Novagra 100 mg 8 tablets — Made in India — Free Delivery

Product description

Novagra is recommended for men with erectile dysfunction, which is defined as the inability to achieve or maintain an erection of the penis necessary for successful intercourse.

For the effective action of the preparation Novagra, you need sexual arousal.

Compound

Active substance: sildenafil;

1 tablet contains sildenafil citrate, equivalent to sildenafil 50 mg or 100 mg;

Excipients: calcium hydrogen phosphate, microcrystalline cellulose, croscarmellose sodium, povidone, colloidal silicon dioxide, magnesium stearate, instakot IC-S-091 (pink).

Contraindications

• hypersensitivity to the active substance or to any of the excipients of the preparation;
• simultaneous use with nitric oxide donors (such as amyl nitrite) or nitrates in any form is contraindicated, since it is known that sildenafil affects the pathways of nitric oxide / cGMP metabolism and potentiates the hypotensive effect of nitrates;
• the simultaneous use of PDE-5 inhibitors (including sildenafil) with guanylate cyclase stimulants such as riociguat is contraindicated because it can lead to symptomatic hypotension;
• conditions for which sexual activity is not recommended (for example, severe cardiovascular disorders such as unstable angina or severe heart failure);
• loss of vision in one eye due to non-arterial anterior ischemic neuropathy of the optic nerve, regardless of whether this pathology is associated with previous use of PDE-5 inhibitors or not;
• the presence of diseases such as severe liver dysfunction, arterial hypotension (blood pressure below 90/50 mm Hg), recent stroke or myocardial infarction, and known hereditary degenerative retinal diseases such as retinitis pigmentosa (a small number of these patients have genetic disorders Retinal PDE), since the safety of sildenafil has not been studied in these patient subgroups.

Mode of application

The preparation is administered orally.

The recommended dose is 50 mg and is applied as needed about 1 hour before sexual activity. Depending on the effectiveness and tolerability of the preparation, the dose can be increased to 100 mg or reduced to 25 mg. The maximum recommended dose is 100 mg.

The frequency of application of the maximum recommended dose of the preparation is 1 time per day. When using the preparation  Novagra with meals, the effect of the preparation may occur later than when it is used on an empty stomach. For the effective action of the preparation, sexual arousal is necessary.

Application features

Pregnant

The preparation is not intended for use by women.

Children

Not indicated for use in children under the age of 18.

Drivers

Studies of the effect of the preparation on the ability to drive vehicles or work with other mechanisms have not been conducted. Since clinical studies with sildenafil have reported cases of dizziness and visual disturbances, before driving a vehicle or working with machinery, it is necessary to find out the individual response to the use of Novagra.

Overdose

In the course of clinical studies with the participation of volunteers, with the use of a single dose of sildenafil up to 800 mg, adverse reactions were similar to those observed with the use of sildenafil in lower doses, but were more frequent and more severe. The use of sildenafil at a dose of 200 mg did not lead to an increase in efficacy, but caused an increase in the number of cases of adverse reactions (headache, hot flashes, dizziness, dyspepsia, nasal congestion, visual disturbances).

In case of overdose, if necessary, resort to the usual supportive measures. An acceleration of the clearance of sildenafil during hemodialysis is unlikely due to the high degree of binding of the preparation to blood plasma proteins and the lack of elimination of sildenafil in the urine.

Side effects

The most commonly reported adverse reactions were headache, flushing, dyspepsia, nasal congestion, back pain, dizziness, nausea, hot flashes, visual disturbances, cyanopsia, and blurred vision.

Interaction

Sildenafil metabolism occurs predominantly with the participation of the ZA4 isoform (major pathway) and the 2C9 isoform (minor pathway) of cytochrome P450 (CYP). Therefore, inhibitors of these isoenzymes can reduce the clearance of sildenafil, and inducers of these isoenzymes can increase the clearance of sildenafil.

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C, out of the reach of children.

Shelf life is 2 years.