Atorvastatin-Teva 20mg 30 tablets — Made in Spain — Free Delivery
(Atorvastatin-Teva)
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Description Atorvastatin-Teva 20mg 30 tablets — Made in Spain — Free Delivery
Product description
Atorvastatin-Teva tablets are indicated for:
- preventing cardiovascular disease;
- reducing the risk of myocardial infarction;
- reducing the risk of stroke;
- reducing the risk of revascularization procedures and angina pectoris.
- reducing the risk of non-fatal myocardial infarction;
- reducing the risk of fatal and non-fatal stroke;
- reducing the risk of hospitalization due to congestive heart failure.
Structure
Active substance: atorvastatin;
1 coated tablet contains 10 mg or 20 mg, 40 mg, or 80 mg of atorvastatin (in the form of atorvastatin calcium);
Excipients:
core: microcrystalline cellulose, sodium carbonate, maltose, sodium croscarmellose, magnesium stearate;
shell: hypromellose (E 464), hydroxypropyl cellulose, triethyl citrate (E 1505), polysorbate 80, titanium dioxide (E 171).
Contraindications
Hypersensitivity to any of the components of this medication.
Active liver disease, which may include a sustained increase in hepatic transaminase activity of unknown etiology.
During pregnancy and breastfeeding.
Women of childbearing age who do not use contraceptives.
Mode of application
Atorvastatin is intended for oral administration. The dose is taken in full 1 time per day every day, at any time of the day, regardless of food intake.
Before using atorvastatin, the patient should start a standard cholesterol-lowering diet and follow it in the future during treatment with atorvastatin.
The dose is selected individually in accordance with the baseline level of LDL cholesterol, the goal of therapy and the patient's response. The maximum dose is 80 mg once a day.
Application features
Pregnant
Contraindicated.
Children
From 10 years old.
Drivers
Has a very insignificant effect on the reaction rate when driving or working with other mechanisms.
Overdose
There is no specific treatment for atorvastatin overdose. In case of an overdose, the patient should be treated symptomatically and supportive measures should be taken if necessary. Due to the high degree of binding of the drug to plasma proteins, one should not expect a significant increase in the clearance of atorvastatin using hemodialysis.
Side effects
Adverse reactions reported in clinical and post-marketing studies include:
General disorders: malaise, pyrexia, asthenia, chest pain, peripheral edema, fatigue.
Interaction
The risk of developing myopathy during treatment with statins increases with the simultaneous use of fibric acid derivatives, lipid-modifying doses of niacin, cyclosporine, or potent inhibitors of CYP 3A4 (for example, clarithromycin, HIV protease inhibitors and itraconazole).
Grapefruit juice. Contains one or more components that inhibit CYP 3A4 and can increase plasma concentrations of atorvastatin, especially with excessive consumption of grapefruit juice (more than 1.2 liters per day).
Atorvastatin and its metabolites are substrates for the OATP1B1 transporter. OATP1B1 inhibitors (eg cyclosporin) can increase the bioavailability of atorvastatin. The AUC value of atorvastatin significantly increased with the simultaneous use of atorvastatin at a dose of 10 mg and cyclosporin at a dose of 5.2 mg / kg / day compared with the use of atorvastatin alone. The simultaneous use of atorvastatin and cyclosporine should be avoided.
Storage conditions
Keep out of the reach of children at a temperature not exceeding 30 ° C.
Shelf life is 2 years.
Tags: Atorvastatin
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