Magurol 4mg 20 tablets — Made in Cyprus — Free Delivery
(Magurol 4mg )
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Description Magurol 4mg 20 tablets — Made in Cyprus — Free Delivery
Product description
Magurol tablets are indicated for:
- arterial hypertension.
- Benign prostatic hyperplasia.
Compound
Active ingredient: doxazosin;
1 tablet contains doxazosin mesilate 4.86 mg equivalent to doxazosin 4 mg;
Excipients: lactose monohydrate, microcrystalline cellulose, sodium starch (type A), magnesium stearate, sodium lauryl sulfate.
Contraindications
- hypersensitivity to the active substance or to quinazoline derivatives or to any of the excipients of the preparation indicated in the section;
- cases of orthostatic hypotension with a history of BPH and concomitant upper urinary tract obstruction, chronic urinary tract infections and the presence of bladder stones;
- during lactation (only when used for the treatment of arterial hypertension, arterial hypotension (applies only to patients with BPH);
Doxazosin as monotherapy is contraindicated in patients with bladder overflow or anuria with or without progressive renal failure.
Mode of application
The preparation can be taken both in the morning and in the evening.
The preparation is used orally.
Arterial hypertension. The preparation should be used 1 time per day. The initial dose is 1 mg to minimize the risk of orthostatic hypotension and/or syncope. After 1-2 weeks of initial therapy, the dose can be increased to 2 mg, and then, if necessary, to 4 mg. In most patients, response to therapy is observed when using the preparation at a dose of 4 mg below. If necessary, the dose can be increased to 8 mg up to the maximum recommended dose of 16 mg.
Benign prostatic hyperplasia. The recommended starting dose of doxazosin is 1 mg once daily to minimize the risk of orthostatic hypotension and/or syncope. Depending on the individual characteristics of the patient's urodynamics and symptoms of BPH, the dose can be increased to 2 mg, then to 4 mg and up to the maximum recommended dose of 8 mg. The recommended dose selection interval is 1-2 weeks. The recommended dose is 2-4 mg per day.
Application features
pregnant
The preparation should be used only when the potential benefits of treatment, in the opinion of the physician, justify the potential risk.
Children
The safety and efficacy of the preparation in children have not been studied.
Drivers
The ability to drive and use machines may be impaired, especially at the start of treatment.
Overdose
If an overdose of the preparation has led to arterial hypotension, the patient should be urgently placed on his back with his head down. In some cases, other symptomatic measures can be taken.
If symptomatic measures are insufficient, plasma substitutes should be used first to treat shock. After that, if necessary, vasoconstrictor preparations should be used. The state of renal function should be monitored and, if necessary, supportive measures should be taken.
Hemodialysis is indicated because doxazosin is highly protein bound.
Side effects
Infections and infestations: respiratory tract infections, urinary tract infections.
From the blood and lymphatic system: leukopenia, thrombocytopenia.
From the immune system: allergic reactions.
Metabolic and nutritional disorders: gout, increased appetite, lack of appetite.
Mental disorders: agitation, depression, anxiety, insomnia, nervousness.
From the nervous system: drowsiness, dizziness, headache, stroke, hypesthesia, syncope, tremor, orthostatic dizziness, paresthesia.
On the part of the organ of vision: blurred vision, intraoperative atonic iris syndrome.
On the part of the organs of hearing and balance: vertigo, tinnitus.
From the side of the heart: tachycardia, tachycardia, angina pectoris, myocardial infarction, bradycardia, arrhythmia.
From the side of the vessels: arterial hypotension, orthostatic arterial hypotension, hot flashes.
From the respiratory system, chest and mediastinum: bronchitis, cough, shortness of breath, rhinitis, epistaxis, increased existing bronchospasm.
From the gastrointestinal tract: abdominal pain, dyspepsia, dry mouth, nausea, constipation, flatulence, vomiting, gastroenteritis, diarrhea.
From the digestive system: abnormal liver function, cholestasis, hepatitis, jaundice.
From the skin and subcutaneous tissue: itching, rash, urticaria, alopecia, purpura.
From the musculoskeletal system and connective tissue: back pain, myalgia, arthralgia, muscle spasms, muscle weakness.
From the kidneys and urinary system: cystitis, urinary incontinence, dysuria, frequent urination, hematuria, polyuria, increased diuresis, urination disorders, nocturia.
From the reproductive system and mammary glands: impotence, gynecomastia, priapism, retrograde ejaculation. Interaction
Co-administration of doxazosin with PDE-5 inhibitors may cause symptomatic hypotension in some patients.
Storage conditions
Store in original packaging at temperatures not exceeding 25°C.
Keep out of the reach of children.
Shelf life - 5 years.
Tags: Magurol
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