Coldrex Menthol Active powder for oral solution 10 sachets — Made in Spain — Free Delivery
(Coldrex Menthol Active)
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Description Coldrex Menthol Active powder for oral solution 10 sachets — Made in Spain — Free Delivery
Product description
Coldrex Menthol Active powder for oral solution is indicated for the relief of symptoms of colds and flu, including headache, sore throat, body aches and pains, nasal congestion, sinusitis and associated pain, acute catarrhal rhinitis, and fever.
Composition
Active ingredients: paracetamol, phenylephrine hydrochloride, ascorbic acid;
1 sachet contains paracetamol 600 mg, ascorbic acid 40 mg, phenylephrine hydrochloride 10 mg
Excipients: sucrose, sodium, citric acid, corn starch, menthol powder E41580, lemon flavor 610399E, honey flavor PFWIS PHS-050860, honey flavor F7624 / P, simple caramel 626E150A, aspartame (E 951), sodium saccharin.
Contraindications
Hypersensitivity to the components of the preparation. Simultaneous use of other sympathomimetic decongestants (even local action). Severe violations of liver and / or kidney function, severe forms of diabetes mellitus, prostatic hypertrophy with urinary retention, hyperthyroidism, severe diseases of the cardiovascular system, severe arterial hypertension.
Pheochromocytoma, glucose-6-phosphate dehydrogenase deficiency, blood diseases (including severe anemia, leukopenia), acute pancreatitis, epilepsy, glaucoma. Do not use simultaneously and within 2 weeks after using MAO inhibitors, together with tricyclic antidepressants, beta-blockers, and other antihypertensive preparations.
Do not use in patients with phenylketonuria due to the presence of aspartame (E 951).
Mode of application
The preparation is taken orally. Pour the contents of one sachet into a 200 - 300 ml cup and fill up to half a cup with hot water (not boiling water). Stir until completely dissolved. Add cold water if necessary. Take warm.
Adults and children over 12 years old: 1 sachet every 4 to 6 hours, if necessary. Do not take more than 4 hours later. The maximum daily dose is 6 sachets. The maximum duration of treatment without consulting a doctor is 7 days.
Exceed the indicated doses. If symptoms persist, you should see a doctor.
The lowest effective dose should be used.
Application features
Pregnant
Do not use during pregnancy and lactation.
Children
Do not use in children under 12 years of age.
Drivers
In the event of side effects such as dizziness, it is recommended to avoid driving and operating machinery.
Overdose
Paracetamol. The risk of overdose is increased in patients with liver disease and in those who abuse alcohol. Paracetamol overdose can cause liver failure, may necessitate liver transplantation, or lead to death.
Liver damage is possible in adults who have taken more than 10 g of paracetamol, and in children who have taken more than 150 mg / kg of body weight. The use of 5 g or more of paracetamol can lead to liver damage in patients with risk factors (long-term treatment with carbamazepine, phenobarbital, phenytoin, primidone, rifampicin, St. John's wort or other preparations that induce liver enzymes; regular intake of excessive amounts of ethanol; glutathione cachexia (digestive disorders , cystic fibrosis, HIV infection, hunger, cachexia).
Side effects
From the blood and lymphatic system: anemia (including hemolytic), sulfhemoglobinemia and methemoglobinemia, thrombocytopenia, leukopenia, agranulocytosis, bruising or bleeding.
From the immune system: anaphylaxis, allergic skin reactions (including rash, angioedema, Stevens-Johnson syndrome / toxic epidermal necrolysis),
hypersensitivity reactions.
From the respiratory system, chest and mediastinal organs: bronchospasm in patients sensitive to aspirin and other NSAIDs.
Hepatobiliary system: impaired liver function, increased activity of hepatic enzymes, hepatonecrosis (dose-dependent effect), liver failure.
Mental disorders: anxiety, nervous agitation, irritability, sleep disturbance.
Neurological disorders: headache, dizziness, insomnia.
On the part of the hearing organs and vestibular apparatus: tinnitus.
Gastrointestinal disorders: nausea, vomiting, dry mouth, hypersalivation, abdominal discomfort and pain, loss of appetite, heartburn, diarrhea.
Visual impairment: mydriasis, increased intraocular pressure, acute attack of glaucoma in patients with angle-closure glaucoma.
From the side of the cardiovascular system: increased blood pressure, tachycardia or reflex bradycardia, palpitations, shortness of breath.
On the part of the skin and subcutaneous tissue: allergic skin reactions (for example, rash, urticaria, allergic dermatitis). Cross-hypersensitivity reactions with other sympathomimetics are possible.
On the part of the kidneys and urinary system: impaired urination, urinary retention (more often in patients with prostatic hypertrophy), renal colic, nephrotoxic effect.
Interaction
The rate of absorption of paracetamol may increase with simultaneous use with metoclopramide and domperidone and decrease with cholestyramine. The anticoagulant effect of warfarin and other coumarins may increase with an increased risk of bleeding with simultaneous long-term regular daily use of paracetamol. With short-term use in accordance with the recommended regimen, these interactions have no clinical significance. Anticonvulsants (including phenytoin, barbiturates, carbamazepine), which stimulate the activity of microsomal liver enzymes, can increase the toxic effect of paracetamol on the liver due to an increase in the conversion of the preparation to hepatotoxic metabolites. The simultaneous use of high doses of paracetamol with isoniazid increases the risk of developing hepatotoxic syndrome. Do not use concomitantly with alcohol.
Storage conditions
Store at a temperature not exceeding 30 ° C out of the reach of children.
Shelf life is 2 years.
Tags: Coldrex
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