness in the epigastric region, with long-term use - impaired liver function, nausea, vomiting;
    • from the nervous system: weakness, ataxia, impaired coordination of movements, nystagmus, hallucinations, paradoxical excitement, decreased concentration of attention, fatigue, slowing of reactions, headache, cognitive impairment, confusion, drowsiness, light dizziness;
    • from the hematopoietic organs: anemia, thrombocytopenia, agranulocytosis;
    • from the side of the cardiovascular system: arterial hypotension, bradycardia; from the immune system: hypersensitivity reactions, including angioedema, allergic reactions, including skin rashes, itching, urticaria;
    • from the skin and mucous membranes: Stevens-Johnson syndrome, toxic epidermal necrolysis;
    • on the part of the musculoskeletal system: with long-term use of preparations containing phenobarbital, there is a risk of osteogenesis disorder;
    • other: difficulty breathing.
    Long-term use of bromine-containing preparations can lead to bromine poisoning, which is characterized by the following symptoms: CNS depression, depressed mood, confusion, ataxia, apathy, conjunctivitis, rhinitis, lacrimation, acne or purpura.

    Special instructions

    The presence of phenobarbital in the medicinal product can lead to the risk of developing Stevens-Johnson and Lyell syndrome, which is most likely in the first weeks of treatment. long-term use is not recommended due to the risk of preparation addiction, possible accumulation of bromine in the body and the development of bromine poisoning. in cases where the pain in the heart area does not go away after taking the preparation, it is necessary to consult a doctor to rule out acute coronary syndrome. the preparation should be prescribed with caution in arterial hypotension, hyperkinesis, hyperthyroidism, hypofunction of the adrenal glands, acute and constant pain, acute preparation intoxication.
    Use during pregnancy or breastfeeding. The preparation should not be used by women during pregnancy or breastfeeding.
    The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. The preparation can cause drowsiness and dizziness, therefore, during treatment, patients are not recommended to work with dangerous mechanisms and drive vehicles.
    Children. There is no experience of using the preparation to treat children, so they are used in pediatric practice.

    Interactions

    Simultaneous use with neuroleptics and tranquilizers potentiates, and with stimulants of the central nervous system - weakens the effect of each component of the preparation. barboval, containing derivatives of barbituric acid, enhances the effect of local anesthetics, analgesics and hypnotics. alcohol enhances the effects of the preparation and can increase its toxicity. the effect of the preparation increases against the background of the use of valproic acid preparations. the presence of phenobarbital in the composition of Barboval can induce liver enzymes, and this makes its simultaneous use with preparations that are metabolized in the liver (with coumarin derivatives, griseofulvin, glucocorticoids, oral contraceptives, cardiac glycosides, antimicrobial, antiviral, antifungal, antiepileptic, anticonvulsant , psychotropic, oral hypoglycemic, hormonal, immunosuppressive, cytostatic, antiarrhythmic, antihypertensive preparations, etc.), as their effectiveness will decrease as a result of a higher level of metabolism. MAO inhibitors prolong the effect of phenobarbital. rifampicin can reduce the effect of phenobarbital.
    With the simultaneous use of phenobarbital with gold preparations, the risk of kidney damage increases.
    With long-term use of phenobarbital with NSAIDs, there is a risk of stomach ulcers and bleeding.
    Simultaneous use of phenobarbital with zidovudine increases the toxicity of both preparations
    The preparation increases the toxicity of methotrexate. Alcohol should be avoided while taking the preparation.

    Overdose

    With long-term or frequent use, preparation accumulation may occur, which leads to clinical manifestations of overdose, namely:
    • depression of the central nervous system, which is eliminated by the use of central nervous system stimulants (caffeine, cordiamine, etc.);
    • nystagmus, ataxia, decrease in blood pressure, deviations in the blood formula.
    Manifestations of chronic bromine poisoning are depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired movement coordination. Symptomatic therapy is prescribed to eliminate these manifestations.
    Continuous long-term use of the preparation can cause addiction, preparation dependence, withdrawal syndrome, and sudden cessation of use - withdrawal syndrome. Long-term use of the preparation is sometimes accompanied by increased psychodynamic activity instead of the expected sedation.
    Symptoms of overdose: suppression of breathing, until it stops; depression of the central nervous system, up to coma; suppression of cardiovascular activity, including rhythm disturbances, lowering of blood pressure, up to a collaptoid state; nausea, weakness, decrease in body temperature, decrease in diuresis.
    Treatment is symptomatic.

    Storage conditions

    In the original packaging at a temperature not higher than 25 °C.

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