Affida Fort granules for oral suspension 100mg, 2p x 30 sachets — Made in Italy — Free Delivery

Product description

Granules for oral suspension Affida Fort are used in the treatment of acute pain, primary dysmenorrhea.

Structure

Active substance: nimesulide;

1 sachet of 2 g of granules contains 100 mg of nimesulide;

Excipients: cetomacrogol 1000, maltodextrin, citric acid, sucrose, orange flavor.

Contraindications

• hypersensitivity to nimesulide or to any excipient of this preparation;
• a history of hypersensitivity (eg, bronchospasm, rhinitis, urticaria, nasal polyps), including reactions to acetylsalicylic acid or other NSAIDs;
• a history of hepatotoxic reactions to taking nimesulide;
• concomitant use of other potentially hepatotoxic substances;
• alcoholism, preparation addiction;
• a history of gastrointestinal bleeding or perforation due to previous NSAID therapy;
• a history of active or recurrent peptic ulcer / bleeding (two or more distinct episodes of confirmed ulcerative lesion or bleeding);
• cerebrovascular bleeding or other active bleeding, or bleeding disorders;
• severe disorders of the blood coagulation system;
• severe heart failure;
• severe renal impairment;
• impaired liver function;
• patients with fever and / or flu-like symptoms;
• children under 12 years old;
• third trimester of pregnancy and lactation.

Mode of application

In order to minimize possible unwanted side effects, you need to use the lowest effective dose for a short time. Recommended to be consumed after meals.

The maximum duration of the course of treatment is 15 days.

Application features

Pregnant

Contraindicated.

Children

For use in children over 12 years of age.

Drivers

Carefully.

Overdose

Symptoms of acute NSAID overdose are usually limited to: apathy, drowsiness, nausea, vomiting, epigastric pain, which are usually reversible with maintenance therapy. Gastrointestinal bleeding is possible. In addition, arterial hypertension, acute renal failure, respiratory depression and coma may occur, but such phenomena are rare. There have been reports of anaphylactoid reactions when using therapeutic doses of NSAIDs, which may occur in case of overdose.

Side effects

The most common side effects are gastrointestinal reactions. Peptic ulcers, perforations, or gastrointestinal bleeding, sometimes fatal, may occur, especially in the elderly. After treatment, nausea, vomiting, diarrhea, flatulence, constipation, dyspepsia, abdominal pain, black stool, bloody vomiting, ulcerative stomatitis, exacerbation of colitis and Crohn's disease were also observed. Less commonly, gastritis was observed.

Interaction

In vitro studies have shown that nimesulide is displaced from the binding sites by tolbutamide, salicylic acid and valproic acid. Despite the fact that these interactions were determined in blood plasma, these effects were not observed during the clinical use of the preparation.

Storage conditions

Store at a temperature not exceeding 25 ° C out of reach of children.

Shelf life is 3 years.