Biseptol oral suspension 200mg/40mg/5ml, 80ml — Made in Poland — Free Delivery
(Biseptol )
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Description Biseptol oral suspension 200mg/40mg/5ml, 80ml — Made in Poland — Free Delivery
Product description
Oral suspension "Biseptol" is used for infections caused by microorganisms sensitive to cotrimoxazole:
- infections of the upper and lower respiratory tract and ear infections: exacerbation of chronic bronchitis, bronchiectasis, pneumonia (including pneumonia caused by Pneumocystis jiroveci), sinusitis, otitis media;
- infections of the genitourinary system: acute and chronic cystitis, pyelonephritis, urethritis, prostatitis;
- infections of the digestive tract, including typhoid and paratyphoid fever (including treatment of chronic carriers) and cholera (in addition to fluid and electrolyte recovery);
- other bacterial infections caused by susceptible microorganisms: acute brucellosis, nocardiosis, actinomycetoma (except caused by real fungi), American blastomycosis (Paracoccidioides brasiliensis).
In osteomyelitis - as a last-line preparation (for example, if vancomycin is contraindicated), if the sensitivity of multi-resistant pathogens to cotrimoxazole has been proven.
Official guidelines for the appropriate use of antibiotics should be followed, especially those for use to prevent an increase in antibiotic resistance.
Compound
5 ml of suspension contains (active ingredients):
sulfamethoxazole - 200 mg;
trimethoprim - 40 mg.
Excipients: polyethylene glycol (macrogol) hydroxystearate, sodium carmellose, aluminum magnesium silicate, citric acid monohydrate, sodium hydrogen phosphate dodecahydrate, methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216), liquid maltitol, aromatics, aromatic sodium, aromatic sodium, ), propylene glycol, purified water.
Contraindications
- hypersensitivity to active substances, to sulfonamides or trimethoprim or to any of the excipients;
- severe parenchymal liver disease;
- severe impairment of renal function (creatinine clearance <15 ml / minute), if it is not possible to periodically determine the concentration of trimethoprim and sulfamethoxazole in blood plasma;
- megaloblastic anemia due to folate deficiency;
- immune thrombocytopenia caused by the use of trimethoprim and / or sulfonamides;
- hematological disorders;
- combination with dofetilide;
- deficiency of glucose-6-phosphate dehydrogenase;
- should not be used in children under 2 months of age;
- porphyria;
- the last trimester of pregnancy and breastfeeding.
Mode of application
Biseptol should be taken every 12 hours. The preparation is best used after meals with sufficient liquid. In acute infections, "Biseptol" is prescribed for a period of at least 5 days.
The preparation is administered orally.
Shake before use until a homogeneous suspension is obtained.
A graduated measure is attached to the bottle.
Children and adolescents:
2-5 months - 2.5 ml (morning and evening) with an interval of 12 hours;
6 months - 5 years - 5 ml twice a day with an interval of 12 hours;
6-12 years old - 10 ml twice a day with an interval of 12 hours;
12 years - 20 ml twice a day with an interval of 12 hours.
The dosage regimen corresponds approximately to the daily dose of 6 mg of trimethoprim and 30 mg of sulfamethoxazole per 1 kg of body weight. For severe infections, the dose can be increased by 50%.
Adults: take 20 ml of suspension every 12 hours. The minimum dose for adults and adolescents over 12 years of age, as well as for long-term treatment (longer than 14 days) - 10 ml of suspension every 12 hours. In especially difficult cases of infection - 30 ml of suspension every 12 hours.
Application features
Pregnant
Trimethoprim and sulfamethoxazole cross the placental barrier; their safety in pregnant women has not been established. It is not recommended to prescribe the preparation during pregnancy, especially in the first trimester, unless the expected benefit to the mother outweighs the risk to the fetus.
Children
The preparation can be used in children from 2 months. "Biseptol" should not be prescribed to premature babies, as well as newborns during the first 2 months of life, given the increased risk of kernicterus (bilirubin encephalopathy).
Drivers
"Biseptol" usually does not directly affect the ability to drive vehicles or work with other mechanisms. However, there is a possibility of side effects from the nervous system and psyche that can affect this ability, in some cases - to a large extent.
Overdose
Symptoms of acute overdose: nausea, vomiting, diarrhea, colic, headache, vertigo, dizziness, drowsiness, loss of consciousness, confusion, fever, intellectual and visual disturbances, jaundice, changes in blood composition, in severe cases - crystalluria, hematuria and anuria.
Symptoms of chronic overdose: inhibition of hematopoiesis (thrombocytopenia, leukopenia, megaloblastic anemia), as well as other pathological changes in the blood picture due to folic acid deficiency.
Treatment (depending on symptoms): gastric lavage, taking medications that induce vomiting, increased renal excretion by forced diuresis (alkalinization of urine promotes the elimination of sulfamethoxazole), hemodialysis (peritoneal dialysis is ineffective). It is necessary to monitor the blood picture and the level of electrolytes. With pronounced pathological changes in the blood picture or jaundice, specific treatment is prescribed. To eliminate the effect of trimethoprim on hematopoiesis, calcium folinate can be prescribed at a dose of 3-6 mg for 5-7 days.
Side effects
The main side effects are skin reactions and mild gastrointestinal disturbances, observed with treatment in about 5% of cases.
Storage conditions
Store in its original packaging at a temperature not exceeding 25 ° C, out of the reach of children.
After opening, store the bottle with a tightly closed cap for 8 months.
Shelf life is 3 years.
Tags: Biseptol
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