Tritace Plus 5mg/12.5mg 28 tablets — Made in Italy — Free Delivery

Product description 

Compound

Contraindications

• hypersensitivity to the active substance ramipril or other ACE inhibitors (angiotensin-converting enzyme), hydrochlorothiazide, other thiazide diuretics, sulfonamides or any of the excipients that are part of the preparation;
• a history of angioedema (hereditary, idiopathic or previously transferred against the background of the use of ACE inhibitors or angiotensin II receptor antagonists);
• arterial hypotension or hemodynamically unstable conditions;
• simultaneous use with sacubitril / valsartan;
• the simultaneous use of ACE inhibitors and extracorporeal therapies that lead to blood contact with negatively charged surfaces (such use can lead to severe anaphylactic reactions); such extracorporeal therapies include dialysis or hemofiltration using certain high fluid permeability membranes (eg polyacrylonitrile) and low density lipoprotein apheresis using dextran sulfate;
• significant bilateral stenosis of the renal arteries or unilateral stenosis of the renal artery of a single kidney;
• severe renal dysfunction (creatinine clearance < 30 ml / minute) in patients who are not undergoing hemodialysis;
• clinically significant electrolyte imbalance, the course of which may worsen during treatment;
• treatment-resistant hypokalemia or hypercalcemia;
• refractory hyponatremia;
• symptomatic hyperuricemia (gout);
• anuria;
• severe liver dysfunction, hepatic encephalopathy;
• pregnancy and pregnancy planning;
• the period of breastfeeding;
• simultaneous use of the preparation "Tritace Plus® 5 mg / 12.5 mg" with preparations containing aliskiren in patients with diabetes mellitus or renal dysfunction (glomerular filtration rate (GFR) < 60 ml / minute / 1.73 m2);
• simultaneous use with angiotensin II receptor antagonists in patients with diabetic nephropathy.

Mode of application

Application features

Overdose