Essential N is a preparation used for liver diseases, lipotropic substances. Indications for use - non-alcoholic steatohepatitis, alcoholic steatohepatitis, acute and chronic hepatitis of various etiologies, cirrhosis of the liver, pre- and postoperative treatment during surgery on the liver and biliary tract, psoriasis, radiation syndrome.

active substance: "Essential phospholipids" = EPL-substance (phospholipids from soybeans (93% (3-sn-phosphatidyl)choline), which contain -tocopherol, ethanol 96%);

1 ml of solution contains "Essential phospholipids" = EPL - substance (phospholipids from soybeans (93% (3-sn-phosphatidyl)choline), which contain -tocopherol, ethanol 96%) – 50 mg;

excipients: benzyl alcohol, deoxycholic acid, sodium chloride, sodium hydroxide, riboflavin (E 101), water for injections.

Hypersensitivity to any of the components of the preparation.

Essentiale N should not be prescribed to newborns and premature babies, as the composition of the preparation includes benzyl alcohol.

In some cases, with the use of increased doses of Essentiale H, disturbances from the gastrointestinal tract (diarrhea) are possible.

In isolated cases, hypersensitivity reactions, rashes, itching, urticaria and reactions at the injection site may occur.

Adults and children over 12 years of age are prescribed intravenously slowly 5-10 ml per day, and in severe cases - from 10 to 20 ml per day. 10 ml of the preparation can be administered at one time. If the preparation is administered diluted, it is recommended to use the patient's own blood and dilute the preparation in a ratio of 1:1. Intravenous infusion is usually used for up to 10 days.

It is recommended as early as possible to support (supplement) parenteral therapy by taking Essentiale forte N capsules.

The total course of treatment is 3-6 months.

Psoriasis treatment begins with taking 2 capsules of Essentiale forte H 3 times a day for 2 weeks. After that, 10 intravenous injections of 5 ml with the simultaneous appointment of PUVA therapy are recommended.

After the end of the course of injections, the capsules are resumed and the use of the preparation is continued for 2 months.

Special security measures.

Use only a clear solution.

The preparation is incompatible with electrolyte solutions (physiological sodium chloride solution, Ringer's solution, etc.).

Do not mix in one syringe with other medicinal products.

The preparation should be slowly injected into a vein (intravenously).

Essentiale N solution for intravenous injection should not be injected into the muscles (intramuscularly) as this may cause local irritation.

Caution: Essentiale® N solution for intravenous administration contains 0.6% alcohol (by volume).

When diluting Essentiale N for the preparation of an infusion solution (if it is impossible to use the patient's own blood), electrolyte-free solutions should be used, namely: 5% or 10% glucose solution (in a 1:1 ratio), 5% xylitol solution.

The preparation cannot be administered intramuscularly due to the possible occurrence of local irritation.

Due to the limited amount of clinical research data on the use of pregnant women and due to the presence of benzyl alcohol in the composition, which can pass through the placental barrier, the use of Essentiale H is not recommended during pregnancy and breastfeeding.

The preparation is intended for use by children over 12 years of age, whose body weight is 43 kg or more.

The ability to influence the speed of reaction when driving vehicles or other mechanisms

Not detected.

No reports of overdose have been recorded.

Keep out of the reach of children. Store in the original packaging at a temperature of 2 to 8C.