Grinterol 250mg 100 capsules — Made in Latvia — Free Delivery

Product description

Grinterol capsules are used for the following indications:

• Dissolution of X-ray negative cholesterol gallstones no more than 15 mm in diameter in patients with a functioning gallbladder, despite the presence of gallstone (s) in it.
• Treatment of biliary reflux gastritis.
• Symptomatic treatment of primary biliary cirrhosis (PBC) in the absence of decompensated liver cirrhosis.
• Treatment of hepatobiliary disorders in cystic fibrosis in children aged 6 to 18 years.

Structure

Active substance: ursodeoxycholic acid;

1 hard capsule contains 250 mg of ursodeoxycholic acid;

Excipients: corn starch, silicon dioxide, magnesium stearate;

Capsule (body and lid): titanium dioxide (E 171), gelatin.

Contraindications

• Hypersensitivity to any substance that is part of the preparation.
• Acute inflammation of the gallbladder or bile ducts.
• Obstruction of the bile ducts (blockage of the common bile duct or bladder duct).
• Frequent episodes of hepatic colic.
• Radiopaque calcified gallbladder stones.
• Violation of the contractility of the gallbladder.
• Poor result of portoenterostomy or lack of adequate biliary outflow in children with biliary atresia.

Mode of application

The capsules should be swallowed whole with a liquid. It is necessary to observe the regularity of reception.

The time of application of 250 mg capsules for primary biliary cirrhosis can be unlimited.

In patients with primary biliary cirrhosis, it is rare at the beginning of treatment that clinical symptoms may worsen, for example, itching may increase. In this case, the treatment should be continued, taking 1 capsule 250 mg per day, after which the dose should be gradually increased (increasing the daily dose by 1 capsule every week) until the prescribed dosage regimen is reached.

Application features

Pregnant

Grinterol ® should not be used during pregnancy, unless absolutely necessary.

Children

For use in children aged 6 to 18 years.

Drivers

No effect on the ability to drive or use other machinery was observed.

Overdose

In cases of overdose, diarrhea is possible. Other symptoms of overdose are unlikely, since the absorption of ursodeoxycholic acid decreases with increasing dose, and therefore most of it is excreted in the faeces.

If diarrhea occurs, the dose should be reduced; if diarrhea persists, treatment should be discontinued.

There is no need for specific measures. The effects of diarrhea should be treated symptomatically, with fluid and electrolyte balance restored.

Side effects

From the gastrointestinal tract. In clinical studies, there have been frequent reports of pasty stools or diarrhea with prolonged treatment with ursodeoxycholic acid.

From the hepatobiliary system. Calcification of gallstones is very rare during treatment with ursodeoxycholic acid.

Hypersensitivity reactions. Allergic reactions, including rash, urticaria, are very rare.

Interaction

Extragenic hormones, as well as preparations to reduce the concentration of cholesterol in the blood, can increase the secretion of cholesterol by the liver, and thus contribute to the formation of gallstones, is the opposite effect of ursodeoxycholic acid used to dissolve them.

Storage conditions

Store in its original packaging at a temperature not exceeding 30 ° C.

Keep out of the reach of children.

Shelf life is 4 years.

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