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  • Celestoderm-V ointment with garamycin 30 g — Made in Belgium — Free Delivery


    Brand: Schering-Plough Labo N.V.
    Product Code: Celestoderm-V
    Availability: In Stock
    $28.53
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    Indications

    Dermatoses sensitive to corticosteroid therapy and complicated (or suspected of being complicated) by a secondary infection caused by microorganisms susceptible to gentamicin: eczema (atopic, childhood, nummular), contact dermatitis, seborrheic dermatitis, neurodermatitis, solar dermatitis, exfoliative dermatitis, stasis dermatitis , intertriginous dermatitis, psoriasis, anogenital and senile itching.

    Application

    The ointment is applied in a thin layer to the affected areas of the skin 2 times a day, morning and evening. the frequency of application of the preparation is determined individually depending on the severity of the disease. in mild cases, once daily application is usually sufficient; in more severe lesions, more frequent application may be required. the duration of the course of treatment is determined by the severity and course of the disease.

    Contraindications

    Hypersensitivity to active substances or any of the components of the preparation.

    Side effects

    When using topical corticosteroids, the following undesirable effects may occur: burning sensation, skin irritation, itching, dry skin, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis. when using occlusive dressings, skin maceration, secondary infection, skin atrophy, striae, prickly heat occur more often. treatment with gentamicin may be accompanied by transient skin irritation (itching, erythema), which in most cases does not require discontinuation of therapy.

    special instructions

    Celestoderm-V with Garamycin is indicated for external use only and is not intended for use in ophthalmology.
    If irritation or hypersensitivity is noted during the use of the preparation, treatment should be discontinued and another therapy should be selected for the patient. With the local use of antibiotics, the growth of insensitive microflora, including fungal, is occasionally observed. In this case, treatment should be stopped and appropriate therapy prescribed.
    Systemic absorption of gentamicin when applied topically will be higher when treating large areas of the skin, especially with long-term treatment or in violation of the integrity of the skin. In these cases, adverse events associated with systemic absorption of gentamicin may occur. Appropriate precautions should be taken in such cases, especially when treating infants and children.
    Any side effects of systemic corticosteroids, including suppression of the function of the adrenal cortex, can also be observed when using local corticosteroids, especially in children.
    Systemic absorption of local glucocorticosteroids increases with their long-term use, with the treatment of large body surfaces or with the use of occlusive dressings. Appropriate precautions must be taken, especially when treating children.
    Application in pediatrics. Children are more susceptible to the action of local corticosteroids, causing depression of the hypothalamic-pituitary-adrenal system than older patients. This is due to the higher absorption of the preparation in children due to the greater ratio of surface area to body weight. Children receiving local corticosteroids may experience inhibition of the function of the hypothalamic-pituitary-adrenal system, Cushing's syndrome, growth retardation, insufficient weight gain, increased intracranial pressure. Symptoms of adrenal suppression in children include a decrease in plasma cortisol levels and a lack of response to ACTH stimulation. An increase in intracranial pressure is manifested by swelling of the fontanel, headache, bilateral edema of the optic discs.
    During pregnancy and breastfeeding. The safety of topical glucocorticosteroids in pregnant women has not been established. The appointment of this group of preparations during pregnancy is justified only if the potential benefit to the woman outweighs the potential risk to the fetus. During pregnancy, preparations in this group should not be used in large doses or for a long time.
    It is not known whether topical application of corticosteroids through systemic absorption can lead to their penetration into breast milk. The decision to stop breastfeeding or discontinue the preparation  should be made taking into account the need for the use of the preparation for the mother.

    Interactions

    So far not known.

    Overdose

    Excessive or prolonged use of topical glucocorticosteroids can cause depression of the pituitary-adrenal function, which can lead to the development of secondary adrenal insufficiency and the appearance of symptoms of hypercorticism, including Cushing's syndrome. prolonged topical use of gentamicin may lead to the growth of insensitive fungal or bacterial flora.
    Treatment: Appropriate symptomatic treatment is indicated. Acute symptoms of hypercortisolism are usually reversible. If necessary, correction of electrolyte imbalance is indicated. In the case of chronic toxic effects, the gradual abolition of GCS is recommended. With excessive growth of microorganisms, an appropriate antibacterial or antifungal treatment should be selected.

    Storage conditions

    At a temperature not higher than 25°C.

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