Betaklav (Amoxicillin) 500mg/125mg 14 tablets — Made in Slovenia by KRKA — Free Delivery

Product description

Betaclav tablets are used to treat bacterial infections caused by microorganisms sensitive to the preparation:

• acute bacterial sinusitis;
• acute otitis media;
• confirmed exacerbation of chronic bronchitis;
• community-acquired pneumonia;
• cystitis;
• pyelonephritis;
• infections of the skin and soft tissues, including cellulite, animal bites, severe dentoalveolar abscesses with widespread cellulite;
• infections of bones and joints, including osteomyelitis.

Composition

Active ingredients: amoxicillin, clavulanic acid;

1 tablet contains 500 mg of amoxicillin in the form of amoxicillin trihydrate and 125 mg of clavulanic acid in the form of potassium clavulanate or 875 mg of amoxicillin in the form of amoxicillin trihydrate and 125 mg of clavulanic acid in the form of potassium clavulanate;

Excipients: microcrystalline cellulose, magnesium stearate, sodium starch (type A), colloidal silicon dioxide, Opadry White Y-1-7000 (contains hypromellose, macrogol 400 and titanium dioxide (E 171)).

Contraindications

• hypersensitivity to the components of the preparation, to any antibacterial agents of the penicillin group;
• a history of severe hypersensitivity reactions (including anaphylaxis) associated with the use of other beta-lactam agents (including cephalosporins, carbapenems, or monobactams);
• a history of jaundice or liver dysfunction associated with the use of amoxicillin / clavulanate.

Mode of application

The preparation should be used according to official antibiotic recommendations and local antibiotic susceptibility data. Sensitivity to amoxicillin / clavulanate differs from region to region and may change over time. If necessary, refer to the local sensitivity data and, if necessary, carry out a microbiological determination and a sensitivity test.

Since the tablet cannot be divided, this dosage form should not be prescribed for children weighing less than 25 kg.

Application features

Pregnant

As with other medicines, the use of the preparation should be avoided during pregnancy, especially in the first trimester, unless the benefits of using the preparation outweigh the potential risk.

Children

Use for children aged 6 years and over with a body weight of at least 25 kg.

Drivers

Studies to study the ability of the preparation to influence the reaction rate when driving vehicles or other mechanisms have not been carried out. However, side reactions (eg allergic reactions, dizziness, convulsions) may occur, which may affect the ability to drive a car or other mechanisms.

Overdose

Overdose may be accompanied by symptoms from the gastrointestinal tract and an imbalance in water and electrolyte balance. These phenomena are treated symptomatically, paying attention to the correction of water-electrolyte balance. Cases of crystalluria have been reported, which can sometimes cause renal failure. Betaclav can be removed from the blood by hemodialysis.

Side effects

Infections and invasions: candidiasis of the skin and mucous membranes, excessive increase in insensitive microorganisms, aseptic meningitis.

From the circulatory and lymphatic systems: reversible leukopenia (including neutropenia), thrombocytopenia, reversible agranulocytosis, hemolytic anemia, increased bleeding time and prothrombin index.

From the immune system: angioedema, anaphylaxis, serum-like syndrome, allergic vasculitis.

From the nervous system: dizziness, headache, circulatory hyperactivity and convulsions.

From the digestive tract: diarrhea, nausea, vomiting, indigestion, antibiotic-associated colitis (including pseudomembranous and hemorrhagic colitis), black hairy tongue.

On the part of the hepatobiliary system: a moderate increase in the level of AST and / or ALT was observed in patients who were treated with antibiotics of the beta-lactam group, but the clinical significance of this has not been established; hepatitis, cholestatic jaundice. These phenomena have occurred with the use of other penicillins and cephalosporins.

Skin and subcutaneous tissue disorders: skin rashes, itching, urticaria, erythema polymorphism, Stevens-Johnson syndrome, toxic epidermal necrolysis, bullous exfoliative dermatitis, acute generalized exanthematous pustulosis.

On the part of the kidneys and urinary system: interstitial nephritis, crystalluria.

Interaction

The simultaneous use of probenecid is not recommended. Probenecid reduces the renal tubular secretion of amoxicillin. The simultaneous use of probenecid can lead to an increase in the level and duration of action of amoxicillin (but not clavulanic acid) in the blood.

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C.

Shelf life is 2 years.