Dermabin oinment 15g (Salicylic acid) — Made in Ukraine — Free Delivery

(Dermabin oinment )
Dermabin oinment 15g (Salicylic acid) — Made in Ukraine — Free Delivery
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Biopharma Brand: Biopharma
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Description Dermabin oinment 15g (Salicylic acid) — Made in Ukraine — Free Delivery

Pharmacological properties.

Betamethasone dipropionate is a synthetic fluorinated corticosteroid that has anti-inflammatory, antipruritic and vasoconstrictor effects. When applied topically, salicylic acid has a keratolytic effect.

Pharmacokinetics.

Absorption of betamethasone dipropionate by the body is possible mainly after prolonged use on a large surface of the skin.
Clinical characteristics.

Indications.

For local treatment of dermatoses sensitive to corticosteroids, such as chronic, erythematous or hyperkeratosis psoriasis and other dermatoses of an erythematous-squamous nature, in particular, seborrheic dermatitis (eczema), dry eczema in the desquamative phase, lichenification.

Contraindications

The preparation is contraindicated in patients with hypersensitivity to active substances or to any other component of the preparation. as well as for rosacea, acne, skin reactions after vaccination, perioral dermatitis, widespread plaque psoriasis, perianal and genital itching, varicose veins, diaper dermatitis, skin manifestations of syphilis, chickenpox, skin tuberculosis, other bacterial and fungal infections of the skin antibacterial and antifungal therapy, with herpes zoster, herpes common, molluscum contagiosum, dermatomycosis.

Structure:

Active ingredients: betamethasone, salicylic acid;
1 g of ointment contains 0.64 mg of betamethasone dipropionate, which is equivalent to 0.5 mg of betamethasone, and 30 mg of salicylic acid;
auxiliary substances: petroleum jelly, petroleum jelly.

Features of the application.

The preparation is not intended for use in ophthalmology. avoid contact with eyes, mucous membranes, wound surfaces and ulcers.
If irritation or hypersensitivity occurs during the use of the preparation, treatment should be discontinued.
In the presence of infection, appropriate therapy should be prescribed.
With the disappearance of dandruff or keratinization, treatment is continued only with corticosteroids.
Any side effects that are observed with the use of systemic corticosteroids, including inhibition of the function of the adrenal cortex, can also be observed with topical application of glucocorticosteroids, especially in children.
The systemic absorption of corticosteroids or salicylic acid with topical application will be higher if the treatment is carried out on large surfaces of the body or when using occlusive dressings. Appropriate precautions should be taken in such cases or with prolonged use, especially when treating children.
With the development of excessive dryness or increased skin irritation, the preparation  should be discontinued.
Topical corticosteroids can cause psoriasis for a variety of reasons, including recurrence of symptoms followed by the development of tolerance, the risk of pustular psoriasis and local systemic toxicity due to a decrease in the protective function of the skin. Patients with impaired liver function are more sensitive to systemic influences. Careful observation of the patient is necessary.
Topical corticosteroids can distort the clinical picture.
A relapse is possible if treatment is interrupted, as well as an exacerbation of the infection and a delay in healing.
Application of the preparation to areas with atrophied skin is contraindicated.
Application during pregnancy or lactation.
Since the safety of using topical corticosteroids for pregnant women has not been established, the appointment of these preparations is possible only if the expected benefit to the expectant mother clearly outweighs the potential threat to the fetus. preparations in this group are contraindicated for pregnant women in high doses and for a long time.
At present, it is unclear whether topical corticosteroids can penetrate into breast milk as a result of systemic absorption when applied topically, therefore, when deciding whether to stop breastfeeding or discontinue the preparation, the need to prescribe the preparation  should be taken into account.

Method of administration and dosage.

The ointment is applied in a thin layer to the affected area of ​​the skin 2 times a day, in the morning and in the evening. for some patients, a single daily application may be sufficient to achieve a satisfactory result.
The maximum daily dose should be gradually reduced to the minimum that would control symptoms.
The preparation is prescribed for children over 2 years old. The duration of treatment for children from 2 years of age should be limited to 5 days.
Children.
The preparation is prescribed for children over 2 years old.
When used in children, it is necessary to take into account the possibility of signs of suppression of the hypothalamic-pituitary-adrenal system, which occur in children more often than in adult patients, which is associated with a greater absorption of the preparation in children due to the greater value of the ratio of skin area to body weight.
In children who received topical corticosteroids, adrenal suppression, Cushing's syndrome, growth retardation, insufficient body weight gain, and increased intracranial pressure were noted.
Manifestations of suppression of the function of the adrenal cortex: low levels of cortisol in the blood plasma and lack of response to the test for stimulating the adrenal glands with the use of adrenocorticotropic hormone (ACTH) preparations. Increased intracranial pressure is manifested by protrusion of the fontanelle, headache, bilateral edema of the optic nerve head.
The use of this preparation is possible only if the expected benefit outweighs the potential risk of adverse reactions.

Overdose.

With prolonged or excessive use of local glucocorticosteroids, it is possible to suppress the pituitary-adrenal function with the development of secondary adrenal insufficiency and the appearance of symptoms of hypercortisolism, including Cushing's disease. Excessive or prolonged use of topical salicylic acid preparations may cause symptoms of salicylism.
Treatment. Appropriate symptomatic therapy is prescribed. Symptoms of acute hypercortisolism are usually reversible. If necessary, the electrolyte balance is corrected. In the case of chronic toxic effects, a gradual withdrawal of corticosteroids is recommended.
Treatment of salicizlim is symptomatic. Measures are taken to remove salicylates from the body more quickly. In case of overgrowth of resistant microorganisms, it is recommended to stop treatment with the preparation and prescribe the necessary therapy. Sodium bicarbonate is used orally to alkalize urine and increase urine output.

Adverse reactions.

When using local corticosteroids, the following side reactions can be observed: burning, itching, irritation, dry skin, folliculitis, hypertrichosis, acne-like rash, hypopigmentation, perioral dermatitis and allergic contact dermatitis.
The following adverse reactions may occur more frequently with occlusive dressings: skin maceration, secondary infection, skin atrophy, stretch marks and prickly heat.
Stretch marks and vasodilation, mainly on the face, can be the result of prolonged continuous application of the preparation.

Shelf life.

3 years.

Storage conditions.

Keep out of the reach of children at a temperature not exceeding 25 ° C.

Tags: Dermabin

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