Ketorol Express 10mg,10 dispersible tablets — Made in India — Free Delivery
(Ketorol Express )
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Description Ketorol Express 10mg,10 dispersible tablets — Made in India — Free Delivery
Product description
Ketorol Express is indicated for short-term (no more than 5 days) treatment of pain of moderate intensity, as well as acute pain of various origins, including postoperative pain.
Composition
Active ingredient: ketorolac tromethamine;
1 tablet contains ketorolac tromethamine 10 mg;
Excipients: microcrystalline cellulose, silicon dioxide, butylhydroxyanisole (E 320), mannitol (E 421), crospovidone, sucralose, magnesium stearate, dye (Lake Of Quinoline Yellow WS), flavor (Spearmint Flavor).
Contraindications
- Hypersensitivity to ketorolac or to any component of the preparation;
- patients with active peptic ulcer disease, with recent gastrointestinal bleeding or perforation, with a history of peptic ulcer disease or gastrointestinal bleeding;
- bronchial asthma, rhinitis, angioedema or urticaria caused by the use of acetylsalicylic acid or other NSAIDs (due to the possibility of severe anaphylactic reactions);
- history of bronchial asthma;
- do not use as an analgesic before and during surgery and after manipulations on the coronary vessels;
- severe heart failure;
- nasal polyposis with complete or partial obstruction, angioedema or bronchospasm;
- do not use in patients who have had surgery with a high risk of hemorrhage or incomplete stop of bleeding and patients receiving anticoagulants, including low doses of heparin (2500-5000 units every 12 hours);
- hepatic or moderate / severe renal failure (serum creatinine clearance more than 160 μmol / l);
- ketorolac is contraindicated during labor and childbirth, because as a result of its inhibitory effect on prostaglandin synthesis, it can negatively affect fetal circulation and suppress uterine contraction, thereby increasing the risk of uterine bleeding;
- suspected or confirmed cerebrovascular bleeding, hemorrhagic diathesis, including bleeding disorders and high risk of bleeding;
- concomitant treatment with other NSAIDs (including selective cyclooxygenase inhibitors), acetylsalicylic acid, warfarin, pentoxifylline, probenecid or lithium salts;
- hypovolemia, dehydration;
- the risk of renal failure due to a decrease in fluid volume.
Mode of application
Ketorol Express in the form of tablets that are dispersed in the mouth should only be taken with dry hands.
The tablet should be placed on the tongue, where it immediately begins to dissolve. Keep in the mouth for a few seconds until it is completely dissolved, if desired, you can drink it with water.
Taking tablets that are dispersed in the oral cavity, do not require drinking water, do not affect saliva production, allow patients with deviations in the act of swallowing with behavioral or neurological disorders to take the preparation.
To prevent digestive disorders, it is advisable to take the preparation with or after a meal (main meal or snack) or with antacids.
Application features
Pregnant
Contraindicated.
Children
Do not use in children under 16 years of age.
Drivers
Some patients may experience dizziness, drowsiness, blurred vision, headaches, vertigo, insomnia, or depression while using ketorolac. If patients feel the above or other similar side effects, they should not drive or operate machinery.
Overdose
Symptoms following an acute NSAID overdose are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain, which are usually reversible with supportive treatment. Gastrointestinal bleeding may occur. Rarely, hypertension, acute renal failure, respiratory depression, and coma may occur. When using NSAIDs in therapeutic doses, anaphylactoid reactions have been reported, which can occur after an overdose.
Side effects
From the gastrointestinal tract (GIT), including: heartburn, stomatitis, nausea, vomiting, abdominal pain, dyspepsia, constipation / diarrhea, flatulence, feeling of fullness, ulcers in the gastrointestinal tract (in the stomach / duodenum), major bleeding / perforation <> <> Other disorders: impaired renal function, dizziness, drowsiness, anemia, edema, increased levels of liver enzymes, headaches, arterial hypertension, increased bleeding time, pain at the injection site, itching, purpura, rash, tinnitus, sweating ...
Interaction
Ketorolac is largely bound to blood plasma proteins (on average, 99.2%). There is no data from studies in animals or humans that ketorolac tromethamine induces or inhibits liver enzymes, is able to metabolize it or other preparations.
Reported isolated cases of seizures during the simultaneous use of ketorolac tromethamine and anticonvulsants (phenytoin, carbamazepine).
Storage conditions
Store in its original packaging at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Shelf life is 2 years.
Tags: Ketorol
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