Quadevit 60 tablets — Made in Ukraine — Free Delivery
(Quadevit )
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Description Quadevit 60 tablets — Made in Ukraine — Free Delivery
Pharmacological properties
Vitamin A (retinol acetate) plays a key role in the synthesis of protein-enzymes and structural components of tissues, is necessary for the formation of epithelial cells, bones and the synthesis of rhodopsin, supports the division of immunocomponent cells, the normal synthesis of immunoglobulins and other factors of protection against infections.
Vitamin E (α-tocopherol acetate) is a physiological antioxidant that protects cell membranes from damage, stimulates the synthesis of heme and many proteins.
Vitamin B1 (thiamine hydrochloride) is an important coenzyme in the metabolism of carbohydrates and is involved in the functioning of the nervous system.
Vitamin B2 (riboflavin) is a component of flavin coenzymes - flavin mononucleotide and flavin adenine dinucleotide, which take part in redox reactions, and is a catalyst for cellular respiration.
Vitamin B6 (pyridoxine hydrochloride) plays an important role in the metabolism of amino acids, neurotransmitters and hemoglobin.
Vitamin B12 (cyanocobalamin) is a growth factor necessary for the normal course of hematopoiesis and erythrocyte maturation, takes part in the synthesis of amino acids, nucleic acids and myelin.
Nicotinamide is a component of the cofactor NAD (H) and NADP (H), part of the glucose tolerance factor, and takes part in the processes of tissue respiration, carbohydrate and lipid metabolism.
Folic acid is necessary for the normal formation of blood cells; together with vitamin B12 stimulates erythropoiesis, takes part in the synthesis of amino acids, nucleic acids, in the exchange of choline.
Vitamin C (ascorbic acid) takes part in redox processes, is necessary for the growth and formation of bones, skin, teeth, capillary endothelium and the normal functioning of the nervous and immune systems.
Rutin reduces capillary permeability and fragility, takes part in redox processes, inhibits the action of hyaluronidase.
Calcium D-pantothenate is a part of coenzyme A, it is necessary for the normal functioning of the tricarboxylic acid cycle, the synthesis of ATP, the production of hormones and antibodies, the synthesis of acetylcholine, the absorption of potassium, glucose, and vitamin E ions from the intestine.
Copper - an essential trace element - takes an active part in iron metabolism, hemoglobin synthesis, ripening of reticulocytes, anabolic processes.
Potassium takes part in electrolyte metabolism, conduction of nerve impulses.
Phytin is a complex organic phosphorus compound containing a mixture of calcium and magnesium salts of inositol phosphoric acids; stimulates hematopoiesis, enhances the growth and development of bone tissue, improves the function of the nervous system.
Glutamic acid takes part in metabolic processes, promotes the neutralization and release of ammonia, stimulates the transmission of excitation in the synapses of the central nervous system.
Methionine belongs to essential amino acids, is necessary for the growth and nitrogen balance of the body, takes part in the processes of remethylation and transsulfonation, and prevents fatty infiltration of liver cells.
Vitamins and trace elements are found in Quadevit in physiological, balanced doses that meet the needs of the human body.
The pharmacokinetics of the preparation have not been studied.
Indications
The preparation is indicated as a prophylactic and therapeutic agent:
with mental and physical stress;
with hypovitaminosis, increased body needs for vitamins and microelements due to unbalanced nutrition, adherence to a special diet, gastrointestinal disorders;
during the recovery period after severe illnesses, operations, injuries and stressful situations;
to increase the general resistance of the body and prevent infectious diseases during epidemics (such as, for example, influenza);
to stimulate the healing of wounds, burns;
in order to reduce toxicity and reduce the severity of side effects during antibiotic therapy, during and after chemotherapy;
in the complex treatment of atherosclerosis, cerebrovascular accidents and cardiovascular insufficiency.
Application
The preparation is taken orally after meals.
For prophylactic purposes, Kvadevit is prescribed for adults and children over the age of 14, 1 tablet per day, for the elderly - 1 tablet 2 times a day. The duration of the prophylactic course is 1–2 months.
For therapeutic purposes, 1 tablet is used 3 times a day. The course of treatment is 3-4 weeks. Repeated courses are carried out after a 3-month break.
During pregnancy and lactation, the preparation is used exclusively as directed by a doctor. In the first trimester - no more than 1 tablet per day, in the II and III trimester - no more than 2 tablets per day. During the period of breastfeeding, for a prophylactic purpose, take 1 tablet per day, with a medical one - 1 tablet 2 times a day.
Contraindications
Hypersensitivity to the components of the preparation, severe renal dysfunction, gout, hyperuricemia, nephrolithiasis, erythremia, erythrocytosis, thromboembolism, active form of pulmonary tuberculosis, fructose intolerance, thrombophlebitis, hypervitaminosis a and e, metabolic disorders of iron or copper, thyrotoxiconephritis, chronic grythritis heart failure, history of sarcoidosis, active peptic ulcer of the stomach and duodenum.
Side effects
In the recommended doses, the preparation is well tolerated and rarely causes side effects, which, as a rule, are associated with an individual intolerance to one of the components of the preparation.
From the side of the immune system: in persons with hypersensitivity, allergic reactions are possible, including anaphylactic shock, angioedema, hyperthermia; bronchospasm in persons with hypersensitivity to vitamins A, C, group B.
On the part of the skin and subcutaneous tissue: rashes, hives, itching, redness of the skin.
From the digestive tract: dyspeptic disorders, nausea, vomiting, diarrhea, epigastric pain, belching, constipation, possibly an increase in gastric acid secretion.
From the nervous system: headache, dizziness, irritability, drowsiness.
Others: the color of urine is possible yellow, hyperhidrosis, visual impairment.
With prolonged use of the preparation in high doses, irritation of the mucous membrane of the digestive tract, arrhythmias, paresthesias, hyperuricemia, a transient increase in the activity of AST, LDH, ALP, decreased glucose tolerance, hyperglycemia, impaired renal function, dryness and cracks on the palms and feet, hair loss , seborrheic rashes.
Special instructions
When using the preparation, it is necessary to observe the dose and duration of the course of administration.
In the absence of a therapeutic effect or the appearance of undesirable reactions, you should consult a doctor for advice on the further use of the preparation.
It is possible that urine stains yellow, which is a safe symptom and is explained by the presence of riboflavin in the preparation.
The preparation is prescribed with caution in severe liver damage, gastric and duodenal ulcers, patients with nephritis, chronic pancreatitis, cholelithiasis, cardiac decompensation, coronary artery disease, diabetes mellitus, patients with neoplasms (except for cases accompanied by megaloblastic anemia), urolithiasis.
When using Kvadevit, like other multivitamin preparations, a full-fledged protein diet is required, which promotes better absorption and metabolism of vitamins, especially water-soluble ones.
Kvadevit is not recommended to be prescribed together with other vitamins and preparations containing trace elements, due to the possible overdose of the latter.
Use during pregnancy and lactation. During pregnancy and lactation, the preparation is taken only on the recommendation of a doctor.
The dose of vitamin A should not exceed 5000 IU for pregnant women and women planning a pregnancy.
Retinol should not be taken in high doses (over 10,000 IU) during breastfeeding due to the risk of developing hypervitaminosis A in infants.
Children. This dosage form is not intended for use in children under the age of 14.
The ability to influence the reaction rate when driving or working with other mechanisms. There are no data on the effect of the preparation on the ability to drive a car or work with complex mechanisms.
Interactions
The preparation is not recommended to be taken simultaneously with other multivitamins, since the latter may be overdose in the body.
Vitamins A and E mutually enhance the effect and are synergistic. Retinol reduces the severity of the anti-inflammatory effect of glucocorticoids. Cannot be taken simultaneously with nitrites and cholestyramine, as they interfere with the absorption of retinol.
Vitamin A should not be given with retinoids because the combination is toxic.
Preparations containing iron inhibit the effect of vitamin E. Vitamin E should not be used together with preparations of iron, silver, agents with an alkaline medium (sodium bicarbonate, trisamine, etc.), indirect anticoagulants (dicumarin, neodycoumarin, etc.) ). Alpha-tocopherol acetate enhances the action of steroidal and non-steroidal anti-inflammatory preparations (sodium diclofenac, ibuprofen, prednisolone, etc.).
Vitamin C enhances the effect of sulfonamides (risk of crystalluria), penicillin, increases iron absorption, reduces the effectiveness of heparin and indirect anticoagulants. The absorption of vitamin C decreases with simultaneous use with oral contraceptives.
Vitamin B6 weakens the effect of levodopa, prevents or reduces the severity of toxic manifestations, which are noted when using isoniazid and other anti-tuberculosis preparations.
Thiamine, influencing the polarization processes in the neuromuscular synapses, can weaken the curariform effect.
PASK, cimetidine, calcium preparations, alcohol reduce the absorption of vitamin B12.
Folic acid reduces plasma concentrations of phenytoin; with other antiepileptic preparations, a mutual decrease in clinical efficacy is possible.
Riboflavin is incompatible with streptomycin and reduces the effectiveness of antibacterial preparations (oxytetracycline, doxycycline, erythromycin, tetracycline and lincomycin).
The tricyclic antidepressants, imipramine and amitriptyline, inhibit riboflavin metabolism, especially in the heart tissue.
Overdose
No cases of preparation overdose have been reported. in case of an overdose, allergic reactions (itching, skin flushing, skin rashes) and dyspeptic phenomena (nausea, vomiting, diarrhea, epigastric pain), changes in the skin and hair, liver dysfunction, headache, drowsiness, lethargy, facial flushing may occur , irritability.
Treatment: cancel the preparation, symptomatic therapy.
Storage conditions
In its original packaging at a temperature not exceeding 25 °
Tags: Quadevit
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