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    3. Noobut IC 100, powder for oral solution 500 mg/dose, 2.5g x 10 sachets — Made in Ukraine — Free Delivery

    Noobut IC 100, powder for oral solution 500 mg/dose, 2.5g x 10 sachets — Made in Ukraine — Free Delivery


    Brand: InterChem
    Product Code: Noobut IC 100
    Availability: In Stock
    $34.58
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    Pharmacological properties

    Pharmacodynamics. Phenibut is a phenyl derivative of γ-aminobutyric acid. improves gamma-mediated transmission of nerve impulses to the central nervous system (directly affects the gamma receptors of the central nervous system), improves the functional state of the brain by normalizing tissue metabolism and affecting cerebral circulation. dominant is its antihypoxic and antiamnestic effect. stimulates learning processes, improves memory, increases physical and mental performance. has a tranquilizing property: eliminates psycho-emotional stress, anxiety, fear, emotional lability, irritability, improves sleep, lengthens and enhances the effect of hypnotics, narcotic, neuroleptic and anticonvulsants. in contrast to the action of tranquilizers under the influence of noobut ​​ic, psychological indicators (attention, memory, speed and accuracy of sensory-motor reactions) are improved.
    It lengthens the latency period and shortens the duration and severity of nystagmus, has an antiepileptic effect. Does not affect cholinergic receptors and adrenergic receptors. Significantly reduces the manifestations of asthenia and vaso-vegetative symptoms, including headache, a feeling of heaviness in the head. In patients with asthenia and in emotionally labile patients, from the very first days of preparation therapy, well-being improves, interest and initiative increase, motivation for vigorous activity without sedation or excitement. It was found that Noobut ​​IC, used after traumatic brain injury, increases the number of mitochondria perifocally and improves the bioenergetics of the brain. In the presence of lesions of the heart and stomach, Noobut ​​IC normalizes LPO processes.
    Pharmacokinetics. The preparation is well absorbed after oral administration and penetrates well into all tissues of the body, passes through the BBB. Distribution in the liver and kidneys is close to uniform, and in the brain and blood it is below uniform. After 3 hours, a noticeable amount of the injected phenibut is detected in the urine, at the same time, the concentration in the brain tissues does not decrease, it is determined in the brain after another 6 hours. The next day, phenibut can only be detected in urine; it is also noted in the urine 2 days after ingestion, but this amount is only 5% of the administered dose. The greatest binding of phenibut occurs in the liver (80%), it is not specific. No cumulation was observed upon repeated administration.

    Indications

    Asthenic and anxious-neurotic states (emotional lability, memory impairment, decreased concentration of attention), anxiety, fear, anxiety, obsessive-compulsive disorder.
    In children, stuttering, enuresis, tics.
    The elderly have insomnia, nighttime restlessness.
    Meniere's disease, dizziness associated with dysfunction of the vestibular apparatus, prevention of motion sickness.
    Prevention of stress, before surgery or painful diagnostic tests.
    As an adjunct in the treatment of withdrawal symptoms in alcoholism.

    Application

    Noobut ​​ic tablets should be taken orally before meals.
    Adults and children over the age of 14 should be prescribed 250-500 mg 3 times a day. If necessary, the daily dose can be increased to 2.5 g (2500 mg).
    For children aged 3-4 years, prescribe 1 tablet (100 mg) 2 times a day, 5-6 years old - 1 tablet (100 mg) 3 times a day, 7-10 years old - 2 tablets (100 mg) 2 times a day, 11-14 years old - 2 tablets (100 mg) 3 times a day.
    Higher single doses: for children under 6 years old - 100 mg, 7-10 years old - 200 mg, 11-14 years old - 300 mg, for adults and children over the age of 14 years - 750 mg, for elderly patients - 500 mg. The course of treatment is 2-6 weeks.
    Noobut ​​IC can be combined with other psychotropic preparations, this increases its effectiveness (see INTERACTIONS).
    To relieve alcohol withdrawal syndrome Noobut ​​IC in the first days of treatment, prescribe 250-500 mg 3 times a day and 750 mg at night with a gradual decrease in the daily dose to the usual for adults.
    To eliminate dizziness with dysfunction of the vestibular analyzer of infectious origin (otogenic labyrinthitis) and Meniere's disease during an exacerbation of Noobut ​​IC, prescribe 750 mg 3 times a day for 5-7 days, with a decrease in the severity of vestibular disorders - 250-500 mg 3 times day for 5-7 days, then 250 mg 1 time per day for 5 days. With a relatively mild course of diseases, Noobut ​​IC should be used 250 mg 2 times a day for 5-7 days, then 250 mg once a day for 7-10 days.
    To eliminate dizziness with dysfunction of the vestibular analyzer of vascular and traumatic genesis, Noobut ​​IC prescribe 250 mg 3 times a day for 12 days.
    For the prevention of motion sickness in the conditions of sea navigation, it is prescribed in a dose of 250-500 mg once 1 hour before the expected start of rolling or when the first symptoms of seasickness appear. The effect of Noobut ​​IC is enhanced with an increase in the dose of the preparation. In the presence of severe manifestations of seasickness (vomiting, nausea), the use of the preparation is ineffective even at a dose of 750-1000 mg.
    For the prevention of air sickness, the preparation should be used once in a dose of 250–500 mg 1 hour before the flight.
    If one or more doses have been missed, you should continue taking the previously prescribed doses. If the patient's health worsens, it is necessary to consult a doctor.
    Preparation Noobut ​​IC 100. Dissolve the contents of the sachet in 0.5 cups of boiled water and take orally before meals. The course of treatment is 2-6 weeks.
    Children aged 3-4 years are prescribed 100 mg 2 times a day; 5-6 years - 100 mg 3 times a day; 7-10 years old - 200 mg 2 times a day; 11-14 years old - 200 mg 3 times a day.
    Children over the age of 14 are advised to prescribe Noobut ​​IC in the form of 250 mg tablets.
    The maximum single dose for children under 6 years old is 100 mg, 7-10 years old - 200 mg, 11-14 years old - 300 mg.
    To prevent motion sickness, you should take a single dose of Noobut ​​IC 100 1 hour before traveling by sea, land or air.
    Noobut ​​IC 100 / Noobut ​​IC 500 can be combined with other psychotropic preparations, which increases its effectiveness (see INTERACTIONS).
    For relief of alcohol withdrawal syndrome in the first days of treatment, 500 mg is prescribed 2-3 times during the day and 500 mg at night, with a gradual decrease in the daily dose to the usual for adults.
    If the next dose was not taken one or more times in time, then the course of treatment should be continued according to the previously prescribed doses.
    The preparation Noobut ​​IC 500 is prescribed 500 mg 1-3 times a day. If necessary, the daily dose can be increased to 2.5 g (5 sachets).
    For the treatment of dizziness with dysfunction of the vestibular analyzer of infectious origin (otogenic labyrinthitis) and Meniere's disease, the preparation is prescribed during an exacerbation of 500 mg 4 times a day for 5-7 days, with a decrease in the severity of vestibular disorders - 500 mg 2-3 times a day within 5-7 days, and then - 500 mg 1 time per day for 5 days. With a relatively mild course of diseases, the preparation is used at 500 mg 1 time per day for 5-7 days, and then - 100 mg 2-3 times a day for 7-10 days (using Noobut ​​IC 100).
    For the treatment of dizziness with dysfunction of the vestibular analyzer of vascular and traumatic genesis, 500 mg is prescribed 1-2 times a day for 12 days.
    For the treatment of men with erectile dysfunction of psychogenic and mixed genesis - 500 mg once a day. The course of treatment is 21-28 days.
    For the prevention of motion sickness in the conditions of sea navigation, it is prescribed once in a dose of 500 mg 1 hour before the expected onset of motion sickness or when the first symptoms of motion sickness appear.
    With an increase in the dose of the preparation, the effectiveness of Noobut ​​IC 500 as a remedy for motion sickness increases. In the presence of severe manifestations of seasickness (vomiting, etc.), the use of the preparation Noobut ​​IC 500 orally is ineffective even in doses of 1000 mg.
    For the prevention of air sickness, the preparation  is prescribed once in a dose of 500 mg 1 hour before the flight.
    If the next dose was not taken one or more times in time, then the course of treatment should be continued according to the previously prescribed doses.

    Contraindications

    Hypersensitivity to the components of the preparation, acute renal failure.

    Side effects

    From the nervous system: drowsiness (at the beginning of treatment), headache, dizziness (in doses above 2000 mg / day, with a decrease in the dose, the severity of side effects decreases).
    From the gastrointestinal tract: nausea (at the beginning of treatment), vomiting, diarrhea, pain in the epigastric region.
    From the liver and biliary tract: hepatotoxicity (with prolonged use of high doses).
    From the immune system: allergic reactions, including rash, itching, hives, redness of the skin.
    Mental disorders: emotional lability, sleep disturbance (these side reactions can be noted in children if the recommendations of the instructions for the medical use of the preparation are not followed).
    In the event of adverse reactions, you should seek the advice of a doctor.

    Special instructions

    Caution should be exercised in patients with digestive tract pathology due to the irritating effect of phenibut. such patients should be given lower doses. with prolonged use, the cellular composition of the blood, indicators of liver function should be monitored.
    The preparation Noobut ​​IC in the form of tablets contains lactose, therefore it should not be prescribed to patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.
    When using Noobut ​​IC 100 in children with digestive tract pathology, care should be taken due to the irritating effect of the preparation. These children should be given lower doses.
    In the case of prolonged use, it is necessary to monitor the cellular composition of the blood, indicators of liver function.
    1 sachet of the preparation contains 1.5 g of isomalt (E953), therefore, patients with established intolerance to certain sugars should consult a doctor before taking Noobut ​​IC 100.
    Use during pregnancy and lactation. It is not recommended to use the preparation during pregnancy and lactation, since there is insufficient data on the use of the preparation during these periods.
    Children. The preparation can be used in children over the age of 3 years; Noobut ​​IC 500 is not used in children.
    The ability to influence the reaction rate when driving or working with other mechanisms. Patients who experience drowsiness, dizziness or other disorders of the central nervous system during treatment with the preparation should refrain from driving or working with other mechanisms.

    Interactions

    Noobut ​​ic can be combined with psychotropic preparations, reducing the dose of noobut ​​ic and preparations that are used with it.
    Noobut ​​IC enhances and prolongs the effect of hypnotics, narcotic, neuroleptic and antiparkinsonian preparations.

    Overdose

    Phenibut is a low-toxic compound, only in a daily dose of 7-14 g with prolonged use it can be hepatotoxic. the indicated doses significantly exceed the maximum recommended daily dose (750-2500 g). only at a higher dose used eosinophilia and fatty degeneration of the liver were detected. when using phenibut in lower doses, there were no such changes.
    Symptoms: drowsiness, nausea, vomiting, possible development of arterial hypotension, acute renal failure.
    Treatment: gastric lavage. Therapy is symptomatic.
    In case of complications (arterial hypotension, renal failure), take supportive and symptomatic measures.

    Storage conditions

    In original packaging at a temperature not exceeding 25 ° c.

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