Darilia 3mg/0.02mg, 84 tablets — Made in Hungary — Free Delivery
(Darilia )
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Description Darilia 3mg/0.02mg, 84 tablets — Made in Hungary — Free Delivery
Product description
Darilia tablets are indicated for oral contraception.
Compound
Active ingredients: drospirenone, ethinyl estradiol;
1 active tablet contains 3 mg crystalline drospirenone 100% and 0.02 mg micronized ethinyl estradiol 100%;
Excipients: lactose, corn starch, corn starch, macrogol and polyvinyl alcohol copolymer, magnesium stearate;
Film shell: polyvinyl alcohol, titanium dioxide (E 171), macrogol, talc, lecithin (soy)
1 placebo tablet contains;
Active ingredients: absent;
Excipients: microcrystalline cellulose, lactose, corn starch, magnesium stearate, colloidal silicon dioxide;
Film coat: polyvinyl alcohol, titanium dioxide (E 171), polyethylene glycol (macrogol), talc, indigotine (E 132), quinoline yellow (E 104), iron oxide black (E 172), sunset yellow FCF (E 110).
Contraindications
- Combined hormonal contraceptives (CHCs) should not be used if any of the following conditions are present. If any of these conditions occur for the first time during the use of CHC, the preparation should be stopped immediately.
- the presence or risk of developing venous thromboembolism (VTE);
- the presence or risk of developing arterial thromboembolism (ATE);
- diabetes mellitus with vascular complications;
- severe arterial hypertension;
- severe dyslipoproteinemia;
- the presence of severe liver disease at present or in history, until the indicators of liver function have returned to the normal range;
- severe renal failure or acute renal failure;
- the presence of liver tumors at present or in history (benign or malignant);
- or suspected malignant tumors (eg, genital or mammary glands) dependent on sex hormones;
- vaginal bleeding of unknown etiology;
- hypersensitivity to the active substances or to any of the components of the preparation;
Mode of application
Tablets should be taken every day at about the same time, if necessary, with a small amount of liquid, in the sequence indicated on the blister pack. There should be no breaks between taking the pills. It is necessary to take 1 tablet per day for 28 days in a row. Taking tablets from each subsequent package should be started after taking the last tablet from the previous package. Menstrual-like bleeding usually occurs on the 2-3rd day after the start of the placebo pills (green pills in the last row) and does not necessarily end before the start of the pills from the new package.
Application features
pregnant
Contraindicated.
Children
The preparation is indicated for use as prescribed by a doctor only after the onset of stable menstruation.
Overdose
So far, there are no data from clinical studies regarding an overdose of Darilia tablets. Based on general experience with combined oral contraceptives, overdose may cause nausea, vomiting, or, in young girls, vaginal bleeding. There is no specific antidote; treatment should be symptomatic.
Side effects
Mental disorders. emotional lability.
Nervous system. Headache.
From the gastrointestinal tract. Nausea.
From the reproductive system and mammary glands. Soreness of the mammary glands, metrorrhagia, amenorrhea.
Interaction
COCs may interfere with the metabolism of certain active substances. Accordingly, plasma and tissue concentrations may either increase (eg, cyclosporine) or decrease (eg, lamotrigine).
Based on in vivo interaction studies in female volunteers taking omeprazole, simvastatin and midazolam as substrate markers, it was found that a clinically significant interaction of drospirenone at a dose of 3 mg with other preparations that are induced by cytochrome P450 is unlikely.
Clinical data suggest that ethinylestradiol inhibits the clearance of CYP1A2 substrates, which in turn causes a slight (eg, theophylline) or moderate (eg, tizanidine) increase in their plasma concentrations.
Storage conditions
Store below 25°C in original packaging.
Keep out of the reach of children.
Shelf life - 2 years.
Tags: Darilia
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