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    3. Ketilept Retard 50mg 60 long-acting tablets — Made in Hungary — Free Delivery

    Ketilept Retard 50mg 60 long-acting tablets — Made in Hungary — Free Delivery


    Brand: EGIS
    Product Code: Ketilept Retard 50mg
    Availability: In Stock
    $28.81
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    Product description 

    Ketilept® Retard tablets are indicated for the treatment of:
    • Schizophrenia, including prevention of relapse in patients with stable schizophrenia who received maintenance therapy with quetiapine;

    Bipolar disorder, in particular:

    • for the treatment of moderate and severe manic episodes in bipolar disorder;
    • for the treatment of severe depressive episodes in bipolar disorder;
    • for the prevention of relapse of the disease in patients with bipolar disorder, in patients with manic or depressive episodes, in which quetiapine is effective.
    As adjunctive therapy for major depressive episodes in patients with major depressive disorder (SID) who have a suboptimal response to antidepressant monotherapy. Before starting therapy, the doctor should carefully study the safety profile of Ketilept® retard.

    Compound

    Active ingredient: quetiapine;
    1 long-acting film-coated tablet contains 57.56 mg, 172.680 mg, 230.24 mg, 345.36 mg 460.48 mg quetiapine fumarate (corresponding to 50 mg, 150 mg, 200 mg, 300 mg or 400 mg quetiapine );
    Excipients: methacrylate copolymer (type A), lactose (spray dried SD 250), crystalline maltose (Advantose 100), talc, magnesium stearate, vegetable;
    Shell composition: methacrylate copolymer (type A), triethyl citrate (Citrofol).

    Contraindications

    hypersensitivity to the components of the preparation;
    concomitant use of inhibitors of cytochrome P450 3A4, such as inhibitors of HIV protease, azole-containing antifungals, erythromycin, clarithromycin and nefazodone.

    Mode of application

    There are different dosing regimens for each indication. It should be ensured that the patient is prescribed a dosage that is appropriate for their condition. The dose of the preparation and the duration of the course of treatment is determined by the doctor individually for each patient, depending on the indications and severity of the disease. For oral use. The preparation can be taken regardless of the meal. Tablets should be swallowed whole, without breaking, chewing or crushing them.

    Application features

    pregnant
    During pregnancy, the preparation can be prescribed only if the expected benefit outweighs the potential risk.
    Children
    The preparation is not recommended for use in children due to the lack of data supporting its use in this age group.
    Drivers
    Patients are not recommended to drive a car or other mechanisms until individual sensitivity to such effects is determined.

    Overdose

    In general, the symptoms reported were due to an increase in the known pharmacological effects of the preparation, such as drowsiness and sedation, tachycardia and hypotension. There is no specific antidote for quetiapine. In severe cases, consideration should be given to the use of multidirectional measures and intensive care, including the restoration and maintenance of airway patency, provision of adequate oxygenation and ventilation of the lungs, monitoring and support of the cardiovascular system. Published reports describe cases of elimination of serious central nervous system (CNS) reactions, including coma and delirium, with intravenous administration of physostigmine (1-2 mg) under continuous ECG monitoring.

    Side effects

    When taking quetiapine, the following adverse reactions were most often reported: drowsiness, dizziness, dry mouth, headache, withdrawal symptoms (in case of discontinuation of the preparation), increase in serum triglycerides, increase in total cholesterol (especially LDL cholesterol), decrease in blood HDL cholesterol, weight gain, decreased hemoglobin and extrapyramidal symptoms.

    Interaction

    The preparation should be used with caution in patients receiving other preparations with anticholinergic (muscarinic) effects.
    Despite the fact that quetiapine primarily acts on the central nervous system (CNS), Quetixol should be used with caution in combination with other preparations that have a similar effect, and with alcohol.
    Concomitant use of cytochrome P450 3A4 inhibitors such as HIV protease inhibitors, azole antifungals, erythromycin, clarithromycin and nefazodone.

    Storage conditions

    Store below 30°C.
    Keep out of the reach of children.
    Shelf life - 3 years.

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