Decongestants and other topical preparations for diseases of the nasal cavity. Sympathomimetics.
Vasoconstrictor, decongestant. Stimulates? 2-adrenergic receptors of the sympathetic nervous system. When applied intranasally, it causes narrowing of the arterioles of the nasal mucosa, reducing its edema and hyperemia, reduces exudation, restores nasal breathing, and reduces the severity of rhinorrhea. Reduces swelling of the mucous membrane of the Eustachian tubes, improving drainage in Eustachitis and otitis media.
The effect of the preparation is detected 15 minutes after application. Duration of action - 10 - 12 hours.
When applied topically, oxymetazoline is almost not subject to systemic absorption, therefore its concentration in blood plasma is negligible. It is excreted mainly unchanged by the kidneys and intestines.
Acute respiratory illness with nasal congestion. Allergic rhinitis. Vasomotor rhinitis. To restore drainage and nasal breathing in diseases of the paranasal sinuses, eustachitis, otitis media. To eliminate edema before diagnostic manipulations in the nasal passages.
active substance: oxymetazoline;
1 ml of solution contains oxymetazoline hydrochloride 0.5 mg;
excipients: benzalkonium chloride, racemic camphor, racemic menthol, eucalyptol, edetate disodium, propylene glycol, sodium dihydrogen phosphate dihydrate, sodium hydroxide or concentrated hydrochloric acid, purified water.
Hypersensitivity to the components of the preparation. Atrophic rhinitis; the use of monoamine oxidase inhibitors and other preparations that increase blood pressure; increased intraocular pressure, especially with closed-angle glaucoma; severe forms of cardiovascular diseases (arterial hypertension, angina pectoris); pheochromocytoma; metabolic disorders (hyperthyroidism, diabetes). During pregnancy and breastfeeding. Children under 6 years of age.
Appropriate safety precautions for use.
Long-term use and preparation overdose should be avoided. Prolonged use of a decongestant can weaken its effect. Abuse of this preparation can cause mucosal atrophy and reactive hyperemia with rhinitis medicamentosa, as well as damage to the mucous epithelium and inhibition of epithelial activity. Doses higher than recommended should be used only under medical supervision.
Application during pregnancy or lactation.
The preparation is contraindicated during pregnancy. If it is necessary to use the preparation, breastfeeding should be discontinued.
The ability to influence the reaction rate when driving or operating other mechanisms.
After prolonged use of the preparation in doses exceeding the recommended ones, a general effect on the cardiovascular system cannot be ruled out. In such cases, the ability to drive a vehicle may be impaired.
Children.
Do not use the preparation in children under 6 years of age.
Method of administration and dosage.
Adults and children over 12 years of age are prescribed 1 injection into each nostril 2 to 3 times a day; children aged 6 to 12 years - 1 injection into each nostril 2 times a day. The course of treatment is no more than 5 - 7 days.
The nozzle of the vial is inserted into each nasal passage and sharply pressed on the vial 1 time during inhalation.
Symptoms: constriction of the pupils, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, collapse, vascular insufficiency, arterial hypertension, respiratory distress, pulmonary edema, cardiac arrest.
In addition, mental disorders may occur, as well as depression of the functions of the central nervous system, accompanied by drowsiness, a decrease in body temperature, bradycardia, arterial hypotension, respiratory arrest and the possible development of coma.
Treatment: gastric lavage, intake of activated carbon, ventilation of the lungs. With a decrease in blood pressure, it is necessary to use phentolamine. You should not take vasopressor preparations. Anticonvulsant therapy is indicated if necessary.
Sometimes - burning or dryness of the nasal membranes, sneezing. Rarely - a feeling of severe nasal congestion (reactive hyperemia). Multiple overdose with local nasal application sometimes leads to systemic sympathomimetic effects such as accelerated heart rate (tachycardia) and increased blood pressure. Very rarely - anxiety, insomnia, fatigue, headache, nausea. Prolonged continuous use of vasoconstrictor preparations can lead to tachyphylaxis, atrophy of the nasal mucosa and reverse edema of the nasal mucosa (rhinitis medicamentosa).
Interaction with other medicinal products and other types of interactions.
With the simultaneous use of MAO blockers and tricyclic antidepressants, an increase in blood pressure is possible.
Previous use of timolol in the form of eye drops may reduce the vasoconstrictor effect of the preparation.
The simultaneous use of other vasoconstrictor preparations increases the risk of side effects.
2 years.
Store in a dark place at a temperature of 15 ° C to 25 ° C.
Keep out of the reach of children.
There are no reviews for this product.