Valavir 500mg 42 tablets — Made in Ukraine — Free Delivery

Product description

Valavir tablets are indicated for:

• Treatment of herpes zoster (herpes zoster).
• Treating infections of the skin and mucous membranes caused by the herpes simplex virus, including primary and recurrent genital herpes.
• Treating herpes labialis (labial fever).
• Preventive treatment (suppression) of recurrent infections of the skin and mucous membranes caused by the herpes simplex virus, including genital herpes.
• Reducing the transmission of genital herpes virus to a healthy partner when using Valavir as a suppressive therapy in combination with safe sex.
• Prevention of cytomegalovirus infection and disease after organ transplantation.

Structure

Active ingredient: valaciclovir;

1 tablet contains valaciclovir hydrochloride 556 mg in terms of valacyclovir 100% anhydrous substance 500 mg;

Excipients: microcrystalline cellulose (101), povidone, anhydrous colloidal silicon dioxide, crospovidone, magnesium stearate;

Shell composition: Sepifilm 050 (methyl hydroxypropyl cellulose, microcrystalline cellulose, acetylated (or ester acetates) mono- and diglycerides)), kandurin.

Contraindications

Valavir is contraindicated in patients with hypersensitivity to valacyclovir, acyclovir, or any component of the drug.

Mode of application

Treatment of herpes zoster: for adults, appoint 1000 mg (2 tablets) of Valavir 3 times a day for 7 days.

Treatment of infections caused by the herpes simplex virus. Patients with normal immunity (adults): 500 mg (1 tablet) of the drug 2 times a day.

Application features

Pregnant

Can be used only when the potential benefit of the treatment to the mother outweighs the potential risk to the fetus.

Children

It is used for children over 12 years of age for the prevention of cytomegalovirus infection and disease.

Drivers

Carefully.

Overdose

Symptoms Overdose of valacyclovir has reported the development of acute renal failure and neurological symptoms, including confusion, hallucinations, agitation, decreased mental capacity and coma. Nausea and vomiting may have been observed. To prevent unintentional overdose, use caution. Many cases of overdose have been associated with the use of the drug for the treatment of patients with renal insufficiency and elderly patients, for whom the dose has not been reduced accordingly.

Treatment. Patients need to be closely monitored for toxicity. Hemodialysis significantly accelerates the elimination of acyclovir from the blood and therefore it can be considered the optimal treatment for symptomatic overdose.

Side effects

Among the more serious adverse reactions were reports of thrombotic thrombocytopenic purpura / hemolytic uremic syndrome, acute renal failure, and neurological disorders.

Interaction

No clinically significant forms of interaction were identified.

Patients who receive higher doses of Valavir (4 g or more per day) should be careful when prescribing concomitantly with drugs that compete with acyclovir for the elimination route, as this can lead to an increase in plasma levels of one or both drugs and their metabolites ... With simultaneous use with mycophenolate mofetil (an immunosuppressive drug used after organ transplant), the plasma level of acyclovir and the inactive metabolite of mycophenolate mofetil increases.

You should also be careful (with monitoring changes in renal function) while prescribing high doses of Valavir (4 g or more) and other drugs that affect renal function (for example, cyclosporine, tacrolimus).

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life is 3 years.