Pentasa, prolonged action granules 2 g, 60 sachets — Made in Germany — Free Delivery

Pentas prolonged action granules are indicated for ulcerative colitis and Crohn's disease.

Active ingredient: mesalazine;

1 sachet contains mesalazine 1 or 2 g;

Excipients: povidone, ethylcellulose.

Hypersensitivity to mesalazine, to any of the components of the preparation  or to salicylates, peptic ulcer of the stomach and duodenum in the acute stage, severe hepatic and / or renal failure, hemorrhagic diathesis.

Pentasa is taken with water or yogurt. Without chewing.

If a dose of Pentasa is missed, the missed dose should be taken at any time before the next dose.

If side effects occur, to weaken them, you can take the preparation at another time or apply the required dose in several doses during the day.

The preparation can be taken during or shortly after a meal if the patient has complaints from the stomach.

Not recommended during pregnancy unless absolutely necessary.

It is contraindicated for children under 6 years of age.

There is only limited clinical experience of overdose (eg, suicide attempts with large doses of mesalazine) that does not indicate the presence of renal or hepatic toxicity. There is no specific antidote, treatment should be symptomatic and supportive.

The most commonly observed adverse reactions in clinical studies were diarrhea, nausea, stomach pain, headache, vomiting and rash. Hypersensitivity reactions sometimes developed.

During the complex treatment of Pentas and azathioprine, 6-mercaptopurine or thioguanine, in some studies a greater frequency of myelosuppressive effects was found, which may indicate the presence of an interaction, but the mechanism of interaction has not been fully established. It is recommended to conduct regular monitoring of the level of leukocytes, and the dosing regimen of thiopurine should be adjusted.

Keep out of the reach of children.

Store in original packaging at temperatures not exceeding 25°C.

Shelf life - 2 years.