Fortix, powder for inhalation hard capsules, 12 mcg 60 pcs — Made in Spain — Free Delivery

Long-acting β2-adrenergic receptor agonists are not intended (and insufficient) for the basic therapy of AD. Along with regular treatment with β2-adrenergic receptor agonists in patients with AD, it is necessary to use regular concomitant treatment with inhaled anti-inflammatory preparations (for example, corticosteroids and / or sodium cromoglycate in children) or oral corticosteroids. Before prescribing formoterol, the patient should be assessed to determine whether he is receiving sufficient anti-inflammatory treatment. When control over asthma symptoms is achieved, it is necessary to gradually reduce the dose of formoterol. During the period of dose reduction, the patient's condition should be monitored regularly. The lowest effective dose of formoterol should be used.

Although formoterol can be included in the treatment regimen if inhaled corticosteroids do not provide sufficient control over the symptoms of asthma, treatment with formoterol should not be started during severe exacerbation of asthma or in the event of a significant or acute deterioration of its course.

At the beginning of treatment with formoterol, there is a risk of developing side effects associated with asthma, as well as a worsening of its course. If BA symptoms remain uncontrollable or if the patient becomes worse after inhalation of formoterol, it is necessary to consult a doctor regarding the advisability of continuing treatment.

Anti-inflammatory treatment should not be discontinued after starting therapy with formoterol, even if the severity of the symptoms of the disease decreases. Persistence of symptoms or the need to increase the dose of formoterol to control them usually indicates a worsening of the underlying disease and the need to correct treatment.

Deaths have been reported with excessive use of preparations containing β2-adrenergic receptor agonists, although the exact cause of death is unknown. In several cases, cardiac arrest was the cause of death. Patients should be warned about the importance of strict adherence to dosage recommendations and the inadmissibility of exceeding the maximum dose.

When using β2-adrenergic receptor agonists at doses higher than recommended, an increase in the QT interval on the ECG was noted, which increased the risk of changes in ventricular rhythm.

Dosage limits for patients using formoterol should be carefully evaluated in such cases:

- ischemic heart disease;

- myocardial infarction;

- severe hypertension;

- Heart arythmy;

- severe heart failure.

Treatment with β2-adrenergic agonists can cause potentially severe hypokalemia. Particular care is required in severe asthma, since this effect can be enhanced by concomitant treatment and hypoxia. In this case, it is necessary to control the level of potassium in the blood plasma.

As with other inhaled preparations, the possibility of paradoxical bronchospasm must be considered; in this case, the preparation should be discontinued and an alternative treatment should be prescribed.

Due to the hyperglycemic effect of β2-adrenergic receptor agonists, it is necessary to control the blood glucose level in patients with diabetes mellitus.

Children. Formoterol is not used in children under 6 years of age.

During pregnancy and breastfeeding. The safety of using formoterol during pregnancy and lactation has not been established. The preparation should not be used during pregnancy unless there is another safe alternative. Like other β2-adrenergic receptor agonists, formoterol can delay labor due to its relaxing effect on uterine smooth muscle.

It is not known whether formoterol passes into breast milk. Therefore, in each case, it is necessary to carefully assess the benefits and risks.

The ability to influence the reaction rate when driving and operating other mechanisms. The patient should be warned about the likelihood of deterioration in the ability to drive vehicles and complex mechanisms due to the development of side effects such as tremors or agitation.