Otofa ear drops 26 mg/ml, 10ml — Made in France — Free Delivery

Pharmacodynamic parameters. The activity of rifamycin is directed to microorganisms (gram-positive and gram-negative) that cause pathology of the middle ear of an infectious and inflammatory nature.

Rifamycin is a natural antibiotic produced by Streptomyces mediterranei. Inhibits DNA-dependent RNA synthesis and protein synthesis in prokaryotic cells, blocking the initiation of RNA polymerase transcription.

The spectrum of action of rifamycin includes staphylococci, streptococci of groups A, B, C, G, peptostreptococci, Haemophilus influenzae, gonococci and meningococci, clostridia (C. difficile, C. perfringens), anthrax bacilli, pathogens of brucellosis, listeriosis , mycobacteria, chlamydia, legionella, bacteroids, fusobacteria and pasteurella, Cutibacterium acnes, Moraxella catarrhalis, as well as Rhodococcus equi and Haemophilus ducreyi.

Bacteria of the intestinal group and atypical mycobacteria have resistance to rifamycin.

There is no activity of rifamycin against Pseudomonas aeruginosa (the reasons for at least one third of the infectious pathology included in the indications for the use of Otof).

Pharmacokinetic parameters. Not studied due to insignificant absorption of the preparation into the systemic circulation.

Topical therapy for some types of otorrhea:

chronic otitis media in the stage of exacerbation (including violation of the integrity of the membrana tympani);

isolated purulent lesion of membrana tympani;

after surgery on the middle ear.

Local - the introduction of drops into the external auditory canal. adults 5 drops, children 3 drops in the affected ear 2 times a day (morning and evening). the introduction is not carried out under pressure.

With the help of an attic cannula, it is possible to use Otof as a solution for washing cavum tympani.

The duration of therapy (on average 1 week) is individual, determined by the nature and severity of the pathology.

Before instilling the preparation into the ear, it is necessary to warm the bottle in the hands to body temperature. With the introduction of drops, the earlobe is slightly pulled back; the patient's head should be tilted (for about 5 minutes).

At the end of the treatment, it is necessary to dispose of the bottle.

Hypersensitivity to the active substance of the preparation or any of its constituents.

Allergic reactions (including anaphylaxis, bronchial smooth muscle spasm, eczema, rashes and other skin reactions).

The eardrum may turn pink.

When using otof, the approved guidelines for the proper use of antibacterial agents should be followed.

With the topical use of antibacterial agents, it is possible to develop sensitization to the active substance, followed by a systemic reaction.

In the event of a skin rash or other manifestations of a systemic allergy, preparation therapy should be discontinued immediately.

The solution is not administered orally or by injection.

Protect from contact of the skin (ear, fingers) with the dropper bottle (in order to prevent infection).

If the manifestations of the disease persist within 10 days of preparation therapy, a second consultation with a doctor is required.

There are no age restrictions.

After consulting a doctor, it can be used during pregnancy and lactation.

Does not change the reaction rate when driving vehicles or other mechanisms.

Contact with clothing may cause stains.

Combined use with any other topical preparations is not recommended.

Not found. the probability of an overdose is extremely low due to the insignificant absorption of the preparation.

At a temperature of ≤25 ° C.