Glucophage XR 1000 mg 60 tablets — Made in France — Free Delivery

Product description

Glucophage XR tablets are indicated for:

• Reducing the risk of or delaying the onset of type 2 diabetes mellitus in overweight adults.
• Treatment of type 2 diabetes mellitus in adults, especially in overweight patients, when diet and exercise alone do not provide adequate glycemic control.

Composition

Active substance: metformin;

1 coated tablet contains metformin hydrochloride 1000 mg;

Excipients: sodium carmellose, hypromellose 100000 CPS, magnesium stearate.

Contraindications

• hypersensitivity to metformin or to any other component of the preparation;
• any type of acute metabolic acidosis (eg, lactic acidosis, diabetic ketoacidosis)
• diabetic coma;
• severe renal failure (glomerular filtration rate (GFR) <30 ml / min)
• acute conditions occurring with the risk of developing renal dysfunction, such as: dehydration, severe infectious diseases, shock;
• diseases that can lead to the development of tissue hypoxia (especially acute diseases or exacerbations of a chronic disease) decompensated heart failure, respiratory failure, recent myocardial infarction, shock;
• liver failure, acute alcohol poisoning, alcoholism.

Mode of application

The preparation Glucophage XR 1000 mg is used once a day with meals in the evening. The maximum recommended dose is 2 tablets per day.

Application features

Pregnant

In the case of planning pregnancy, as well as in case of pregnancy, it is recommended not to use metformin for the treatment of disorders of glycemic control or diabetes.

Children

The preparation should not be used in children, since there are no clinical data for this age group of patients.

Drivers

Carefully

Overdose

When using the preparation  at a dose of 85 g, the development of hypoglycemia was not observed. However, in this case, the development of lactic acidosis was observed. A significant excess of the dose of metformin or associated risk factors can lead to the development of lactic acidosis. Lactic acidosis is a medical emergency. If lactic acidosis develops, preparation treatment should be discontinued and the patient should be urgently hospitalized. The most effective measure for removing lactate and metformin from the body is hemodialysis.

Side effects

From the nervous system. Often: taste disturbance.

From the digestive tract. Very common: disorders of the digestive system, such as: nausea, vomiting, diarrhea, abdominal pain, lack of appetite. Most often, these side effects occur at the beginning of treatment and in most cases disappear spontaneously. To prevent the occurrence of side effects from the gastrointestinal tract, a slow increase in the dose of the preparation is recommended.

Interaction

Alcohol. Acute alcohol intoxication is associated with an increased risk of lactic acidosis, especially in cases of fasting or a low-calorie diet, as well as in liver failure. When treating with Glucophage XR, you should avoid taking ethanol and medicines containing ethanol.

Combinations to be used with caution. Medicines that have a hyperglycemic effect (GCS of systemic and local action, sympathomimetics). It is necessary to monitor blood glucose levels more often, especially at the beginning of treatment. During and after the termination of such combination therapy, it is necessary to adjust the dose of Glucophage XR under the control of the glycemic level.

Storage conditions

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children!

Shelf life is 3 years.