Pharmacodynamics. the main active ingredient of viprosal ointment is the venom of the common viper (venenum viperae berus), which contains phospholipase, PDE, hyaluronidase and other active substances. viper venom also contains peptides of specific action that cause hemolysis, increase capillary permeability, and affect blood clotting. when applied topically, the viper venom has an irritating and analgesic effect.
Other active ingredients of Viprosal B ointment, which irritate sensitive nerve endings, have a local irritating and analgesic effect. In addition to the analgesic effect of camphor, salicylic acid and turpentine oil also have an antiseptic effect, and salicylic acid has a keratolytic effect.
Pharmacokinetics. The ointment is quickly absorbed and after a few minutes there is a burning sensation, slight hyperemia of the skin and a feeling of warmth. The analgesic effect occurs in 20-30 minutes and lasts 1.5-2 hours.
Anesthetic for external use for joint and muscle pain.
For external use. the ointment is applied to the painful area in a small amount of 5-10 g (1-2 teaspoons) and rubbed into the skin, depending on the intensity of the pain, 1-2 times a day until the pain syndrome disappears. the duration of the course of treatment depends on the nature and severity of the disease.
Elderly patients. There is no evidence that the elderly require a different dosage.
Children. There is no experience with children, therefore the use in this category of patients is not recommended.
Hypersensitivity to any component of the ointment, acetylsalicylic acid or other NSAIDs; ba; whooping cough; tendency to bronchospasm; tendency to seizures; ulcers and other skin conditions; acute pulmonary tuberculosis; cerebral and coronary circulation disorders; a tendency to develop angiospasms; severe impairment of kidney or liver function; fever; general fatigue.
With increased sensitivity of the skin to the components of the ointment, itching, swelling or urticaria may occur during application. allergic reactions may also occur, including contact dermatitis, rashes, redness, burning; headache, dizziness; the occurrence of convulsions caused by camphor is possible.
In this case, it is recommended to stop treatment and wash off the ointment from the skin. These symptoms disappear after stopping treatment.
To prevent side effects, it is recommended to first apply a small amount of the ointment to the skin to determine the sensitivity to the preparation.
The ointment should not be applied to damaged skin. To avoid severe irritation, it is required to ensure that the ointment does not get into the eyes or on the mucous membrane.
A bandage should not be applied to the site of application of the ointment; you can only cover it slightly.
The ointment contains cetostearyl alcohol, which can cause local skin reactions (including contact dermatitis).
Use during pregnancy and lactation. It is contraindicated to use during pregnancy and lactation.
The ability to influence the reaction rate when driving or working with other mechanisms. Does not affect.
Have not studied. Although sufficiently well-controlled interaction trials have not been performed, it is possible that excessive use of topical salicylates may increase the anticoagulant effect of coumarin and antiplatelet preparations. Caution should be exercised in patients receiving coumarin anticoagulants and antiplatelet preparations, including acetylsalicylic acid.
If it gets on the mucous membrane and is applied in too much, the ointment causes severe irritation.
Improper use. Accidental ingestion of the ointment can cause gastrointestinal symptoms such as vomiting and diarrhea. Treatment is symptomatic.
If large amounts of the ointment are accidentally swallowed, symptoms of acute poisoning such as nausea, vomiting, abdominal pain, headache, dizziness, fever / redness, convulsions, respiratory depression and coma may occur.
Observation and treatment of patients with severe gastrointestinal or neurological symptoms of poisoning is symptomatic. Do not induce vomiting.
At a temperature not exceeding 25 ° c. do not store in refrigerator and freezer.
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