PROCTO-GLYVENOL COMPLEX 300MG 30 TABS - MADE IN IRLANDIA- FREE SHIPPING
US and the Rest of the World: 9 to 20 business days
Description PROCTO-GLYVENOL COMPLEX 300MG 30 TABS - MADE IN IRLANDIA- FREE SHIPPING
PROCTO-GLYVENOL COMPLEX 300MG 30 TABLETS
The dietary supplement for oral use contains a special form of micronized diosmin, hesperidin, as well as butcher's broom extract and vitamin C.
Butcher's broom extract supports proper venous circulation. Vitamin C helps in the proper production of collagen to ensure the proper functioning of blood vessels.
Application:
supplementing the diet with ingredients contained in the product.
Recommended consumption:
1 tablet daily.
Ingredients:
uSMIN Plus (micronized diosmin); bulking agent-cellulose; L-ascorbic acid (vitamin C); maltodextrin; butcher's broom extract; hesperidin; anti-caking agents; polyvinyl-; magnesium salts of fatty acids; glazing agent - hydroxypropyl methylcellulose; anti-caking agent - silicon dioxide; dye-titanium dioxide; anti-caking agent-fatty acids, dye-iron oxides and hydroxides.
1 tablet contains: uSMIN Plus 300 mg, including diosmin 243 mg; vitamin C 80 mg (100% *); butcher's broom extract 50 mg; hesperidin 30 mg.
* RWS-Reference Value of Consumption.
Contraindications:
do not use in case of hypersensitivity to any component of the product. Please consult your doctor during pregnancy and breastfeeding.
Important tips:
Do not exceed the recommended daily dose.A balanced diet and a proper lifestyle are important for the functioning of the human body.
A dietary supplement cannot be used as a substitute (replacement) for a varied diet.
The dietary supplement should be stored out of reach of small children.
The preparation should be stored at room temperature (15-25 degrees Celsius) in a dry place.
Instructions For the use of medicine PROCTO - GLYVENOL
Ingredients:
Active ingredients: tribenoside, lidocaine
hydrochloride. 1 suppository contains tribenoside400 mg, lidocaine
hydrochloride 40 mg.
Inactive ingredients: hard oil #1 Vitepsol
E85, hard oil #2 (Vitepsol W35)
Medication form: rectal suppositories. Main
physical and chemical properties: white-yellow suppositories, smooth, hard,
oilywith slight scent.
Pharmaceutical group: supplements for local
application to treat hemorrhoids and rectal wounds. Other supplements and
combinations. Code ATX, C05A, X03.
Pharmaceutical properties:
Pharma dynamics: Procto – Glyvenol is a
combination drug for local application on external and internal hemorrhoids.
Tribenoside alleviates soreness and promoting wound healing. Tribenoside helps
to relieve inflammation and pain, while also preventing blood clots by
promoting fibrinolysis. It works for hemorrhoids by acting on the epidermal
cells and regulating types of glycoproteins, which helps contribute to the
reconstruction of basement membranes, thereby contributing to the healing
process of the hemorrhoids. Lidocaine hydrochloride is a local anesthetic, and
it can significantly reduce pain by producing a numbing effect. This is
achieved by acting on the neuronal cell membranes so as to prevent the
occurrence of pain signals.
Pharma kinetics: Procto – Glyvenol acts
locally and does not provide systemic action. After rectal insertion,
tribenoside reaches therapeutic concentration at the area of application and
only small amount of this substance penetrates system blood circulation. When
applied rectally tribenoside bioavailability is 30%. Peak plasma concentrations
of 1 mkg/ml of tribenoside are reached 2 hours after rectal administration.
Tribenoside is intensively metabolized in the body and 20-27 % of the dose is excreted in the urine
in the form of metabolites. Lidocaine is quickly absorbed by mucous membrane
and less is absorbed by undamaged health skin. Lidocaine bioavailability is
approximately 50% after rectal application. The drug is quickly metabolized by
liver. 10% of unchanged lidocaine excreted in the urine.
Clinical characteristics:
Usage:topical treatment of external and
internal hemorrhoids
Do not use if: You have ever had
an allergic reaction to this product or any of its ingredients,
.you have intolerance to active
ingredients.
Drug Interactions: Patients using anti
arrhythmic drugs of class I or any other local anesthetics should use this
product carefully due to possible negative effects of lidocaine.
Specific application:
Patients with heart conditions, kidney and
liver disorders should be careful to use Procto-Glyvenol
Due to the content of cetyl alcohol,
Procto-Glyvenol may cause local skin irritation. Some adverse allergic reaction
may appear with a delay due to the content of metilparahydrobensoat and
propilparahydrobensoat. Procto-Glyvenol package includes latex tip which may
also cause allergic reaction. It is recommended to contact your healthcare
provider is symptoms do not improve after 1 week of application or if new
symptoms appear to exclude any possible side effects and complications. In
addition to treating your hemorrhoids with Procto – Glyvenol, it is advised to
keep the anal are in a good state of hygiene, to get sufficient exercise, and
to take whatever measures you can to ensure that
your stools remain soft. Avoid contact with eye. Do not take orally.
Usage during pregnancy or breastfeeding: Procto-Glyvenol
should not be used during 1 trimester of pregnancy. Procto-Glyvenol is safe to
use after 4th month of pregnancy and while breastfeeding following physician
directions and dose considering possible risks for the mother and child.
Usage while operating machinery or driving:
Procto-Glyvenol does not affect or may have minor effect on driving and
operating machinery.
Administration and Dosage: Rectal
application for adults only. Procto-Glyvenol
hemorrhoid suppository is indicated for local use, and should be applied
directly to the affected area (the anus) 1 suppository twice per day (in the
morning and at night). Subsequently the dose can be reduced to once per day. In
all cases, the duration of treatment will be decided upon by the physician
based on how the patient responds to treatment. For internal hemorrhoids use
the tip included in package. Remove protective cap before each use. 30 g of cream is usually enough for 20-30
applications.
Children. This drug should not be used for
children
Overdose:There are no known cases of
overdose. If you exceed recommended dose consult your healthcare provider. In
case of overdose, symptomatic treatment is recommended.
Side effects: Skin: rarely (>1/10,000),
<1/1000) slight discomfort in the area of application, pain, light burning,
rash, itching. Immune system: rarely (>1/10,000) hypersensitivity is
possible such as anaphylactic reaction, angioedema, face swelling. Heart and
cardiovascular: rarely (>1/10,000) cardiovascular disorder
Other: fever
Shelf life: 5 years.
Storage: Store medicines
at room temperature, away from heat and direct light.
Packaging: 5 suppositories in aluminum foil
blister, 2 blisters per box
Manufacturer: Delpharm Huningue, 26 Rue de
la Chapelle, 68330 Huningue, France
Tags: PROCTO-GLYVENOL
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