TRAVATAN EYE DROPS 2,5ML — MADE IN BELGIUM — FREE SHIPPING
Product description
Travatan eye drops - is an antiglaucoma preparation that is an aqueous solution of travoprost
(a synthetic analogue of prostaglandin F2-alpha) for use in ophthalmic
practice. It is prescribed to lower intraocular pressure in patients with
glaucoma and to treat ophthalmic hypertension. The mechanism of action of the preparation
is due to the stimulation of the outflow of the intraocular fluid filling the
space between the lens and the cornea, leading to a decrease in intraocular
pressure. The preparation prevents or slows the further progression of glaucoma
and helps to avoid the occurrence of severe complications.
Travatan eye drops - antiglaucoma
preparation. Synthetic analogue of prostaglandin F2α.
It is a highly selective agonist of prostaglandin FP
receptors. Reduces intraocular pressure due to increased uveoscleral outflow of
aqueous humor.
Intraocular pressure decreases approximately 2 hours
after application of the preparation, the maximum effect is achieved after 12
hours.
Pharmacokinetics
Absorption and Metabolism
Travoprost is absorbed through the cornea of the eye,
where hydrolysis of travoprost occurs to a biologically active form -
travoprost acid.
Cmax of travoprost in blood plasma is reached within
30 minutes after topical application and is 25 pg / ml or less.
Excretion
Travoprost is quickly removed from the plasma, within
an hour the concentration drops below the detection threshold (<10 pg / ml).
Travoprost is excreted as inactive metabolites mainly
with bile (61%), the rest is excreted by the kidneys.
Indications:
Decreased elevated intraocular pressure under the
following conditions:
- open-angle
glaucoma;
- increased
ophthalmotonus.
Contraindications:
- children
and adolescents under 18;
- hypersensitivity to the components of the preparation.
Caution should be given to patients who have risk
factors for developing macular edema (aphakia, pseudofakia, damage to the
posterior capsule of the lens), with acute iritis, uveitis.
Special instructions:
The preparation can cause a gradual change in eye
color by increasing the amount of brown pigment in the iris. This effect is
revealed mainly in patients with mixed iris color, for example, blue-brown,
gray-brown, green-brown or yellow-brown, which is explained by the increase in
melanin content in the stromal melanocytes of the iris. Typically, brown
pigmentation spreads concentrically around the pupil to the periphery of the
iris of the eyes, while the entire iris or parts of it can acquire a more
intense brown color.
In patients with uniformly colored eyes of blue, gray,
green or brown, eye color changes after two years of use of the preparation
were very rare. The color change is not accompanied by any clinical symptoms or
pathological changes.
After the preparation was discontinued, there was no
further increase in the amount of brown pigment, but the already developed
color change may be irreversible.
Before starting treatment, patients should be informed
about the possibility of changing eye color.
Treatment of only one eye can lead to permanent
heterochromia.
In the presence of nevi or lentigo on the iris, their
changes were not observed under the influence of the preparation.
The preparation may cause darkening, thickening and
lengthening of the eyelashes and / or an increase in their number; rarely -
darkening of the skin of the eyelids.
Travatan can be used in combination with other
antiglaucoma preparations for topical use. In this case, the interval between
their use should be at least 5 minutes.
When wearing contact lenses before instillation of the
preparation, the lens should be removed and reassembled no earlier than 20
minutes after the procedure.
The bottle must be closed after each use.
Side effects:
From the side of the organ of vision: in 35% of cases
- transient weakly expressed conjunctival hyperemia, passing alone; in 5-10% of
cases - reduced visual acuity, a feeling of discomfort and foreign body, pain,
itching, burning sensation in the eyes; in 1-4% of cases - visual disorders,
blepharitis, fog before the eyes, cataracts, conjunctivitis, dry conjunctiva,
changes in color of the iris, keratitis, crust formation on the edges of the
eyelids, photophobia, subconjunctival hemorrhages and increased lacrimation.
From the cardiovascular system: in 1-5% of cases - an
increase or decrease in blood pressure, bradycardia, angina pectoris, chest pain,
hypercholesterolemia.
From the side of the central nervous system: in 1-5%
of cases - general anxiety, headache, depression.
From the urinary system: in 1-5% of cases - urinary
incontinence and urinary system infection.
From the musculoskeletal system: in 1-5% of cases -
arthritis, back pain.
Other: in 1-5% of cases - flu-like syndrome,
sinusitis, bronchitis, dyspepsia.
Suggested Use:
The preparation is instilled in 1 drop in the
conjunctival sac of the affected eye (eye) 1 time / day, preferably in the
evening. More frequent use of the preparation may lead to a decrease in its
effectiveness.
Packaging:
- Comes in original packaging. Item is brand
new and unopened.
Storage:
- Keep away from direct sunlight.
- Keep locked and away from children.
- Store in dry place at room temperature.
- Do not exceed storage temperature higher
than 25 C
Important notice- the outer box design may vary before prior notice!
Tags: TRAVATAN
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