Acyclovir 800 Stada® tablets are used for the following indications:
Active substance: acyclovir;
1 tablet contains 800 mg acyclovir;
Excipients: microcrystalline cellulose, colloidal silicon dioxide, sodium starch (type A), copolyvidone, magnesium stearate.
Hypersensitivity to acyclovir, valacyclovir or to any other components of the preparation.
The tablet should be taken whole with water. When using high doses of acyclovir, an adequate level of body hydration should be maintained.
Pregnant
There was no increase in the number of congenital defects in children whose mothers used acyclovir during pregnancy, compared with the general population. However, it is necessary to use acyclovir tablets only when the potential benefit of the preparation to the mother outweighs the possible risk to the fetus.
Children
The tablets are used for children with immunodeficiency at the age of 2 years.
Symptoms Acyclovir is only partially absorbed from the gastrointestinal tract. Accidental internal intake of up to 20 g of acyclovir by patients without the occurrence of a toxic effect has been reported. Accidental repeated oral overdose of oral acyclovir over several days causes gastroenterological (such as nausea and vomiting) and neurological symptoms (headache and confusion). In case of an overdose of intravenous acyclovir, the level of serum creatinine and blood urea nitrogen increases, which leads to renal failure. Overdose neurological manifestations can be confusion, hallucinations, agitation, convulsions, and coma.
Treatment. The patient must be carefully examined to identify symptoms of intoxication. Since acyclovir is well removed from the blood by hemodialysis, the latter should be used in case of overdose.
On the part of the blood and lymphatic system: anemia, thrombocytopenia, leukopenia.
From the immune system: anaphylaxis.
Mental and nervous system disorders: headache, dizziness, agitation, confusion, tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, convulsions, drowsiness, encephalopathy, coma.
The above neurological reactions are generally reversible and usually occur in patients with renal insufficiency or other risk factors.
From the respiratory system and chest organs: shortness of breath.
From the digestive system: nausea, vomiting, diarrhea, abdominal pain.
From the hepatobiliary system: a reversible increase in the level of bilirubin and liver enzymes, jaundice, hepatitis.
On the part of the skin and subcutaneous tissue: itching, rash (including photosensitivity), urticaria, frequent diffuse hair loss (since hair loss can be associated with a large number of diseases and preparations, no clear connection with acyclovir has been found), angioedema.
On the part of the kidneys and urinary system: increased levels of urea and blood creatinine, acute renal failure, pain in the kidneys.
Kidney pain can be associated with renal failure and crystalluria.
No clinically important interactions of acyclovir with other preparations have been identified.
Does not require special storage conditions.
Keep out of the reach of children.
The shelf life is 5 years.
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