Ascorbic acid 0,05g 2p x 160 tablets — Made in Ukraine — Free Delivery
(Ascorbic acid )
Indication
Prevention and treatment of vitamin c deficiency. ensuring the body's increased need for vitamin C during growth, pregnancy and breastfeeding; with increased physical and mental stress, with infectious diseases and intoxication, hemorrhagic diathesis, in complex therapy with bleeding (nasal, pulmonary, uterine); with radiation sickness, Addison's disease, overdose of anticoagulants, with damage to soft tissues and infected wounds that heal slowly, bone fractures.
Application
Internally after meals.
Adults and children over 14 years old should take 1-2 dragees (50-100 mg) per day for the purpose of prevention, children aged 3-14 years - 1 dragee (50 mg) per day.
Therapeutic doses for children over the age of 14 and for adults are 1-2 dragees (50-100 mg) 3-5 times a day, for children aged 3-7 years - 1-2 dragees (50-100 mg ) 2-3 times a day, at the age of 7-10 years - 2 dragees (100 mg) 2-3 times a day, at the age of 10-14 years - 2-3 dragees (100-150 mg) 2-3 times day.
Pregnant and postpartum women and with a low level of vitamin C in breast milk should take 6 dragees (300 mg) per day for 10-15 days, then for prevention - 2 dragees (100 mg) per day for the entire period of breastfeeding.
The duration of treatment depends on the nature and course of the disease and is determined by the doctor individually.
Contraindication
Hypersensitivity to ascorbic acid or any of the excipients of the preparation, thrombosis, tendency to thrombosis, thrombophlebitis, diabetes, severe kidney disease, urolithiasis (when using 1 g/day), fructose intolerance, glucose-galactose malabsorption syndrome .
Side effects
Gastrointestinal tract: when using 1 g/day - irritation of the mucous membrane of the digestive tract, heartburn, nausea, vomiting, diarrhea.
On the part of the kidneys and urinary system: damage to the glomerular apparatus of the kidneys, crystalluria, formation of urate, cystine and / or oxalate stones in the kidneys and urinary tract.
From the side of the immune system: Quincke's edema, sometimes - anaphylactic shock in the presence of sensitization.
From the side of the skin and subcutaneous tissue: skin rashes, itching, urticaria, eczema.
From the endocrine system: damage to the insular apparatus of the pancreas (hyperglycemia, glucosuria) and disruption of glycogen synthesis up to the development of diabetes.
From the side of the cardiovascular system: arterial hypertension, myocardial dystrophy.
From the blood and lymphatic system: thrombocytosis, hyperprothrombinemia, thrombus formation, erythrocytopenia, neutrophilic leukocytosis; in patients with deficiency of glucose-6-phosphate dehydrogenase of blood cells can cause hemolysis of erythrocytes, hemolytic anemia (in patients with deficiency of glucose-6-phosphate dehydrogenase).
From the side of the nervous system: increased excitability, sleep disturbance, headache, feeling of heat, fatigue.
From the side of metabolism: disturbance of zinc, copper metabolism.
Special instructions
When using the preparation in high doses and for a long time, it is necessary to monitor the function of the kidneys and the level of hell, as well as the function of the pancreas. the preparation should be used with caution in patients with a history of kidney disease.
With urolithiasis, the daily dose of ascorbic acid should not exceed 1 ml
The preparation should not be prescribed in high doses to patients with increased blood coagulation.
Since ascorbic acid increases the absorption of iron, its use in high doses can be dangerous for patients with hemochromatosis, thalassemia, polycythemia, leukemia and sideroblastic anemia. Patients with a high iron content in the body should use the preparation in minimal doses.
Simultaneous use of the medicinal product with an alkaline drink reduces the absorption of ascorbic acid, so you should not drink it with alkaline mineral water. Also, the absorption of ascorbic acid can be disturbed in case of intestinal dyskinesia, enteritis and achilles.
It is used with caution for the treatment of patients with glucose-6-phosphate dehydrogenase deficiency.
Ascorbic acid as a reducing agent can affect the results of various laboratory tests, for example, when determining the blood glucose, bilirubin, transaminase activity, LDH.
Since ascorbic acid has a mild stimulating effect, it is not recommended to use the medicine at the end of the day. Due to the stimulating effect of ascorbic acid on the formation of corticosteroid hormones, when using the preparation in high doses, monitoring of kidney function and blood pressure is required.
Application during pregnancy and lactation. The preparation can be used during pregnancy or breastfeeding in accordance with the dosage recommendations and the doctor's prescription. It is necessary to strictly follow the recommended doses and not to exceed them.
Children. The preparation is used in children older than 3 years.
The ability to influence the speed of reactions when driving vehicles or working with other mechanisms. Does not affect.
Interactions
Ascorbic acid when used orally increases the absorption of penicillin, tetracycline, and iron; promotes the absorption of aluminum in the intestines, which should be taken into account during simultaneous treatment with aluminum-containing antacids.
The simultaneous use of vitamin C and deferoxamine increases the tissue toxicity of iron, especially in the heart muscle, which can lead to decompensation of the circulatory system. Vitamin C can be used only 2 hours after deferoxamine injection.
Long-term use in high doses by persons using disulfiramin inhibits the disulfiram/alcohol reaction.
High doses of the preparation reduce the effectiveness of tricyclic antidepressants, neuroleptics - phenothiazine derivatives, tubular reabsorption of amphetamine, disrupt the excretion of mexiletine by the kidneys, affect the resorption of vitamin B12.
Ascorbic acid increases the total clearance of ethyl alcohol.
The preparation reduces the toxicity of sulfonamide preparations, as well as the effectiveness of heparin and indirect anticoagulants.
Vitamin C increases the excretion of oxalates in the urine, thus increasing the risk of formation of oxalate stones in the urine, increases the risk of crystalluria during treatment with salicylates.
Medicinal products of the quinoline series, calcium chloride, salicylates, and corticosteroids reduce the ascorbic acid depot in the body with long-term use.
Absorption of ascorbic acid decreases with simultaneous use of oral contraceptives, consumption of fruit or vegetable juices, and alkaline drinking.
Overdose
Ascorbic acid is well tolerated. it is a water-soluble vitamin, its excessive amount is excreted in the urine.
Symptoms With long-term use of vitamin C in high doses, it is possible to inhibit the function of the insular apparatus of the pancreas, which requires monitoring of the condition of the latter. Overdose can lead to changes in renal excretion of ascorbic and uric acids during acetylation of urine with the risk of precipitation of oxalate stones.
The use of the preparation in high doses can lead to vomiting, nausea or diarrhea, which disappear after its withdrawal.
Treatment. Symptomatic therapy.
Storage conditions
In the original packaging at a temperature not higher than 25 °C.
Tags: Ascorbic
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