Mild to moderate arterial hypertension and angina pectoris.
active ingredient: diltiazem;
1 tablet contains diltiazem hydrochloride 120 mg
excipients: lactose, magnesium stearate, hypromellose, povidone.
The tablet should be swallowed whole with a small amount of water and without crushing or chewing the tablet.
Patients should be advised that the tablet shell may pass through the gastrointestinal tract unchanged.
If necessary, careful dose titration should be taken into account, since the individual response to therapy of different patients may vary. When switching from one type of preparation to another, dose adjustment may be required until a satisfactory response to therapy is achieved. To ensure sustained response to therapy after it has been achieved, especially with sustained release dosage forms, the 90 mg and 120 mg formulations should continue to be branded.
adults
Angina pectoris and arterial hypertension:
The initial dose is one tablet (90 mg or 120 mg) administered twice a day. Patient responses to therapy may vary, and dose requirements may differ significantly between individual patients. In some patients with angina pectoris, the use of high doses of the preparation up to 480 mg per day has proven beneficial, especially in unstable angina. Doses of 360 mg per day may be required to ensure adequate control of blood pressure in patients with arterial hypertension.
Elderly patients and patients with impaired liver or kidney function
The heart rate should be monitored in these patients, if it falls below 50 beats per minute, the dose should be increased.
Angina:
The recommended initial dose is one tablet of the preparation 60 mg in the application 2 times a day. This dose may be increased to one tablet of the preparation 90 mg or 120 mg in the application 2 times a day.
Arterial hypertension:
The initial dose should be one tablet of the preparation 120 mg per day. Dose adjustment may be required to one 90 mg or 120 mg tablet twice daily.
Children.
The safety and efficacy of diltiazem in children have not been established, therefore, the use of the preparation in children is not recommended.
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