Dona, powder for oral solution 30 sachets — Made in Ireland — Free Delivery

DONA® is prescribed to relieve symptoms of mild to moderate osteoarthritis of the knee.

Active ingredient: glucosamine sulfate.

1 sachet contains 1,884 mg of crystalline glucosamine sulfate, which is equivalent to 1,500 mg of glucosamine sulfate and 384 mg of sodium chloride.

Excipients: aspartame (E 951), sorbitol (E 420), citric acid, polyethylene glycol 4000

Hypersensitivity to glucosamine or to any of the excipients; dysfunction of the liver and kidneys in the stage of decompensation, a tendency to bleeding. DONA® should not be used in patients with shellfish allergy, since the active ingredient is obtained from shellfish.

Adult patients and elderly patients dissolve the contents of 1 sachet, equivalent to 1500 mg of glucosamine sulfate in a glass of water and take once a day, preferably with meals.

Glucosamine is not intended to treat acute pain symptoms. Symptom relief (especially pain relief) may only occur after a few weeks of use, and in some cases longer.

If no relief of symptoms has occurred after 2-3 months of administration, treatment should be reconsidered.

Before using the preparation, it is necessary to consult a doctor to exclude the presence of joint diseases for which other methods of treatment are provided.

There are no data on the use of the preparation during pregnancy and lactation; therefore, the preparation should not be used in this category of patients.

Do not use in children and adolescents (under 18 years of age), since the safety and efficacy of the preparation for such patients have not been established.

The study of the effect of the preparation on the ability to drive a car and other mechanisms has not been conducted. Care should be taken when driving and performing work requiring attention. In case of drowsiness, fatigue, dizziness or visual impairment, driving and operating machinery is prohibited.

Overdose cases were not observed with. Given the acute and chronic toxicity studies in animals, symptoms of toxicity are unlikely to occur even when used in doses 200 times the therapeutic dose. However, in case of an overdose, the manifestations of adverse reactions may increase, therefore, it is worthwhile to carry out symptomatic treatment aimed at restoring the water-electrolyte balance.

The most common adverse reactions associated with glucosamine use are nausea, abdominal pain, indigestion, flatulence, constipation, diarrhea, headache, fatigue, and drowsiness. These adverse reactions are usually transient and mild.

There are limited data on the possible interaction of preparations with glucosamine, however, there was an increase in INR (international normalized recovery) with the use of oral vitamin K antagonists.Therefore, patients receiving oral vitamin K antagonists should be closely monitored during the initiation or discontinuation of glucosamine therapy. Concomitant treatment with glucosamine can enhance absorption and, therefore, the concentration of tetracyclines in serum. However, the clinical relevance of this interaction is likely to be limited.

Given the fact that there are only limited data on the possible interaction of glucosamine, special attention should be paid to any modified reaction to changes in the concentration of concomitant preparations used in serum.

Keep out of the reach of children at a temperature not exceeding 30 ° C.

Shelf life is 3 years.