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Product description

Nurofen Express Forte Tabs contains ibuprofen as ibuprofen with lysine. Lysine increases the solubility of ibuprofen and thus enables its faster absorption. It takes approximately 35 minutes to start working after taking your tablet. Ibuprofen belongs to a group of non-steroidal anti-inflammatory preparations (NSAIDs) that have the ability to reduce symptoms such as pain, swelling and fever caused by inflammation.


The acute headache phase of migraine with or without aura.
Tension headache.
Pain conditions (e.g. back pain, toothache, muscle pain, joint pain, dysmenorrhea, neuralgia).
Pains in the course of colds and flu.


1 tablet contains:
  • 400 mg of ibuprofen as ibuprofen with lysine (684 mg)
  • in addition, the preparation contains the core components: povidone, sodium carboxymethyl starch Type A, magnesium stearate,
  • shell components: hypromellose, talc, Opaspray White M-1-7111B (hypromellose, titanium dioxide E 171),
  • ink components: Opacode S-1-277001 (shellac, black iron oxide (E 172), propylene glycol).


Ibuprofen belongs to a group of non-steroidal anti-inflammatory preparations (NSAIDs) that have the ability to reduce symptoms such as pain, swelling and fever caused by inflammation.


Always take this medicine exactly as described in this leaflet or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if you are not sure.
Adults and children over 12 years of age: initial dose 1 tablet, then, if necessary, 1 tablet every 4 hours. Do not exceed the dose of 3 tablets a day. There should be an interval of at least four hours between each dose.
Elderly patients: The elderly are at greater risk of side effects. They can be minimized by using the lowest effective dose for the shortest possible time.
Oral preparation. Swallow the tablets with a sufficient amount of liquid. The tablets should not be chewed. If, despite taking the preparation, fever and pain persist or worsen, contact your doctor. For adolescents 12-18 years of age, medical advice should be sought if treatment is required for more than 3 days or if symptoms worsen.


If you are allergic to ibuprofen or any of the other ingredients of this medicine.
If you have ever had hypersensitivity reactions (e.g. hives, rhinitis, angioedema or bronchial asthma) after taking acetylsalicylic acid or other non-steroidal anti-inflammatory preparations (NSAIDs).
If you have an active or a history of recurrent peptic ulcer or bleeding (two or more clear episodes of proven ulceration or bleeding).
With a history of gastrointestinal perforation or bleeding, related to previous NSAID therapy.
With severe liver failure, severe renal failure, or severe heart failure.
During the last trimester of pregnancy.
With a hemorrhagic diathesis.


Keep out of the sight and reach of children.
Store below 25 ° C.

Side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. The following side effects have been reported with the short-term use of ibuprofen in the treatment of mild to moderate fever and pain at over-the-counter doses. While using ibuprofen in other indications and long-term, other side effects may occur.
Side effects are ranked by frequency using the following terms:
·         Very common: more than 1 in 10 patients treated.
·         Common: less than 1 in 10 but more than 1 in 100 patients.
·         Uncommon: less than 1 in 100 but more than 1 in 1000 patients.
·         Rare: less than 1 in 1,000 but more than 1 in 10,000 patients.
·         Very rare: less than 1 in 10,000 patients.
·         Not known: cannot be estimated from the available data.
Not so often:
·         stomach ache, nausea and indigestion
·         headaches,
·         hypersensitivity with hives and itching,
·         various skin rashes.
·         diarrhea, gas, constipation, vomiting.
Very rarely:
·         hematopoietic system disorders,
·         severe hypersensitivity reactions including swelling of the face, tongue and throat, shortness of breath, tachycardia (increased heart rate), drop in blood pressure (sudden, severe allergic reaction, angioedema or severe shock)
·         aseptic meningitis,
·         peptic ulcers, perforation or bleeding, tarry stools, and bloody vomiting
·         mouth ulcers and gastritis
·         liver disorders
·         severe skin reactions such as blistering reactions including Stevens-Johnson syndrome, erythema multiforme and toxic epidermal necrolysis
·         acute kidney failure,
·         decrease in hemoglobin.
Not known:
·         heart failure and swelling
·         hypertension,
·         airway responsiveness including asthma, bronchospasm, shortness of breath
·         exacerbation of colitis and Cohn's disease,
·         kidney failure
·         heart failure and swelling
·         hypertension,
·         airway responsiveness including asthma, bronchospasm, shortness of breath
·         exacerbation of colitis and Crohn's disease,
·         kidney failure
Severe skin reactions known as DRESS syndrome may occur. Symptoms of DRESS include skin rash, fever, swollen glands, and an increase in eosinophils (a type of white blood cell).
In isolated cases, gastric ulcer and / or duodenal ulcer, gastrointestinal bleeding, sometimes fatal, especially in the elderly, and perforation may occur. In patients with pre-existing autoimmune diseases (systemic lupus erythematosus, mixed connective tissue disease), isolated cases of symptoms occurring in aseptic meningitis such as neck stiffness, headache, nausea, vomiting, fever and confusion have been reported during treatment with ibuprofen. Taking medicines such as Nurofen Express Forte Tabs may be associated with a slightly increased risk of heart attack (heart attack) or stroke. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.


The use of Nurofen concomitantly with acetylsalicylic acid should be avoided, unless the doctor has prescribed low doses (not more than 75 mg / day) and with other preparations from the group of non-steroidal anti-inflammatory preparations (NSAIDs), including selective cyclooxygenase-2 inhibitors. The concomitant use of two or more NSAIDs should be avoided because of a possible increased risk of side effects.
Tell your doctor about all the medicines you are taking, are taking, have recently taken or plan to take, and about medicines you can buy without prescription. Nurofen Express Forte Tabs may influence the effect of other medicines or other medicines may influence the way Nurofen Express Forte Tabs works.
·         Medicines with anticoagulant activity (i.e. blood thinning / preventing blood clots such as aspirin (acetylsalicylic acid), warfarin, ticlopidine)
·         medicines to lower blood pressure (ACE inhibitors such as captopril, beta blockers such as atenolol, angiotensin II receptor antagonists such as losartan)
·         antiplatelet preparations and selective serotonin reuptake inhibitors (SSRIs),
·         cardiac glycosides,
·         lithium and methotrexate,
·         cyclosporine
·         mifepristone,
·         tacrolimus,
·         zidovudine
·         quinolone antibiotics,
·         corticosteroids
·         probenecid or sulfinpyrazone,
·         antidiabetic preparations.

Warnings and Precautions

·         Talk to your doctor or pharmacist before taking Nurofen Express Forte Tabs if you have:
·         systemic lupus erythematosus and mixed connective tissue disease,
·         history of gastrointestinal diseases (ulcerative colitis, Crohn's disease),
·         high blood pressure and / or cardiac dysfunction,
·         kidney problems
·         liver dysfunction
·         blood coagulation disorders,
·         active or past bronchial asthma or symptoms of allergic reactions in the past,
·         bronchospasm may occur after taking the preparation,
·         diseases in which the patient is taking other preparations (especially anticoagulants, diuretics, cardiac preparations, corticosteroids).
The use of Nurofen concomitantly with NSAIDs, including selective cyclooxygenase-2 inhibitors, should be avoided. There is a risk of gastrointestinal haemorrhage, ulceration or perforation, which may be fatal and need not be preceded by warning symptoms; they can also occur in patients who develop warning symptoms. In the event of gastrointestinal haemorrhage or ulceration, treatment should be discontinued immediately. Patients with gastrointestinal diseases, especially the elderly, should report any unusual gastrointestinal symptoms (especially bleeding) to their doctor, especially at the beginning of treatment. Concomitant long-term use of different painkillers may lead to kidney damage with the risk of renal failure (postalgesic nephropathy). Taking anti-inflammatory and painkilling preparations such as ibuprofen may be associated with a slightly increased risk of a heart attack or stroke, especially when used in high doses. Do not exceed the recommended dose and duration of treatment.
Before using Nurofen Express Forte Tabs, discuss treatment with your doctor or pharmacist if:
·         you suffer from heart problems such as heart failure, angina (chest pain),
·         you have had a heart attack, bypass surgery, you have peripheral arterial disease (poor blood circulation in the legs due to narrowing or blockage of the arteries) or if you have had any stroke (including mini-stroke or transient ischemic attack (TIA))
·         you suffer from high blood pressure, diabetes, high cholesterol, a family history of heart disease or stroke, or if you smoke.
Rare severe skin reactions, some of them fatal, including exfoliative dermatitis, so called 'dermatitis', have been reported with the use of NSAIDs. Stevens-Johnson syndrome and toxic epidermal necrolysis. The greatest risk of these serious reactions is when starting treatment, in most cases during the first month of taking the medicine. The preparation should be discontinued at the first signs of skin rash, mucosal damage, or other signs of hypersensitivity.
Medicines of this class (Non-Steroidal Anti-Inflammatory preparations), may adversely affect female fertility. This effect is temporary and will disappear after the end of therapy. Talk to your doctor, even if the above warnings apply to situations in the past.
Children and youth
In dehydrated patients - adolescents 12-18 years of age, there is a risk of renal impairment.
Use of the preparation in elderly patients
Elderly people are more likely to experience side effects than younger people.
Pregnancy, breastfeeding and fertility
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Check with your doctor when using ibuprofen during the first 6 months of pregnancy. Ibuprofen is contraindicated in the last trimester of pregnancy due to the increased risk of complications for the mother and child during delivery.
Ibuprofen may pass into breast milk in small amounts. There are no known cases of undesirable effects in breastfed infants, therefore it is not necessary to stop feeding during short-term use of the preparation at the recommended doses.
Driving vehicles and operating machinery
Nurofen Express Forte Tabs has no influence on the ability to drive and use machines, if used as prescribed.


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