Limenda 7 vaginal suppositories — Made in Turkey — Free Delivery

For local treatment of vaginal candidiasis, bacterial and Trichomonas vaginitis and vaginitis caused by mixed infections.

1 suppository should be injected deep into the vagina at night for 7 days.

In case of recurrence of the disease or vaginitis resistant to other treatment, Limenda should be used within 14 days.

Vaginal suppositories must be inserted deep into the vagina using a disposable fingertip, which is in the package.

For elderly patients (over 65 years of age), dosage adjustment is not required.

Hypersensitivity to any of the active ingredients of the preparation or to their derivatives, porphyria, epilepsy, severe liver dysfunction.

The frequency of systemic adverse reactions is negligible due to the very low level of metronidazole in blood plasma during vaginal administration of the preparation (2-12% compared with oral administration). miconazole nitrate can cause vaginal irritation (burning, itching), like all other antifungal agents containing imidazole derivatives used intravaginally (2-6%). these complaints quickly disappear with continued treatment. in case of severe irritation, treatment should be discontinued.

Adverse reactions registered with the systemic use of the active substances of the preparation are listed below.

On the part of the blood and lymphatic system: the frequency is unknown - leukopenia.

On the part of the blood and the immune system: the frequency is unknown - hypersensitivity reactions.

Mental disorders: infrequently - depression; rarely - mental disorders.

From the nervous system: rarely - ataxia, convulsions, dizziness, headache; the frequency is unknown - increased fatigue or weakness, peripheral neuropathy due to active and / or prolonged therapy with metronidazole.

From the digestive tract: the frequency is unknown - changes in taste, metallic taste, nausea, vomiting, constipation, dry mouth, diarrhea, lack of appetite, pain or cramps in the abdomen.

Violation of the general condition and condition at the injection site: very often - vaginal discharge; often - vaginitis, vulvovaginal irritation, discomfort of the pelvic organs; infrequently - a feeling of thirst; rarely - a feeling of heat in the vagina, itching, irritation, rash; frequency unknown - local irritation and hypersensitivity, contact dermatitis.

Side effects such as inflammation of the oral mucosa, stomatitis, glossitis, pancreatitis, hot flashes are also possible; rash, which may be accompanied by fever; urticaria, angioedema, anaphylactic shock, pustular rash; encephalopathy (e.g. confusion) and subacute cerebellar syndrome (e.g. ataxia, dysarthria, gait disturbance, nystagmus, tremor), which may resolve after discontinuation of the preparation, aseptic meningitis, psychotic disorders, confusion, hallucinations, diplopia, myopia, decreased visual acuity, changes in color perception, optic neuropathy/neuritis; agranulocytosis, neutropenia and thrombocytopenia, increased activity of liver enzymes (AsAT, AlAT, alkaline phosphatase), cholestatic or mixed hepatitis and hepatocellular liver damage, sometimes with jaundice; cases of liver failure requiring liver transplantation have been reported in patients treated with metronidazole and other antibiotics; increase in body temperature.

These side effects are rare, since the concentration of metronidazole in the blood is much lower with intravaginal administration.