• Home

  • HEALTH CARE

  • HEALTHY LIFESTYLE

  • HYGIENE

  • COSMETICS

  • FOR HIM

  • PREGNANCY AND MOTHERHOOD

  • CHILD

    2. HEALTH CARE
    3. Neuromax injection 2ml x 10 ampoules — Made in Ukraine — Free Delivery

    Neuromax injection 2ml x 10 ampoules — Made in Ukraine — Free Delivery


    Brand: Pharmaceutical company "Zdorovye"
    Product Code: Neuromax
    Availability: In Stock
    $26.50
    Add to Cart

    Product description

    The action of the preparation is due to the action of its active components.
    The neurotropic B vitamins have a beneficial effect on inflammatory and degenerative diseases of the nerves and locomotor system. They are used to eliminate deficiency conditions, and in large doses they have an analgesic effect, improve blood circulation, normalize the functioning of the nervous system and the process of hematopoiesis.
    Vitamin B 1 (thiamine) is a very important active ingredient. In the body, vitamin 1 is phosphorylated to form biologically active thiamine diphosphate (cocarboxylase) and thiamine triphosphate (TTP).
    Thiamine diphosphate as a coenzyme takes part in the process of carbohydrate metabolism, which are of decisive importance in the metabolic processes of nervous tissue, affect the conduction of nerve impulses in synapses. With a deficiency of vitamin B 1 in the tissues, the accumulation of metabolites occurs, primarily lactic and pyruvic acid, which leads to various pathological conditions and disorders of the nervous system.
    Vitamin B 6 (pyridoxine) in phosphorylated form (pyridoxal-5-phosphate, PALP) is a coenzyme of a number of enzymes that interact in the overall non-oxidative metabolism of amino acids. Through decarboxylation, they participate in the formation of physiologically active amines (adrenaline, histamine, serotonin, dopamine, tyramine), through transamination - to anabolic and catabolic metabolic processes (for example, glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, γ-amino acid metabolism) also to various processes of cleavage and synthesis of amino acids. Vitamin B 6 acts on 4 different tryptophan metabolism. In the process of hemoglobin synthesis, vitamin B 6 catalyzes the formation of a-amino-b-ketoadinic acid.
    Vitamin B 12 (cyanocobalamin) is essential for the processes of cellular metabolism. It affects the function of hematopoiesis (external antianemic factor), participates in the formation of choline, methionine, creatinine, nucleic acids, and has an analgesic effect.
    Pharmacokinetics. After parenteral administration, thiamine is distributed in the body. Approximately 1 mg of thiamine is broken down daily. Metabolites are excreted in the urine. Dephosphorylation occurs in the kidneys. The biological half-life of thiamine is 0.35 hours. The accumulation of thiamine in the body does not occur due to the limited dissolution in fats.
    Vitamin B 6 is phosphorylated and oxidized to pyridoxal 5-phosphate. In blood plasma, pyridoxal 5-phosphate and pyridoxal bind to albumin. The form transported is pyridoxal. For passage through the cell membrane, pyridoxal-5-phosphate bound to albumin is hydrolyzed by alkaline phosphatase to pyridoxal.
    Vitamin B 12 after parenteral administration forms transport protein complexes that are rapidly absorbed by the liver, bone marrow and other proliferative organs. Vitamin B 12 enters bile and takes part in the intestinal-hepatic circulation. Vitamin B 12 passes through the placenta.

    Indications

    Neurological diseases of various origins: neuritis, neuralgia, polyneuropathy (diabetic, alcoholic), radicular syndrome, retrobulbar neuritis, facial nerve damage.

    Contraindications

    Hypersensitivity to the components of the preparation; acute violation of cardiac conduction; acute form of decompensated heart failure.
    Vitamin B 1 is contraindicated in case of allergic reactions.
    Vitamin B 6 is contraindicated for use in case of gastric ulcer and duodenal ulcer in the acute stage (since it is possible to increase the acidity of gastric juice).
    Vitamin B 12 is contraindicated for use in erythremia, erythrocytosis, thromboembolism.
    Lidocaine. Hypersensitivity to lidocaine or other amide local anesthetics, a history of epileptiform seizures to lidocaine, severe bradycardia, severe arterial hypotension, cardiogenic shock, severe forms of chronic heart failure (II-III degree), sick sinus syndrome, Wolf-Parkinson syndrome White, Adams-Stokes syndrome, AV (AV) blockade of II and III degrees, hypovolemia, severe liver / kidney dysfunction, porphyria, myasthenia gravis.

    Method of administration and dosage

    For an introduction.
    Before using a preparation containing lidocaine, it is imperative to conduct a skin test for increased individual sensitivity to the preparation, as evidenced by edema and redness of the injection site.
    In severe (acute) cases, treatment should be started with 2 ml of solution intramuscularly 1 time per day until acute symptoms are relieved. To continue treatment, prescribe 2 ml (1 injection) 2-3 times a week. The course of treatment lasts at least 1 month.
    The injection should be done in the upper outer quadrant of the gluteus maximus.
    To maintain or continue the therapeutic course of injections or to prevent relapse, the preparation Neuromax, film-coated tablets, is recommended.

    Overdose

    Vitamin B 1 has a wide therapeutic range. Very high doses (more than 10 g) exhibit a curariform effect, suppressing the conduction of nerve impulses.
    Vitamin B 6 has a very low toxicity.
    Excessive use of vitamin 6 in doses of more than 1 g per day for several months can lead to neurotoxic effects.
    Neuropathies with ataxia and sensory disorders, cerebral convulsions with changes in the EEG, as well as, in some cases, hypochromic anemia and seborrheic dermatitis have been described after administration of more than 2 g per day.
    Vitamin B 12: after parenteral administration (in rare cases - after oral administration) doses of the preparation higher than recommended, allergic reactions, eczematous skin disorders and a benign form of acne were observed.
    With long-term use in high doses, it is possible to disrupt the activity of liver enzymes, pain in the region of the heart, hypercoagulation.
    Treatment: symptomatic therapy.
    Lidocaine. Symptoms: psychomotor agitation, dizziness, general weakness, decreased blood pressure, tremor, visual impairment, tonic-clonic seizures, coma, collapse, possible AV blockade, CNS depression, respiratory arrest. The first symptoms of overdose in healthy people occur when the concentration of lidocaine in the blood is more than 0.006 mg / kg, convulsions - at 0.01 mg / kg.
    Treatment: discontinuation of preparation administration, oxygen therapy, anticonvulsants, vasoconstrictors (norepinephrine, mezaton), with bradycardia - anticholinergics (0.5-1 mg atropine). It is possible to carry out intubation, artificial ventilation of the lungs, resuscitation measures. Dialysis is ineffective.

    Compound

    active ingredients: 1 ml of pyridoxine hydrochloride 50 mg, thiamine hydrochloride 50 mg, cyanocobalamin 0.5 mg
    excipients: lidocaine hydrochloride, potassium hexacyanoferrate, sodium polyphosphate, benzyl alcohol, sodium hydroxide, water for injection.

    Storage conditions

    Store in original packaging at temperatures between 2 ° and 8 ° C.
    Keep out of the reach of children.
    Shelf life is 2 years.

    There are no reviews for this product.
    VEV Healthcare Store © 2017