The active substance is a standardized extract of ginkgo biloba: 24% heterosides and 6% di- and sesquiterpenes (ginkgolides A, B and C and bilobalide).
In humans, only the pharmacokinetic parameters of terpene fractions are described.
The oral bioavailability of ginkgolides A, B and bilobalide is 80–90%. Cmax is achieved 1–2 hours after taking the preparation. T½ is about 4 hours (bilobalide, ginkgolid A) and 10 hours (ginkgolide B).
These substances in the body do not break down, are almost completely excreted in the urine, a small amount - with feces.
R-oral. Use a dispenser 1 dose = 1 ml of r-ra for oral administration = 40 mg of pure extract.
Assign one dose of a solution 3 times a day with meals.
The dose of the preparation must be diluted in ½ cup of water.
The course of treatment is determined by the doctor individually.
from the digestive system: digestive disorders; dyspepsia; diarrhea; abdominal pain; nausea, vomiting;
from the immune system: hypersensitivity reactions, including angioedema, urticaria, shortness of breath;
on the part of the skin: inflammation of the skin, redness, swelling, rash, itching, eczema;
from the central nervous system: headache, dizziness, syncope (including vasovagal).
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