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    3. Corvalol - Darnitsa oral drops 2p x 40 ml — Made in Ukraine — Free Delivery

    Corvalol - Darnitsa oral drops 2p x 40 ml — Made in Ukraine — Free Delivery


    Brand: Darnitsa
    Product Code: Corvalol - Darnitsa
    Availability: In Stock
    $34.09
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    Indication

    Neuroses (hypersthenic form); insomnia; vegetative-vascular dystonia and ag (as part of complex treatment); spasm of the coronary arteries of the heart (slightly pronounced), increased heart rate (90 beats / min); as an antispasmodic for intestinal spasm.

    Application

    Per os 15-30 drops with water or on a piece of sugar 2-3 times a day. food intake does not affect the intake of the preparation. a single dose can be increased to 40-50 drops in case of pronounced increase in heart rate and spasm of the coronary arteries of the heart.
    The duration of use is determined by the doctor (determined by the tolerability of the preparation and its clinical effectiveness).

    Contraindication

    Increased sensitivity to the components of the preparation, bromine; pronounced liver and / or kidney function disorders; hepatic forms of porphyria; severe heart failure.
    Medicinal products containing phenobarbital are not used:
    • with preparation and medication addiction; alcoholism;
    • in patients with depression;
    • with pathology of the respiratory system, which is accompanied by shortness of breath, obstructive syndrome;
    • in patients with diabetes;
    • with a decrease in blood pressure (pronounced);
    • in case of acute myocardial infarction;
    • with myasthenia;
    • during pregnancy and breastfeeding;
    • if the patient's age is ≤18 years (there are no data on use in the specified age group).

    Side effects

    • corvalol-Darnytsia is generally well tolerated.
    Side effects, possible in some cases, are as follows:

    • digestive system: constipation, a feeling of heaviness in the epigastric area.
    • Long-term use of the preparation can cause liver dysfunction, episodes of nausea or vomiting;
    • nervous system: dizziness (slightly pronounced), impaired coordination of movements, ataxia, nystagmus, weakness, fatigue, slowing down of the speed of reactions, hallucinations, headache, disorders of cognitive functions, confusion, drowsiness, paradoxical excitement, decreased concentration of attention;
    • immune system: hypersensitivity reactions (including Quincke's edema);
    • skin and mucous membranes: allergic reactions (including skin rash, itching, urticaria), as well as Lyell's and Stevens-Johnson syndromes (especially possible in the first weeks of treatment);
    • blood system: anemia, thrombocytopenia, agranulocytosis;
    • respiratory system: difficult breathing;
    • cardiovascular system: decrease in heart rate, arterial hypotension;
    • musculoskeletal system: the risk of bone tissue formation disorders (noted with long-term use of phenobarbital as part of medicines).
    A long period of reception can lead to the development of symptoms of bromine intoxication.
    If the dose is reduced or the preparation is discontinued, these effects disappear.

    Special instructions

    Drowsiness and dizziness, coordination disorders, a decrease in the speed of psychomotor reactions during the use of the preparation can be caused by its components - phenobarbital and ethanol. therefore, types of activity that require quick response and concentration of attention are not recommended during the period of use of the preparation.
    The preparation can cause preparation dependence during a long period of administration.
    The ethanol content in the preparation is 56 vol.%.
    Do not combine with alcohol.
    It is necessary to show foresight in patients with epilepsy, as well as in patients with liver pathology.

    Interactions

    The effect of the preparation is enhanced when combined with preparations of central action (depressant type). valproate and ethanol also enhance the effect of corvalol-Darnytsia.
    Induction of liver enzymes by phenobarbital can lead to a decrease in T ½ in preparations whose biotransformation occurs in the liver.
    Taking phenobarbital leads to an increase in the effect of painkillers and preparations for local anesthesia.
    An increase in the period of action of phenobarbital occurs against the background of the use of MAO inhibitors.
    Simultaneous use with rifampicin reduces the activity of phenobarbital.
    The preparation enhances the toxic properties of methotrexate. Simultaneous administration with zidovudine leads to increased toxicity of both zidovudine and methotrexate.
    Long-term use in combination with non-steroidal anti-inflammatory preparations leads to the risk of stomach ulcers, including those complicated by bleeding. Combined use with gold preparations increases the risk of kidney damage.

    Overdose

    Accumulation of the components of the preparation in the body is possible as a result of its long-term or frequent intake. with an increase in the period of use, psychomotor excitement, addiction and withdrawal syndrome may develop.
    Manifested by suppression of CNS functions (including to coma), respiratory suppression (including to cessation of breathing), suppression of cardiovascular activity (including cardiac arrhythmias), lowering of blood pressure (including to a mild form of collapse), lowering of body temperature , decreased education and excretion of urine, nausea and weakness.

    Storage conditions

    At a temperature ≤25 °C in the original packaging. do not expose to freezing.

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