Meldonium, solution for injection 100mg/ml, 5ml x 10 ampoules — Made in Ukraine — Free Delivery

Product description

Solution for injection Meldonium is indicated in the complex therapy of diseases:

• diseases of the heart and vascular system: stable exertional angina, chronic heart failure (NYHA I-III and functional class), cardiomyopathy, functional disorders of the heart and vascular system;
• acute and chronic ischemic disorders of cerebral circulation;
• decreased performance, physical and psycho-emotional overstrain;
• during the recovery period after cerebrovascular disorders, head trauma and encephalitis.

Composition

Active substance: meldonium;

1 ml meldonium (3- (2,2,2-trimethylhydrazinium) propionate dihydrate) 100 mg;

5 ml of solution (1 ampoule) contain meldonium (3- (2,2,2-trimethylhydrazinium) propionate dihydrate) 500 mg;

Excipients: sodium hydroxide, diluted hydrochloric acid, water for injection.

Contraindications

hypersensitivity to meldonium and / or any of the excipients of the preparation;

increased intracranial pressure (with impaired venous outflow, intracranial tumors);

severe hepatic and / or renal impairment (insufficient data on the safety of use).

Mode of application

Intravenously. The use of the preparation does not provide for special preparation before administration.

Due to the possible stimulating effect, the preparation is recommended to be used in the first half of the day.

Adults. The dose is 500-1000 mg (5-10 ml) into a vein, it is administered at one time or divided into two doses. The duration of treatment is usually 10-14 days, after which the treatment is continued with an oral dosage form. The duration of the course of treatment is 4-6 weeks. The course of treatment can be repeated 2-3 times a year.

Elderly patients. Elderly patients with impaired liver and / or kidney function may reduce the dose of meldonium.

Patients with impaired renal function. Since the preparation is excreted by the body by the kidneys, a lower dose of meldonium should be used in patients with mild to moderate renal impairment.

Patients with impaired liver function. Patients with mild to moderate hepatic impairment should use a lower dose of meldonium.

Application features

Pregnant

Contraindicated.

Children

Contraindicated.

Overdose

No cases of meldonium overdose have been reported. The preparation is low-toxic and does not cause threatening side effects.

With low blood pressure, headache, dizziness, tachycardia, weakness are possible. Treatment is symptomatic.

In case of severe overdose, it is necessary to monitor the functions of the liver and kidneys.

Hemodialysis is not essential in case of an overdose of meldonium due to the pronounced binding to blood proteins.

Side effects

• headache;
• allergic reactions;
• dispersion;
• dyslipidemia;
• increased levels of C-reactive protein.

Interaction

Meldonium can be used together with long-acting nitrates and other antianginal preparations (stable angina pectoris), cardiac glycosides and diuretic preparations (heart failure). It can also be combined with anticoagulants, antiplatelet agents, antiarrhythmics and other preparations that improve microcirculation.

Meldonium can enhance the effect of preparations containing glyceryl trinitrate, nifedipine, beta-blockers and other antihypertensive preparations and peripheral vasodilators.

Storage conditions

Store at a temperature not exceeding 25 ° C in its original packaging. Do not freeze.

Keep out of the reach of children.

Shelf life is 2 years.

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