Iodomarin 100, 100 tablets — Made in Germany — Free Delivery

Pharmacodynamics. Iodomarin is an inorganic iodine preparation, iodine is a vital trace element that is part of the thyroid hormones - thyroxine (t4) and triiodothyronine (t3) and ensures its normal functioning.

When iodides enter the epithelial cells of the thyroid follicles under the influence of the enzyme iodide peroxidase, iodine is oxidized with the formation of elemental iodine. The substance enters into a substitution reaction with the aromatic tyrosine cycle, as a result of which thyronines are formed: the 3,5-iodine derivative (the thyroxine hormone - T4) and the 3-iodine derivative (the triiodothyronine T3 hormone). Thyronines form a complex with the protein thyroglobulin, which is deposited in the colloid of the thyroid follicle and remains in this state for several days and weeks. With iodine deficiency, this process is disrupted. Iodine entering the body in physiological quantities prevents the development of endemic goiter; normalizes the size of the thyroid gland in newborns, children, adolescents and adult patients; affects the indicators of the ratio T3 / T4, the level of TSH.

Pharmacokinetics. After oral administration, inorganic iodine is almost completely absorbed in the small intestine. Within 2 hours after absorption, iodine is distributed in the intercellular space; accumulates in the thyroid gland, kidneys, stomach, mammary and salivary glands. The volume of distribution in a healthy person averages 23 liters (38% of body weight). The concentration in blood plasma after the application of a standard dose is 10-50 ng / ml, while the iodine content in breast milk, saliva, gastric juice is 30 times higher than the concentration in blood plasma. The thyroid gland contains ¾ (10–20 mg) of all iodine in the body. Iodine is excreted mainly in urine, to a lesser extent in feces and exhaled air. When the equilibrium concentration is reached, the amount of removed iodine is proportional to the daily intake with food.

Prevention of the development of iodine deficiency, including during pregnancy or lactation.

Prevention of recurrence of iodine-deficient goiter after surgical treatment, as well as after the completion of complex treatment with thyroid hormone preparations.

Treatment of diffuse euthyroid iodine deficiency goiter in children, including newborns and infants, and young adults.

Prevention of iodine deficiency and endemic goiter in cases when the intake of iodine in the body of an adult is 150-200 mcg / day. it is necessary to additionally apply the following amount:

Prevention of recurrence of iodine deficiency goiter after surgical treatment, as well as after the completion of complex treatment with thyroid hormones: children and adults - 100-200 mcg of iodine per day (1-2 tablets Iodomarin 100 or ½ – 1 tablets Iodomarin 200).

Treatment of diffuse euthyroid iodine deficiency goiter:

newborns, infants and children: 100-200 mcg of iodine per day (1-2 tablets Iodomarin 100 or ½ – 1 tablets Iodomarin 200);

young adults: 300-500 micrograms of iodine per day (3-5 Iodomarin 100 tablets or 1½ – 2½ Iodomarin 200 tablets).

Mode of application. Take the tablets after meals and drink plenty of fluids, such as a glass of water. For infants and children under the age of 3 years, the preparation can be given in crushed form. The use of the preparation for prophylactic purposes is carried out, as a rule, for several months or years, and more often - for the whole life. For the treatment of goiter in newborns and infants, in most cases, 2–4 weeks are sufficient, in children and adults - 6–12 months or more. The question of the dosage and duration of use of the preparation for preventive measures or for the treatment of thyroid diseases is decided by the doctor on an individual basis.