Vitaxon 60 tablets — Made in Ukraine — Free Delivery

Pharmacological properties

Pharmacodynamics. Neurotropic B vitamins have an effect on inflammatory and degenerative diseases of the nervous tissue and musculoskeletal system. They are used to eliminate deficiency conditions, and in high doses they exhibit analgesic properties, improve blood circulation, normalize the functioning of the nervous system and the process of hematopoiesis.

Pharmacokinetics. Vitamin B6 and its derivatives are mostly rapidly absorbed in the upper digestive tract by passive diffusion and excreted within 2-5 hours.

Indications

With neurological diseases caused by a proven deficiency of vitamins B1, B6.

Application

Take orally with plenty of liquid.

The recommended dose is 1 tablet per day. In individual cases, the dose should be increased and taken 1 tablet 3 times a day.

The tablets should be taken whole after meals.

The duration of the course of treatment is determined by the doctor individually in each case. After the maximum treatment period (4 weeks), a decision is made to correct and reduce the dose of the preparation.

Contraindications

Hypersensitivity to the components of the preparation.

The use of vitamin B1 is contraindicated in case of allergic reactions.

The use of vitamin B6 is contraindicated in case of stomach and duodenal ulcers in the acute stage (since the acidity of gastric juice may increase).

Side effects

From the digestive tract: nausea, vomiting, diarrhea, abdominal pain, increased acidity of gastric juice.

On the part of the cardiovascular system: tachycardia.

From the immune system: hypersensitivity reactions, including anaphylactic shock; anaphylaxis, urticaria.

On the part of the skin: skin rashes, itching.

In very rare cases: state of shock.

Long-term use (more than 6-12 months) at a dose of more than 50 mg of vitamin B6 daily can lead to peripheral sensory neuropathy, nervous excitement, dizziness, headache.

Special instructions

The question of using Vitaxone for the treatment of patients with severe and acute decompensated heart failure is decided by the doctor individually, taking into account the patient's condition.

Application during pregnancy or lactation. The daily requirement for vitamin B6 during pregnancy or lactation is up to 25 mg. The preparation contains 100 mg of vitamin B6, so it should not be used during this period.

Children. The efficacy and safety of the preparation in children have not been established, so it should not be prescribed to this age group of patients.

The ability to influence the reaction rate when driving or working with other mechanisms. Since in some patients, the preparation can cause side effects such as dizziness, headache and tachycardia, care should be taken when driving or operating other mechanisms.

Interactions

Pyridoxine is incompatible with preparations containing levodopa, since with simultaneous use, the peripheral decarboxylation of levodopa increases and thus its antiparkinsonian effect decreases.

Benfotiamine is incompatible with oxidizing and reducing compounds: mercury chloride, iodide, carbonate, acetate, tannic acid, iron-ammonium citrate, as well as sodium phenobarbital, riboflavin, benzylpenicillin, glucose and metabisulfite, since 5-fluorouracil is activated in their presence. Copper accelerates the breakdown of benfotiamine; in addition, thiamine loses its effect with increasing pH values ​​(3).

Antacids reduce the absorption of thiamine.

Loop diuretics (such as furosemide), which inhibit tubular reabsorption, during prolonged therapy can cause an increase in thiamine excretion and thus reduce thiamine levels.

Overdose

In case of an overdose, the symptoms of side effects of the preparation increase.

Treatment: gastric lavage, the use of activated carbon. Therapy is symptomatic.

Vitamin B1 in high doses has a curariform effect.

Long-term use (more than 6-12 months) in doses of 50 mg of vitamin B6 daily can lead to peripheral sensory neuropathy.

With prolonged use of vitamin B1 at a dose of 2 g / day, neuropathies with ataxia and sensitivity disorders, cerebral convulsions with changes in the EEG, and in some cases, hypochromic anemia and seborrheic dermatitis were recorded.

Storage conditions

In its original packaging at 2–8 ° C.