MaxAlgin Teva is a preparation that contains metamizole sodium monohydrate. MaxAlgin Teva is intended for adults and belongs to a group of medicines called pyrazolones.
Treatment of colic (cramping abdominal pain), acute cancer pain and severe post-traumatic and post-operative pain, high fever when other treatments have failed, other acute or prolonged pain when other measures cannot be taken.
1 tablet contains
Analgesic, antipyretic.
Adults: a single dose is 1-2 tablets (500 mg-1000 mg of metamizole), the patient can take the preparation up to 4 times a day at intervals of 6-8 hours, a maximum of 8 tablets which corresponds to 4000 mg of the active substance.
The dosage depends on the severity of the fever or pain and your individual response to medication.
The lowest dose that is effective in relieving fever and pain should be used.
Repeatedly high doses should be avoided when liver or kidney function is impaired due to a reduced elimination rate. Short-term use does not require dose reduction. To date, there is no experience with long-term use.
In debilitated elderly patients and in patients with impaired renal function, the dose should be reduced since the elimination of metamizole products may be prolonged.
The duration of treatment depends on the severity and nature of the disease and should be determined by the attending physician.
Painkillers should not be used for more than 3-5 days without consulting a doctor or dentist.
MaxAlgin Teva is intended for oral administration, the tablet should be taken whole with a sufficient amount of liquid (e.g. a glass of water).
Do not use in children and adolescents.
Do not take if you are allergic (hypersensitive) to any of the ingredients of the preparation.
If you have known intolerance to painkillers (analgesic asthma syndrome or intolerance to painkillers manifested by urticaria and / or angioedema); This applies to patients who experience bronchospasm (sudden narrowing of the lower airways) or other symptoms of a hypersensitivity reaction after exposure to pain relievers suchs as salicylates, paracetamol or other non-opioid analgesics such as indomethacin, diclofenac, ibuprofen or naproxen. .
If the patient is in the last three months of pregnancy.
If you suffer from bone marrow disorders, e.g. after treatment with cytostatics (preparationused to treat cancer).
If you suffer from disorders of blood production (diseases of the haematopoietic system).
If you suffer from acute intermittent hepatic porphyria (an inherited disease with impaired hemoglobin synthesis) as there is a risk of triggering an attack of porphyria.
If you have a genetic deficiency of glucose-6-phosphate dehydrogenase (a birth defect with risk of breakdown of red blood cells).
Store in the original package in order to protect from light.
There are no special recommendations regarding the storage temperature of the preparation.
Keep the preparation out of the sight and reach of children.
MaxAlgin Teva should not be used after the expiry date which is stated on the blister and carton. The expiry date refers to the last day of that month.
Like all medicines, MaxAlgin Teva can cause side effects, although not everybody gets them.
Uncommon side effects (may affect up to 1 in 100 people)
Drop in blood pressure (common symptoms of a severe drop in blood pressure are pallor, tremors, increased heart rate, dizziness, loss of consciousness, nausea).
A purple to dark red skin rash, sometimes with blisters.
Rare side effects (may affect up to 1 in 1,000 people)
Hypersensitivity reactions (anaphylactoid or anaphylactic reactions).
Skin rash.
Reduction in the number of white blood cells in the blood (leukopenia).
Very rare side effects (may affect up to 1 in 10,000 people)
An asthma attack.
Severe reduction in the number of white blood cells.
A sharp deterioration in kidney function.
Extensive blistering of the skin and peeling of the epidermis.
Not known (frequency cannot be estimated from the available data)
Anemia with simultaneous disturbance of the bone marrow, decrease in the number of white and red blood cells and decrease in the number of platelets in the blood.
Heart attack as part of an allergic reaction (Kounis syndrome).
Anaphylactic shock.
Gastrointestinal bleeding has been reported.
Tell your doctor or pharmacist about all the preparations you are taking or have recently taken, and about any preparations you plan to take.
Concomitant use of metamizole may reduce the effect of acetylsalicylic acid on platelets. Therefore, MaxAlgina should be used with caution in patients receiving low-dose acetylsalicylic acid to protect the heart.
Metamizole sodium may decrease blood levels of cyclosporine (a preparation used to suppress the immune system). In case of simultaneous administration, blood levels of ciclosporin should be monitored.
Taking MaxAlgin Teva together with chlorpromazine (a preparation used to treat mental illnesses) may cause a severe drop in body temperature.
Concomitant use of metamizole and methotrexate (a preparation used to treat cancer or some rheumatic diseases) may increase the harmful effects of methotrexate on the haematopoietic process, especially in elderly patients. Therefore, the combination of both preparations should be avoided.
Metamizole can lower the levels of bupropion (used to treat depression or to help you quit smoking). Therefore, it is recommended to exercise caution when using bupropion and MaxAlgin at the same time.
Do not continue taking MaxAlgin Teva if you have any of the following symptoms, which could be a sign of agranulocytosine: fever that does not go away or returns, unexpected deterioration of your general health (chills, sore throat, fever, difficulty swallowing), painful inflammation mucous membranes (especially in the mouth, throat and nose, or on the genitals or around the anus).
If you forget to take a medicine, do not take a double dose to make up for the forgotten dose.
If you experience any of the symptoms of overdose (vomiting, nausea, dizziness, abdominal pain, drowsiness (lethargy), kidney problems including acute kidney failure, loss of consciousness, drop in blood pressure low enough to cause shock, seizures or arrhythmias heart) contact your doctor immediately to start appropriate treatment.
In the event of symptoms such as thrombocytopenia, pancytopenia or agranulocytosis, treatment should be discontinued immediately and the blood count should be checked.
Please tell your doctor that you are taking MaxAlgin Teva before any laboratory tests are performed. Metamizole may influence the results of some tests (e.g. blood serum creatinine, triglycerides, HDL cholesterol or uric acid levels).
After very high doses, excretion of a harmless metabolite (rubazonic acid) can cause the urine to turn red.
Breastfeeding: Metamizole metabolites are excreted in breast milk in significant amounts and a risk to the suckling infant cannot be excluded. Multiple use of metamizole during lactation should be avoided. In the case of a single intake of the preparation, it is recommended to express and discard food for 48 hours after taking the preparation.
This medicine contains 32.7 mg of sodium (the main ingredient of table salt) in each tablet. This is equivalent to 1.64% of the recommended maximum daily diet for an adult.
Pregnancy: the preparation should not be used in the first and third trimesters of pregnancy. In the second trimester, the preparation should be used only after consulting a doctor or pharmacist.
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