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Pharmachologic EffectMikardis Plus is an antihypertensive preparation. It is a combination of telmisartan (an angiotensin II receptor antagonist) and hydrochlorothiazide (a thiazide diuretic). The simultaneous use of these components leads to a greater antihypertensive effect than the use of each of..

Pharmacological propertiesPharmacodynamics. Telmisartan is a specific and effective antagonist of angiotensin II receptors (AT1 type). Telmisartan replaces angiotensin II with a very high degree of affinity at the sites of its binding to the at1 receptors responsible for the physiological effects of..