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    3. Zolafren 10mg 30 tablets — Made in Poland by Adamed — Free Delivery

    Zolafren 10mg 30 tablets — Made in Poland by Adamed — Free Delivery


    Brand: ADAMED
    Product Code: Zolafren 10mg
    Availability: In Stock
    $40.36
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    Product description

    Zolafren tablets are indicated for:
    • treatment of schizophrenia;
    • maintaining the achieved clinical effect with long-term therapy in patients who have observed a response to initial therapy;
    • treatment of moderate and severe manic episodes;
    • prevention of recurrent seizures in patients with bipolar disorder who have responded positively to olanzapine treatment for mania.

    Compound

    Active ingredient: 1 tablet contains 5 mg or 10 mg of olanzapine;
    Excipients: lactose, microcrystalline cellulose, sodium starch (type A), magnesium stearate;
    Shell: hypromellose (hypromellose), polyethylene glycol (Macrogol) 400, Yellow No.6 Al-Lake dye (E 110), titanium dioxide (E 171), iron oxide yellow (E172), lactose.

    Contraindications

    Hypersensitivity to the active substance or to the auxiliary components of the preparation.
    Known risk of angle-closure glaucoma.

    Mode of application

    Treatment of schizophrenia, manic episodes and prevention of relapse in bipolar disorder. The daily dose to be determined based on clinical status in the range of 5 to 20 mg per day. An increase in the recommended initial dose should be carried out at intervals of at least 24 hours only after a clinical examination. Olanzapine should be used with or without food, as food does not affect the absorption of the preparation. With the abolition of the preparation, the end of therapy should be carried out gradually.

    Application features

    pregnant
    Olanzapine should be used during pregnancy only when the expected results justify the potential risk to the fetus.
    Children
    Olanzapine is not recommended for the treatment of children and adolescents.
    Drivers
    With caution, dizziness and drowsiness are possible.

    Overdose

    Symptoms. Very common (> 10%): tachycardia, agitation/aggression, dysarthria, various extrapyramidal symptoms and decreased level of consciousness, ranging from sedation to coma.
    Other significant complications of overdose are delirium, convulsions, coma, the possibility of neuroleptic malignant syndrome, respiratory depression, aspiration, arterial hypertension or hypotension, cardiac arrhythmias (<2% of overdose cases) and cardiopulmonary shock. Fatal outcomes have been reported with acute overdose at the 450 mg level, but there have been cases of survival after acute overdose after taking 2 g of olanzapine orally.
    Treatment. There is no specific antidote. Preparations that cause vomiting are not recommended. Recommended standard procedures for overdose (for example, gastric lavage, activated charcoal). Co-administration of activated charcoal has been found to reduce oral bioavailability of olanzapine by 50-60%.

    Side effects

    The most common adverse reactions (observed in ≥ 1% of patients) associated with the use of olanzapine in clinical studies were: drowsiness, weight gain, eosinophilia, increased levels of prolactin, cholesterol (cholesterol), glucose and triglycerides in the blood, glycosuria, increased appetite, dizziness, akathisia, parkinsonism, leukopenia, neutropenia, dyskinesia, orthostatic hypotension, anticholinergic effects, transient asymptomatic increase in hepatic transaminases, rash, asthenia, fatigue, hyperthermia, arthralgia, elevated levels of alkaline phosphatase, gammaglutamyltransferase, uric acid, CPK, and edema .

    Interaction

    Caution should be exercised when olanzapine is administered with other preparations known to increase the QTc interval.

    Storage conditions

    Store at a temperature not exceeding 25°C, in the original packaging.
    Keep out of the reach of children.
    Shelf life - 3 years.

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