Paraplexin, solution for injections 5 mg/ml, 1ml x 10 ampoules — Made in Ukraine — Free Delivery

Product description 

• diseases of the peripheral nervous system: mono- and polyneuropathy, polyradiculopathy, myasthenia gravis and myasthenic syndrome of various etiologies;
• diseases of the central nervous system (CNS): bulbar paralysis and paresis; the recovery period of organic lesions of the central nervous system, which are accompanied by motor disorders.

Compound

The active substance is ipidacrine hydrochloride monohydrate (1 ml of solution contains 5 mg of ipidacrine hydrochloride monohydrate in terms of anhydrous substance).

The excipient is water for injection.

Contraindications

• hypersensitivity to ipidacrine;
• epilepsy;
• extrapyramidal disorders with hyperkinesis;
• angina;
• severe bradycardia;
• bronchial asthma;
• vestibular disorders;
• mechanical obstruction of the intestines and urinary tract;
• peptic ulcer of the stomach or duodenum in the acute stage.

Mode of application

The solution for injection is administered intramuscularly or subcutaneously. The dose and duration of treatment should be determined individually, depending on the severity of the disease.

Diseases of the peripheral nervous system

Mono- and polyneuropathy of various origins: subcutaneously or intramuscularly inject 5-15 mg 1-2 times a day, the course of treatment is 10-15 days (in severe cases, up to 30 days); further treatment should be continued in the tablet form of ipidacrine.

Myasthenia and myasthenic syndrome: subcutaneously or intramuscularly inject 5-30 mg 1-3 times a day, followed by the transition to a tablet form. The general course of treatment is 1-2 months. If necessary, the treatment can be repeated several times with a break between courses of 1-2 months.

Diseases of the central nervous system

Bulbar paralysis and paresis: subcutaneously and intramuscularly 5-15 mg 1-2 times a day, the course of treatment is 10-15 days, if possible, you should switch to a tablet form.

The recovery period for organic lesions of the central nervous system

Intramuscularly 10-15 mg 1-2 times a day, the course of treatment is up to 15 days, then, if possible, 1-2 times a day.

Application features

pregnant

"Paraplexin®" increases the tone of the uterus and can cause premature birth, therefore, during pregnancy, the use of the preparation is contraindicated.

During lactation, the use of the preparation is also contraindicated.

Children

There are no systematized data on the use of the parenteral form of ipidacrine hydrochloride in children (under the age of 18 years), therefore, it should not be used in children.

Drivers

During the period of treatment, it is necessary to refrain from driving a car, as well as from engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Overdose

Symptoms: bronchospasm, lacrimation, increased sweating, pupillary constriction, nystagmus, increased peristalsis of the gastrointestinal tract, spontaneous defecation and urination, vomiting, jaundice, bradycardia, impaired intracardiac conduction, arrhythmias, lowering blood pressure, anxiety, anxiety, agitation, fear , ataxia, convulsions, coma, speech disorder, drowsiness, general weakness.

Treatment6, symptomatic therapy should be used, m-anticholinergics should be used: atropine, cyclodol, metacin and others.

Side effects

From the side of the cardiovascular system: increased heart rate, decreased heart rate.

From the nervous system: when using high doses - dizziness, headache, drowsiness, general weakness, convulsions.

On the part of the respiratory system: increased separation of bronchial secretions, bronchospasm.

From the digestive system: increased salivation, nausea; when using high doses - vomiting, diarrhea, jaundice, chest pain.

From the side of the skin and subcutaneous tissues: increased sweating; allergic reactions, including rash, itching, urticaria, angioedema.

From the reproductive system: increased tone of the uterus.

In case of development of undesirable side effects, the dose should be reduced or the use of the preparation should be interrupted for a short time (for 1-2 days). Salivation and a decrease in heart rate can be reduced by m-anticholinergics (atropine and so on).

Storage conditions

Store in the original packaging at a temperature not exceeding 25°C, out of the reach of children. Do not freeze.

Shelf life - 2 years.