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  • Marvelon 63 tablets — Made in Netherlands — Free Delivery

Marvelon 63 tablets — Made in Netherlands — Free Delivery

(Marvelon )
Marvelon 63 tablets — Made in Netherlands — Free Delivery
Marvelon 63 tablets — Made in Netherlands — Free Delivery
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NV Organon Brand: NV Organon
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Description Marvelon 63 tablets — Made in Netherlands — Free Delivery

Indications

Prevention of pregnancy (contraception).

Application

General rules for taking Marvelon.
Tablets should be taken daily for 21 days in accordance with the indicated order on the package without interruption, at approximately the same time, one tablet per day, with a small amount of liquid if necessary. After a 21-day course, take a break for 7 days. During this period, a menstrual-like reaction occurs, the duration of which may be shorter and the intensity lower than normal menstruation. As a rule, it begins on the 2-3rd day after taking the last tablet and may continue until the next course of the preparation (the next package) is taken. Taking the pills from the next pack begins after 7 days of the “no pills” period.
Getting Started with Marvelon
Hormonal contraceptives were not used in the previous period (last month)
The tablets are started on the 1st day of the natural cycle (that is, on the first day of menstrual bleeding). You can start taking it from the 2-5th day, however, in this case, during the first cycle, it is recommended to additionally use a barrier method of contraception during the first 7 days of taking the tablets.
Switching from another PDA
It is desirable that a woman start taking Marvelon the day after taking the last active tablet of the previous combined contraceptive, but no later than the day after the break in taking the tablets or placebo of the previous combined contraceptive.
Switching from a progestogen-only method (mini-pills, injections, implants)
A woman can start taking Marvelon on any day after stopping the use of the minipill (in the case of an implant, on the day of its removal, in the case of injections, instead of the next injection). However, in all cases, it is advised to additionally use a barrier method of contraception during the first 7 days of taking the pills.
After an abortion in the first trimester
A woman can start taking Marvelon immediately. In this case, she does not need to use additional methods of contraception.
After childbirth or abortion in the second trimester
Women should be advised to start taking Marvelon on the 21st or 28th day after giving birth or having an abortion in the second trimester. With a later start of taking, you should additionally use a barrier method of contraception during the first 7 days of taking the tablets. However, if sexual intercourse has already occurred, then before starting the use of the PDA, it is necessary to establish the presence of pregnancy or wait for the next menstruation.
What to do if you miss taking your pills
If the delay in taking the pill did not exceed 12 hours, the contraceptive effect of Marvelon will remain throughout the entire period of taking the preparation. If, for any reason, a woman has forgotten to take a Marvelon tablet, it must be taken as soon as she finds out. In the future, taking the tablets from this pack should be continued as usual.
If the delay in taking the pill exceeds 12 hours, the contraceptive effect may decrease. In case of skipping pills, you can be guided by 2 basic rules:
taking pills cannot be interrupted for more than 7 days;
to achieve an adequate inhibitory effect of the preparation on the axis of the hypothalamus - pituitary gland - ovaries, continuous administration of the preparation for 7 days is necessary.
In accordance with this, it is recommended to follow such advice.
First week
A woman should take the last missed tablet as soon as she remembers the missed one, even if she has to take 2 tablets at the same time. She then continues to take her tablets at the usual time. In addition, a barrier method of contraception must be used for the next 7 days. If sexual intercourse has taken place within the previous 7 days, the possibility of pregnancy should be considered. The more pills missed, and the closer the missed pill is to the usual pill-free period, the higher the risk of pregnancy.
Second week
A woman should take the last missed tablet as soon as she remembers the missed one, even if she has to take 2 tablets at the same time. She then continues to take her tablets at the usual time. If the woman has taken her pills correctly in the 7 days before the miss, then there is no need to use additional contraceptive measures. Otherwise, or if more than 1 tablet is missed, an additional barrier method of contraception should be used for 7 days.
Third week
The risk of reduced contraceptive reliability increases as the pill break approaches. However, if the pill regimen is followed, a decrease in the level of contraception can be avoided. If one of the following rules is followed, then there will be no need to use additional contraceptives, provided that the woman has taken the pills correctly within 7 days before the pass. If not, then the woman should adhere to the first of the following rules and use additional methods of protection for the next 7 days.
A woman should take the last missed tablet as soon as she remembers the missed one, even if she has to take 2 tablets at the same time. She then continues to take her tablets at the usual time. Tablets from the next package should be started immediately after the previous one has ended, that is, there should not be a break between taking tablets from different packages. It is unlikely that a woman will begin to have a menstrual flow before completing the pills from the second pack, although smearing or sudden bleeding may be noted in the process of taking the pills.
The woman may also be advised to stop taking the pills in the pack she is using. In this case, the break should be 7 days, including the days of skipping tablets; taking the tablets should start with the next package. If a woman misses her pills and does not experience menstrual flow during the first usual break in taking the preparation, pregnancy should be assumed.
Recommendations in case of vomiting
If vomiting occurs within 3-4 hours after taking the tablet, then incomplete absorption of the preparation is possible. In this case, it is advisable to follow the recommendations regarding skipping the pill. If a woman does not want to change her usual preparation regimen, she needs to take an additional tablet from another package.
How to change or delay your period
To delay the onset of menstruation, a woman should continue taking Marvelon from a new package and not take a break. If desired, the period of admission can be extended until the end of taking the tablets from the second package. This may cause sudden short-term bleeding or smearing. Regular intake of Marvelon is resumed after the usual 7-day break in taking the tablets.
In order to change the period of menstruation - to move its beginning to another day of the week, a woman can be recommended to reduce the period without taking pills by the required number of days. The shorter this period, the more likely there will be no withdrawal bleeding and smearing or short-term bleeding during the next pack (as with a delay in menstruation).

Contraindications

Taking combined contraceptives is contraindicated in any of the following conditions. if any of these conditions occur during the use of combined contraceptives for the first time, the preparation should be stopped immediately:
  • thrombosis (venous or arterial), including a history of indications (for example, deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular disorders);
  • the presence, including in the anamnesis, of precursors of thrombosis (for example, angina pectoris, cerebrovascular accident);
  • migraine with focal neurological symptoms;
  • diabetes mellitus with vascular complications;
  • the presence of thrombosis;
  • pancreatitis or previous pancreatitis, accompanied by high hypertriglyceridemia;
  • severe liver disease, including a history of indications (before normalization of liver function tests);
  • liver tumors (benign or malignant), including a history;
  • hormone-dependent malignant tumors (established or suspected, for example, tumors of the genital organs or mammary glands);
  • vaginal bleeding of unknown etiology;
  • established or suspected pregnancy;
  • hypersensitivity to any component of the preparation.
COCs should be taken with caution in any of the following conditions: obesity (body mass index 30 kg/m2); increased blood pressure; atrial fibrillation; heart valve disease; dyslipoproteinemia; liver and gallbladder disease; Crohn's disease and ulcerative colitis; sickle cell anemia; systemic lupus erythematosus; hemolytic uremic syndrome; epilepsy; smoking over the age of 35; prolonged immobilization, significant surgical interventions; fibrocystic mastopathy; fibromyoma of the uterus; diabetes; congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndrome); chloasma (women who are prone to pigmentation are advised to avoid exposure to the sun or ultraviolet radiation while taking COCs).

Side effects

There are reports of the following side effects (however, their connection with the use of the preparation has not been confirmed or refuted): soreness and swelling of the mammary glands and the occurrence of secretion; headache, migraine; change in libido; depressive state; intolerance to contact lenses; nausea; vomit; changes in vaginal secretion; different skin manifestations; fluid retention in the body; change in body weight; hypersensitivity reactions.

special instructions

The daily dose of lactose contained in the tablet is so low (80 mg) that even women sensitive to lactose will not feel any disturbance.

Warning

If any of the conditions/risk factors listed in the CONTRAINDICATIONS section are present, the benefits and risks of COC use should be considered by the clinician on a woman-by-woman basis and discussed with the patient before she decides to take this preparation. In the event of an exacerbation, intensification, or first appearance of any of these conditions, a woman should consult a doctor. The doctor must determine whether to continue or stop taking COCs.
Medical examination/consultation
Before starting or resuming oral combined contraceptives, a thorough medical examination of the woman should be carried out, including taking a complete history and performing instrumental studies, paying special attention to possible contraindications. Such an examination must be repeated at least once a year during the entire intake of combined contraceptives. Periodic medical evaluation is important for contraindications (eg cerebrovascular accident) or risk factors (eg family history of venous or arterial thrombosis) that may first occur while taking contraceptives. The frequency and nature of such examinations is set for each woman individually, but in general they should include measurement of blood pressure, examination of the mammary glands, abdominal and pelvic organs, cytological examination of the cervical epithelium and appropriate laboratory tests.
Women should be taught that oral contraceptives do not protect against HIV/AIDS and other sexually transmitted diseases.
Reduced efficiency
The effectiveness of COCs may be reduced in case of missing pills (see USE), gastrointestinal disturbances, or when taking certain preparations at the same time (see INTERACTIONS).
Impaired menstrual control
During the use of COCs, irregular minor (smearing) or heavy bleeding may be noted, especially during the first months of use. Therefore, the evaluation of any violations of the control of the menstrual cycle can be carried out only after an adaptation period of approximately 3 cycles.
If irregular bleeding persists or occurs after previous regular cycles, probable non-hormonal causes should be considered and the necessary diagnostic tests should be performed to rule out pregnancy or tumor; possible curettage.
Some women may not experience withdrawal bleeding during their pill-free period. If COCs were used as recommended, the chances of pregnancy are low. However, if violations of these recommendations were noted in the period before the first absence of bleeding in the period without taking pills, or if there is no bleeding twice in a row, pregnancy should be excluded before continuing to take COCs.
The use of the preparation  during pregnancy and / or lactation. Pregnancy is a contraindication for the use of Marvelon. If a woman becomes pregnant while taking Marvelon, further use should be stopped immediately. Studies have not revealed an increased risk of pathology in children born to mothers who took COCs during pregnancy, nor a teratogenic effect from COCs that were inadvertently taken at the beginning of pregnancy.
Estrogens affect lactation because they can reduce the amount and composition of breast milk, but there was no evidence of a negative effect on the health of infants. However, it is not recommended to use PDA during breastfeeding, if necessary, the use of PDA should completely stop breastfeeding.
Influence on the ability to drive vehicles. It does not affect the ability to concentrate.

Interactions

Interactions between oral contraceptives and other preparations can lead to sudden bleeding and / or weakening of the contraceptive effect of the preparation. interactions can be noted with preparations that induce microsomal enzymes, which can lead to increased metabolism of sex hormones. such preparations include phenytoin, barbiturates, primidone, carbamazepine, rifampicin, and possibly also oxcarbazepine, topiramate, felbamate, ritonavir, griseofulvin, and preparations containing St. John's wort. the effectiveness of the preparation may also decrease with the parallel administration of certain antibiotics, such as penicillins and tetracyclines. these preparations reduce the enterohepatic circulation of estrogen, which leads to a decrease in the concentration of ethinyl estradiol.
Women taking any of these preparations should temporarily use a barrier method of contraception in addition to the COC or choose another method of protection against unwanted pregnancy. Women taking antibiotics (except rifampicin and griseofulvin) need to use a barrier method while taking the corresponding preparation and for 7 days after its withdrawal. When taking preparations that stimulate microsomal enzymes, it is necessary to use a barrier method in addition to COC during the entire period of treatment and for another 28 days after discontinuation. If the administration of the preparation must be continued, and the tablets in the PDA pack have already run out, the next pack should be started immediately, without the usual interruption.
COCs may interfere with the metabolism of other preparations. Accordingly, the concentration of such preparations (for example, cyclosporine) in blood plasma and in tissues may change.
Note. To determine the possible interaction, you should study the information regarding the prescription of the preparation, which is used in parallel.
Laboratory tests. Contraceptive steroids may interfere with the results of certain laboratory tests, including biochemical parameters of the function of the liver, kidneys, thyroid, adrenal glands, the level of proteins (carriers) in the blood serum, for example, corticosteroid-binding globulin and / or lipid / lipoprotein fraction, indicators of carbohydrate metabolism, coagulation and fibrinolysis. Changes usually remain within the normal range.

Overdose

No significant adverse effects have been reported in overdose. the following symptoms may occur: nausea, vomiting, and in girls, slight bleeding from the vagina. there is no antidote. if necessary, symptomatic therapy is indicated.

Storage conditions

In a place protected from light and moisture at a temperature of 2-30 ° C.

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