Nasoferon - antiviral, antimicrobial, anti-inflammatory, immunomodulatory, antiproliferative agent. the biological effect of interferon is characterized by the following effects: antiviral - inhibits the replication of viruses (adenoviruses, influenza viruses) due to an inhibitory effect on the processes of transcription and translation; antiproliferative - inhibits the multiplication of cells (most DNA and RNA viruses). Interferon initiates the synthesis of a specific enzyme, protein kinase, which prevents translation due to phosphorylation of one of the initiating factors of this process; activates a specific ribonuclease that damages the viral matrix RNA. the effects of interferon also include: stimulation of the production of other cytokines, induction of specific enzymes, inhibition of cell proliferation, immunomodulation (increased phagocytic activity of macrophages and specific cytotoxicity of lymphocytes relative to target cells). interferon is a mediator of immunity, has a pronounced tissue specificity, protects the body from pathogens of infectious diseases.
Pharmacokinetics. Has not been investigated.
Prevention and treatment for ARVI in children aged 1 month (for nasal spray - from 1 year) and adults:
At the first signs of ARVI (within 5 days):
* 1 spray dose = 1 short press on the dispenser.
For the prevention of respiratory viral infections. Upon contact with the patient and hypothermia - in accordance with the age dosage 2 times within 5-7 days. If necessary, preventive courses are repeated. With a single contact, one instillation (injection) is sufficient.
With a seasonal increase in morbidity - in accordance with the age dosage, once in the morning with an interval of 1-2 days.
Hypersensitivity to interferon alfa-2b and other components of the preparation, a history of severe allergic diseases. the period of pregnancy or lactation.
In isolated cases - a skin rash.
Nazoferon nasal spray. the preparation contains methyl parahydroxybenzoate, which can cause allergic reactions, including delayed ones, in exceptional cases - bronchospasm.
Do not use the preparation in case of violation of the integrity and labeling of the package, when the physical properties (color or transparency of the liquid) change and after the expiration date.
Individual use is recommended to prevent the spread of infection.
The procedure for using a nasal spray:
1. Remove the protective cap from the bottle.
2. Activate the sprayer by pressing (test spray).
3. Being in an upright position, place the end of the nozzle alternately in each nasal passage and press the dosing pump.
4. After use, close the bottle with a cap.
Children. Use in children from 1 year of age.
Nazoferon nasal drops. The preparation should be injected into each nasal passage.
Before using the preparation, it is necessary to take a position lying on your back or sitting, tilt your head back slightly and turn towards the nasal passage into which the drops will be instilled, and, without touching the bottle dropper to the inner walls of the nose, drip the preparation. Immediately after instillation, to evenly distribute the preparation over the nasal mucosa, it is recommended to massage the wings of the nose with your fingers from the outside for several minutes.
The use of drops for children should be carried out under the supervision of adults.
The preparation contains methyl parahydroxybenzoate, which can cause allergic reactions, including delayed ones, in exceptional cases - bronchospasm.
Do not use the preparation in case of violation of the integrity and labeling of the package, when the physical properties (color or transparency of the liquid) change and after the expiration date.
To avoid the spread of infection, individual use is recommended.
Avoid getting the preparation on the mucous membrane of the eyes.
The procedure for using nasal drops in a bottle sealed with a dropper:
1. Remove the protective cap from the bottle.
2. Turn the bottle with the nozzle down and before the first application of the drops, make a few test presses on the dosing pump.
3. Place the tip of the nozzle alternately in each nasal passage and press the dosing pump the required number of times in accordance with the dosage.
4. After use, close the bottle with a cap.
Children. Use in children from 1 month of age.
Nazoferon nasal spray / nasal drops
Use during pregnancy and lactation. The use is contraindicated.
The ability to influence the reaction rate when driving or working with other mechanisms. Does not affect.
The simultaneous use of intranasal vasoconstrictor preparations is not recommended, as this leads to dryness of the nasal mucosa.
Has not been investigated.
In the dark place at a temperature of 2-8 ° C. shelf life after opening the bottle - 10 days.
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