Betaderm ointment 2p x 15g — Made in Poland — Free Delivery
(Betaderm )
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Description Betaderm ointment 2p x 15g — Made in Poland — Free Delivery
Indications
Dermatoses that can be treated with corticosteroids in case of complication or suspected complication of a secondary infection caused by microorganisms sensitive to gentamicin: eczema (atopic, childhood, coin-like), anogenital and senile pruritus, contact dermatitis, seborrheic dermatitis, neurodermatitis, intertriginous dermatitis, solar dermatitis, exfoliative dermatitis, stasis dermatitis and psoriasis.
Application
Adults and children over the age of 12 years - the ointment is applied in a thin layer to the entire affected area of the skin 2 times a day - in the morning and in the evening.
The frequency of application of the preparation is determined individually depending on the severity of the disease. In mild cases, apply 1 time per day, with the most severe lesions, there may be a need for frequent use.
The duration of treatment depends on the size and location of the disease, as well as the patient's response to treatment. If clinical improvement is not observed within 3-4 weeks, the diagnosis should be reviewed by a physician.
Contraindications
The preparation is contraindicated in patients with hypersensitivity to corticosteroids, gentamicin or any other component of the preparation, as well as in case of skin tuberculosis, skin manifestations of syphilis, skin reactions after vaccination, widespread plaque psoriasis, varicose veins, perioral dermatitis, viral skin lesions, skin neoplasms, rosacea, acne vulgaris, chicken pox, other bacterial and fungal infections of the skin without proper antibacterial and antifungal therapy.
Do not use on large areas of affected skin, especially in cases of violation of the integrity of the skin, such as burns.
Side effects
Skin and subcutaneous tissue. very rarely: acne, steroid purpura, epidermal growth inhibition, subcutaneous tissue atrophy, folliculitis, erythema, hypertrichosis, secondary infection.
Very rare: urticaria or maculopapular rash, prickly heat, itching, burning sensation, irritation or exacerbation of existing changes.
Very rarely: dry skin, depigmentation or hyperpigmentation of the skin, skin discoloration, skin atrophy and stretch marks when using the preparation for more than the recommended period. Application on the face may cause perioral dermatitis.
Vascular system: very rarely: when using the preparation for longer than the recommended period, dilation of small blood vessels (telangiectasia) may occur.
Organ of hearing. Very rarely: use on mucous membranes or on large areas of skin, especially damaged, or under an occlusive dressing, may cause ototoxic effects due to the presence of gentamicin sulfate in the ointment and cream.
Endocrine system. Very rare: symptoms of hypercortisolism. Prolonged use of the ointment on large areas of the skin or under an occlusive dressing, or in children, given the increased absorption of betamethasone dipropionate, can cause a strong systemic effect characteristic of corticosteroids, which manifests itself in the form of edema, hypertension, decreased immunity, inhibition of growth and development in children, hyperglycemia, glucosuria, development of Cushing's syndrome.
Organ of vision. Individual cases: when applied topically to the skin of the eyelids, the preparation can sometimes cause the development of glaucoma or cataracts.
The immune system. Rarely: hypersensitivity to corticosteroids may occur, in which case the preparation should be discontinued immediately.
Renal and urinary tract disorders. Rare: use on large areas of skin, especially damaged, or under an occlusive dressing, may cause nephrotoxicity due to the presence of gentamicin sulfate in the ointment.
The preparation contains cetostearyl alcohol, which may cause a local skin reaction (eg contact dermatitis).
The preparation contains butylated hydroxytoluene and butylated hydroxyanisole, which may cause local skin reactions (eg contact dermatitis) or irritation of the eyes and mucous membranes.
special instructions
Do not use without interruption for more than 2 weeks.
With prolonged use of the preparation on large areas of the skin, the incidence of side effects and the possibility of developing bacterial resistance to gentamicin sulfate increase.
Cross-allergic reactions with antibiotics of the aminoglycoside group were noted.
If an infection develops at the site of application of the ointment, appropriate antibacterial or antifungal therapy should be carried out. If the symptoms of the infection do not disappear, it is necessary to stop using the preparation for the period of treatment of the infection.
Do not use the preparation on the skin of the face because of the risk of side effects (telangiectasia, perioral dermatitis) even after a short use.
It is necessary to use the preparation with caution in patients with psoriasis, since topical application of GCS in areas affected by psoriasis can lead to the spread of relapse caused by the development of tolerance, the risk of generalized pustular psoriasis and systemic toxicity caused by a decrease in the protective function of the skin.
On the skin in the groin area, apply only in case of special need, since increased absorption and a high risk of side effects (telangiectasia, perioral dermatitis) are possible, even after short-term use.
Use with caution if there are already existing atrophic changes in the subcutaneous tissue, especially in the elderly.
Do not apply ointment under an occlusive dressing, as this can cause atrophy of the epidermis, the occurrence of striae and secondary infection.
Systemic absorption of gentamicin when applied topically may increase when treating large areas of the skin, especially with prolonged use or in the presence of skin lesions. In such cases, appropriate preventive measures are recommended, especially in the treatment of children.
Prolonged topical use of antibiotics can sometimes lead to the growth of resistant microflora, including fungi. In this case, as well as with the development of irritation, sensitization or superinfection, the use must be discontinued and appropriate therapy instituted.
Use during pregnancy and lactation
Pregnancy. Betamethasone dipropionate is contraindicated during pregnancy.
Lactation. It is not known whether betamethasone dipropionate passes into breast milk after topical application, so it is not recommended for use during breastfeeding.
Children. The preparation is not used in children under the age of 12 years. The use of the preparation is possible only if the expected benefit outweighs the potential risk of adverse reactions. In the case of use in children, it is necessary to take into account the possibility of signs of depression of the hypothalamic-pituitary-adrenal system, which occur in children more often than in adult patients, which is associated with greater absorption of the preparation in children due to a larger ratio of skin area to body weight.
In children who received topical corticosteroids, adrenal suppression, Cushing's syndrome, growth retardation, underweight, increased intracranial pressure were noted.
Manifestations of suppression of the function of the adrenal cortex: a low level of cortisol in the blood plasma and a lack of response to the test for stimulation of the adrenal glands using ACTH preparations. An increase in intracranial pressure is manifested by protrusion of the crown of the head, headache, bilateral edema of the optic nerve head.
The ability to influence the reaction rate when driving vehicles or working with other mechanisms. The preparation does not affect mental and motor activity, as well as the ability to drive vehicles and work with mechanisms.
Interactions
Interactions with local application of corticosteroids have not been identified. however, it should be noted that during treatment with the preparation it is not recommended to vaccinate against smallpox, as well as to carry out other types of immunization (especially with prolonged use on large areas of the skin) due to the possible lack of an adequate immunological response.
The preparation can enhance the effect of immunosuppressive and reduce the severity of the action of immunostimulating preparations.
Overdose
With prolonged use on large areas of the skin, at high doses, with the use of an occlusive dressing, overdose symptoms may occur, which are manifested by an increase in systemic side effects characteristic of corticosteroids (hyperglycemia, glucosuria, Cushing's syndrome).
A single overdose of gentamicin did not result in overdose symptoms. Excessive or prolonged use of gentamicin may lead to overgrowth of antibiotic-insensitive microorganisms.
Treatment. Assign appropriate symptomatic therapy. The symptoms of acute hypercortisolism are usually reversible. If necessary, carry out a correction of the electrolyte balance. In the case of chronic toxic effects, the gradual abolition of GCS is recommended. In case of excessive growth of resistant microorganisms, it is recommended to stop treatment with the preparation and prescribe the necessary therapy.
Storage conditions
At a temperature not higher than 25 °C. do not freeze.
Tags: Betaderm
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