Coraxan 7.5mg 56 tablets — Made in Ireland — Free Delivery

Name: Coraxan 7.5mg 56 tablets — Made in Ireland — Free Delivery
Brand: Servier
SKU: Coraxan 7.5mg
Price: 28.81 USD
Availability: InStock

(Coraxan 7.5mg )

Availability: In Stock

Brand: Servier

View all products

View more in Preparations supporting the work of the heart

Free Shipping! If your country is on the checkout list, we deliver to you.

View list of countries

Delivery Timeframes:

Europe: 7 to 18 business days
US and the Rest of the World: 9 to 20 business days

Description
Reviews (0)

Description Coraxan 7.5mg 56 tablets — Made in Ireland — Free Delivery

Pharmachologic effect

Antianginal preparation. The mechanism of action consists in selective and specific inhibition of the If channels of the sinus node, which control spontaneous diastolic depolarization in the sinus node and regulate heart rate.

The main pharmacological feature of ivabradine is its ability to dose-dependently reduce heart rate. The analysis of the dependence of the magnitude of the decrease in heart rate on the dose of the preparation was carried out with a gradual increase in the dose of ivabradine to 20 mg 2 times / day. and revealed a tendency to achieve a plateau effect (no increase in the therapeutic effect), which reduces the risk of developing severe, poorly tolerated bradycardia (heart rate less than 40 beats / min).

When the preparation is prescribed in recommended doses, the decrease in heart rate is approximately 10 beats / min at rest and during exercise. As a result, the work of the heart decreases and the demand for oxygen in the myocardium decreases.

A sustained decrease in heart rate was demonstrated in patients taking ivabradine for at least 1 year (n = 713). No effect on glucose or lipid metabolism was observed.

In patients with diabetes mellitus (n = 457), ivabradine demonstrates efficacy and safety, as in other, comparable in number, patient groups.

Indications

Stable angina: symptomatic therapy of stable angina in IHD in adult patients with normal sinus rhythm and heart rate of at least 70 beats / min:

with intolerance or contraindications to the use of beta-blockers;

in combination with beta-blockers with inadequate control of stable angina pectoris against the background of the optimal dose of beta-blocker.

Chronic heart failure:

therapy of chronic heart failure II-IV class according to NYHA classification with systolic dysfunction in patients with sinus rhythm and heart rate of at least 70 bpm in combination with standard therapy, including therapy with beta-blockers, or in case of intolerance or contraindications to use beta-blockers.

Method of administration and dosage

Coraxan should be taken orally 2 times / day, in the morning and in the evening during meals. The dosage and duration of admission is determined by the doctor.

Contraindications

Resting heart rate below 60 beats / min (before treatment);

cardiogenic shock;
acute myocardial infarction;
severe arterial hypotension (systolic blood pressure below 90 mm Hg and diastolic blood pressure below 50 mm Hg);
severe liver failure (more than 9 points on the Child-Pugh scale);
SSSU;
sinoatrial blockade;
chronic heart failure of the III and IV functional class according to the NYHA classification (due to the lack of sufficient clinical data);
the presence of an artificial pacemaker;
unstable angina;
AV block III degree;
simultaneous use with strong inhibitors of CYP3A4, such as antifungal agents of the azole group (ketoconazole, itraconazole), antibiotics from the macrolide group (clarithromycin, oral erythromycin, josamycin, telithromycin), HIV protease inhibitors (nelfinavir, ritonavir) and nefazodonavir; and nefinavir;
hypersensitivity to ivabradine or any component of the preparation.

Special instructions

Coraxan is not effective for the treatment or prevention of cardiac arrhythmias. Its effectiveness decreases against the background of the development of tachyarrhythmias (for example, ventricular or supraventricular tachycardia).

The use of Coraxan in conjunction with calcium channel blockers that slow down the heart rate (verapamil or diltiazem) is not recommended.

The preparation contains lactose, therefore, Coraxan is not recommended for patients with lactose intolerance, lactase deficiency or impaired absorption of glucose and galactose.

With the use of grapefruit juice against the background of the use of Coraxan, an increase in the concentration of ivabradine in the blood was noted by 2 times. During the period of ivabradine therapy, the intake of grapefruit juice and St. John's wort preparations should be minimized.

It has been shown that, in general, the use of Coraxan does not affect the ability to drive, but due to the possibility of photopsy, the patient should be careful when engaging in potentially hazardous activities that require a high speed of psychomotor reactions.

Storage conditions

The preparation should be kept out of the reach of children. No special storage conditions are required.

Tags: Coraxan

Products viewed

Bulardi Max 10 sachets — Made in Poland — Free Delivery

Product descriptionBulardi ® Max is a symbiotic with antidiarrheal, antimicrobial, antitoxic and immunomodulatory properties.Features of theSaccharomyces Bulardi helps to prevent and eliminate the symptoms of acute diarrhea, intoxication and normalize the consistency of feces, create favo..

$21.88

Cardura 2mg 30 tablets — Made in Germany — Free Delivery

Indications.Arterial hypertension.The preparation is indicated for the treatment of arterial hypertension and for most patients it can be used to control blood pressure as monotherapy. In case of ineffectiveness of monotherapy for the treatment of arterial hypertension, the preparation can be used i..

$38.05

DiaB12, 30 capsules — Made in Poland — Free Delivery

Product descriptionLong-term treatment with metformin may lead to a progressive decline in the amount of vitamin B12 and folic acid in the body. Vitamin B12 helps in the proper functioning of the nervous system and, together with folates, in maintaining proper psychological functions that condition ..

$19.57

Dalacin vaginal suppositories 3 pcs with applicator — Made in USA — Free Delivery

Product descriptionClindamycin is a lincosamide antibiotic that inhibits bacterial protein synthesis by acting on bacterial ribosomes. The antibiotic binds predominantly to the 50S ribosomal subunit and affects the translation process. Although clindamycin phosphate is inactive in vitro, in vivo it ..

$46.34

Super D Plus, oral drops 10 ml — Made in Poland — Free Delivery

Product descriptionDietary supplement Super D Plus is recommended as a supplement to the diet as a source of vitamin D3.Active ingredientsTogether, vitamins D + E have an antioxidant effect, protect the child from the negative effects of oxidation products - together it is easier to protect the chil..

$21.42

Buyers Online

Customer from Brooklyn updated their account details
Customer from Brooklyn logged in
Customer from Strongsville logged in
Customer from Brooklyn updated their account details
Customer from Brooklyn placed a new order for VOLTAREN MAX GEL 180G - MADE IN SWITZERLAND - FREE SHIPPING
Customer from Brooklyn logged in
Customer placed a new order for DEBUTIR FORTE 60 СAPS — MADE IN POLAND- FREE SHIPPING
Customer from Ottawa updated their account details
Customer from Ottawa registered for an account
Customer placed a new order for STRESAM 50MG 60 PILLS - MADE IN FRANCE - FREE SHIPPING
Customer placed a new order for ACNE-DERM Cream 2p x 20Gr — Made in Poland by Uniapharm — Free Delivery
Customer placed a new order for Ascorbic acid 0,05g 2p x 160 tablets — Made in Ukraine — Free Delivery
Customer placed a new order for Fanigan 100 tablets — Made in India — Free Delivery
Customer from Raleigh placed a new order for Essentiale Forte 300 mg, 2p x 50 capsules — Made in Poland — Free Delivery
Customer from Raleigh logged in
Customer placed a new order for TENOTEN FOR CHILDREN 40 PILLS — MADE IN LITHUANIA — FREE SHIPPING
Customer from Raleigh logged in
Customer placed a new order for Aqua Maris for Children from Birth nasal drops 10 ml — Made in Croatia — Free Deliver
Customer from Raleigh logged in
Customer from Raleigh placed a new order for Essentiale Forte 300 mg, 2p x 50 capsules — Made in Poland — Free Delivery