Midiana 21 tablets — Made in Hungary — Free Delivery
(Midiana )
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Description Midiana 21 tablets — Made in Hungary — Free Delivery
Product description
Midian tablets are indicated for oral contraception.
Compound
Active ingredients: drospirenone, ethinyl estradiol;
1 tablet contains drospirenone 3 mg ethinyl estradiol 0.03 mg;
Excipients: lactose, corn starch, corn starch, povidone K-25, magnesium stearate;
Shell: Opadray II white (polyvinyl alcohol, titanium dioxide (E 171), macrogol, talc, lecithin (soy)).
Contraindications
Combined hormonal contraceptives (CHCs) should not be used if any of the following conditions are present. If any of these conditions occur for the first time during the use of CHC, the preparation should be stopped immediately.
- the presence or risk of developing venous thromboembolism (VTE);
- the presence or risk of developing arterial thromboembolism (ATE);
- diabetes mellitus with vascular complications;
- severe arterial hypertension;
- severe dyslipoproteinemia;
- the presence of severe liver disease at present or in history, until the indicators of liver function have returned to the normal range;
- severe renal failure or acute renal failure;
- the presence of liver tumors at present or in history (benign or malignant);
- or suspected malignant tumors (eg, genital or mammary glands) dependent on sex hormones;
- vaginal bleeding of unknown etiology;
- hypersensitivity to the active substances or to any of the components of the preparation;
Mode of application
Tablets should be taken every day at about the same time, if necessary, with a small amount of liquid, in the sequence indicated on the blister pack. It is necessary to take 1 tablet per day for 21 consecutive days. Each subsequent pack should begin after a seven-day break in taking the tablets, during which menstrual-like bleeding usually occurs. It usually starts 2-3 days after the last pill and may not end before the next pack starts.
Application features
pregnant
Contraindicated.
Children
The preparation is indicated for use as prescribed by a doctor only after the onset of stable menstruation.
Overdose
So far, there is no data on the combined overdose of drospirenone and ethinyl estradiol. Based on general experience with combined oral contraceptives, overdose may cause nausea, vomiting, or, in young girls, vaginal bleeding. There is no specific antidote; treatment should be symptomatic.
Side effects
Mental disorders. Emotional lability.
Nervous system. Headache.
From the gastrointestinal tract. Nausea.
From the reproductive system and mammary glands. Soreness of the mammary glands, metrorrhagia, amenorrhea.
Interaction
COCs may affect the metabolism of certain active substances. Accordingly, plasma and tissue concentrations may either increase (eg, cyclosporine) or decrease (eg, lamotrigine).
Based on in vivo interaction studies in female volunteers taking omeprazole, simvastatin and midazolam as substrate markers, it was found that a clinically significant interaction of drospirenone at a dose of 3 mg with other preparations that are induced by cytochrome P450 is unlikely.
Clinical data suggest that ethinylestradiol inhibits the clearance of CYP1A2 substrates, which in turn causes a slight (eg, theophylline) or moderate (eg, tizanidine) increase in their plasma concentrations.
Storage conditions
Store at a temperature not exceeding 25°C in the original packaging to protect from light.
Keep out of the reach of children.
Shelf life - 2 years.
Tags: Midiana
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